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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Phase 2 Interventional Results available

Use of Aromatherapy to Reduce Symptom Burden

NCT05251337
Conditions
Anxiety, Chemotherapy-induced Nausea and Vomiting
Interventions
Essential oils, Placebo
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 100 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Chemotherapy Symptoms
Interventions
Ginger, Lavender, Orange, Jojoba
Drug
Lead sponsor
University of Rochester
Other
Eligibility
21 Years to 89 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers

Aromatherapy for Anxiety Among Children With Autism Spectrum Disorder

NCT03818490
Conditions
Anxiety, Autism Spectrum Disorder
Interventions
Bergamot Aromatherapy
Other
Lead sponsor
Nutraceuticals Research Institute
Other
Eligibility
6 Years to 11 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Franklin, Tennessee
Conditions
Gastrointestinal Cancer, Neuroendocrine Carcinoma, Skin Cancer
Interventions
Aromatherapy and Essential Oils, Subject Diary
Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional

At-Home Olfactory Training

NCT03611673
Conditions
Olfactory Disorder
Interventions
Smell Test
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Kansas City, Kansas
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Effects of Lavender Oil on Postoperative Pain, Sleep Quality and Mood

NCT03093454
Conditions
Pain, Postoperative
Interventions
Lavender Essential Oil
Drug
Lead sponsor
Scott Hollenbeck, MD
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Nausea, Vomiting
Interventions
Peppermint Essential Oil, Ginger Essential Oil, or Pure Vanilla Extract
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years to 89 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Hershey, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Essential Oils and Post COVID-19 Fatigue

NCT04980573
Conditions
Covid19, Fatigue
Interventions
Aromatherapy, Placebo
Other
Lead sponsor
Nutraceuticals Research Institute
Other
Eligibility
19 Years to 49 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Franklin, Tennessee
Completed Not applicable Interventional Accepts healthy volunteers

Aromatherapy for Stress and Burnout Among Healthcare Providers

NCT05114655
Conditions
Stress, Burnout, Professional, Stress, Job
Interventions
Herbaceous Essential Oil Blend, Citrus Essential Oil Blend, Inert Oil
Other
Lead sponsor
Nutraceuticals Research Institute
Other
Eligibility
20 Years to 59 Years
Enrollment
114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Franklin, Tennessee
Not listed Not applicable Interventional Accepts healthy volunteers

The Effect of Aromatherapy on COVID-19-induced Anxiety

NCT04495842
Conditions
Stress, Covid19, Anxiety
Interventions
Essential Oil Blend, Control Blend
Other
Lead sponsor
Nutraceuticals Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Franklin, Tennessee
Not listed Not applicable Interventional Accepts healthy volunteers

Clary Sage Essential Oil & Pregnancy

NCT05000424
Conditions
Quality of Life, Pregnancy Related
Interventions
Clary Sage Massage Oil, Inert Massage Oil
Other
Lead sponsor
Nutraceuticals Research Institute
Other
Eligibility
20 Years to 39 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Franklin, Tennessee
Conditions
Chronic Nausea, Anxiety
Interventions
Inhaled Essential Oils, Wearable TENS Device
Other · Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Essential Oil Inhalation and Acute Stress Response in Healthy Adults

NCT07473544
Conditions
Psychological Stress
Interventions
Essential Oil Inhalation, Placebo Aroma Stick
Other
Lead sponsor
dōTERRA International
Industry
Eligibility
18 Years to 45 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pleasant Grove, Utah
Conditions
Nausea, Vomiting, Anxiety
Interventions
Acupuncture, Aromatherapy
Other
Lead sponsor
Englewood Hospital and Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Englewood, New Jersey
Conditions
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Interventions
Aromatherapy and Essential Oils, Questionnaire Administration
Procedure · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Duarte, California • Irvine, California
Completed Phase 1 Interventional Accepts healthy volunteers Results available

The Effects of Smell on Mood and Physical Responses

NCT00097253
Conditions
Stress, Anxiety, Depression
Interventions
Exposure to relaxant and stimulant odors
Behavioral
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 44 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Joint Diseases
Interventions
Adjunctive use of lavender and peppermint essential oils
Dietary Supplement
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Aroma on Fatigue Scores Among Women With Hypothyroidism

NCT03465176
Conditions
Fatigue, Hypothyroidism
Interventions
Aromatherapy Blend, Placebo
Other
Lead sponsor
Nutraceuticals Research Institute
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Franklin, Tennessee
Conditions
Healthy
Interventions
Placebo, Cognitive Support System
Other
Lead sponsor
dōTERRA International
Industry
Eligibility
18 Years to 64 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Pleasant Grove, Utah
Conditions
Nursing Personnel
Interventions
Oil Inhalation Patch
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Lebanon, New Hampshire
Suspended Not applicable Interventional Accepts healthy volunteers

Aromatherapy Randomization of Pain Management in Adults

NCT03377088
Conditions
Back Pain, Back Pain, Low, Sciatica
Interventions
Rose oil, Almond Oil
Other
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 110 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Stony Brook, New York
Not listed Not applicable Interventional Accepts healthy volunteers

Aromatherapy Using a Nasal Clip After Surgery

NCT02189980
Conditions
Post-operative Nausea
Interventions
Aromatherapy blend, Duration of effectiveness of the essential oil blend, Participant comfort using the nasal clip delivery system
Other
Lead sponsor
Balanced Health plus
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Charlotte, North Carolina
Conditions
Anxiety and Fear, Pain
Interventions
STILL QuickTAB Medipack blended scent aromatherapy, manufactured by Soothing Scents
Other
Lead sponsor
Stanford University
Other
Eligibility
4 Years to 18 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Stanford, California
Conditions
Aromatherapy, Anxiety, Stress, Emergency Department
Interventions
Lavender Aromatherapy, Unscented Aromatherapy
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts