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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Essure Clear all
Completed No phase listed Observational

Proportion of Hysterectomy After Female Sterilization

NCT02532361
View directory record Official record
Conditions
Hysterectomy
Interventions
Hysteroscopic device placement including Essure (ESS305, BAY1454032), Tubal ligation
Device · Procedure
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 49 Years · Female only
Enrollment
10,578 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
New Jersey, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 22, 2016 · Synced Sep 10, 2026, 2:04 AM EDT
Completed No phase listed Observational Results available

A Study to Evaluate the Effectiveness of Essure Post-NovaSure Radiofrequency Endometrial Ablation Procedure Following a Successful Essure Confirmation Test

NCT01740687
View directory record Official record
Conditions
Contraception, Menorrhagia
Interventions
ESS305 (Essure, BAY1454032), NovaSure
Device · Procedure
Lead sponsor
Bayer
Industry
Eligibility
21 Years to 50 Years · Female only
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
17
States / cities
Aurora, Colorado • Ocala, Florida • Decatur, Illinois + 14 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2023 · Synced Sep 10, 2026, 2:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Real World Effectiveness and Safety of Hysteroscopic (Essure®) Compared to Laparoscopic Sterilization

NCT03438682
View directory record Official record
Conditions
Sterility, Female, Contraception, Contraceptive Device; Complications
Interventions
Essure, Laparoscopic sterilization, Intrauterine Device (IUD)
Device · Procedure
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
89,203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Intrauterine Lidocaine Infusion for Essure Sterilization Procedures

NCT00613834
View directory record Official record
Conditions
Pain
Interventions
Lidocaine, Sterile Saline
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Sep 10, 2026, 2:04 AM EDT
Withdrawn No phase listed Observational

The Effect of Birth Control Methods on Anti-Mullerian Hormone (AMH) Levels

NCT01308931
View directory record Official record
Conditions
Birth Control
Interventions
Not listed
Lead sponsor
Valleywise Health
Other
Eligibility
25 Years to 40 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
3
States / cities
Phoenix, Arizona • Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 4, 2014 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Safety and Effectiveness of the Essure (Model ESS505) Device to Prevent Pregnancy in Women

NCT01948882
View directory record Official record
Conditions
Contraception
Interventions
ESS505 (BAY1454033)
Device
Lead sponsor
Bayer
Industry
Eligibility
21 Years to 44 Years · Female only
Enrollment
660 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2024
U.S. locations
17
States / cities
Aurora, Colorado • Denver, Colorado • Wellington, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Sep 10, 2026, 2:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Development of an Intrauterine Pressure Threshold to Confirm Tubal Occlusion

NCT04071392
View directory record Official record
Conditions
Sterilization, Female, Fallopian Tube Occlusion
Interventions
Hysterosalpingogram (HSG)
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 9, 2019 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study to Assess Outcomes in Women Undergoing Either Hysteroscopic Sterilization (Essure®) or Laparoscopic Tubal Sterilization

NCT03127722
View directory record Official record
Conditions
Contraception
Interventions
Blood draw, ESSURE (BAY1454032), Laparoscopic tubal sterilization
Procedure · Device
Lead sponsor
Bayer
Industry
Eligibility
21 Years and older · Female only
Enrollment
990 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
57
States / cities
Chandler, Arizona • Phoenix, Arizona • Tucson, Arizona + 47 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 10, 2026, 2:04 AM EDT
Not listed No phase listed Observational

Post Approval NovaSure Essure Labeling Study

NCT01934244
View directory record Official record
Conditions
Menorrhagia
Interventions
NovaSure Endometrial Ablation
Device
Lead sponsor
Hologic, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
318 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
14
States / cities
Chandler, Arizona • Arvada, Colorado • Sarasota, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2018 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Essure Transvaginal Ultrasound (TVU) Study

NCT01327105
View directory record Official record
Conditions
Contraceptive Usage
Interventions
TVU
Device
Lead sponsor
Bayer
Industry
Eligibility
21 Years to 44 Years · Female only
Enrollment
547 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2023
U.S. locations
13
States / cities
Chandler, Arizona • Glendale, Arizona • Phoenix, Arizona + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nitrous Oxide for Pain Management During In-office Transcervical Sterilization

NCT02312739
View directory record Official record
Conditions
Contraception, Inhalation of Nitrous Oxide
Interventions
In-office Transcervical Sterilization (Essure®), Standard Oral pain medications, Intramuscular Ketorolac, Placebo pills, Oxygen, Nitrous Oxide
Procedure · Drug · Other
Lead sponsor
University of New Mexico
Other
Eligibility
21 Years and older · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jul 5, 2016 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Essure (Model ESS310) Placement Rate Study

NCT02064413
View directory record Official record
Conditions
Contraception
Interventions
ESS310 (BAY1454032)
Device
Lead sponsor
Bayer
Industry
Eligibility
21 Years to 44 Years · Female only
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
16
States / cities
Glendale, Arizona • Phoenix, Arizona • Colorado Springs, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Sep 10, 2026, 2:04 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Use of Essure® Micro-inserts in Women With Hydrosalpinx Prior to In Vitro Fertilization: A Prospective, Multicenter, International Feasibility Study

NCT01221974
View directory record Official record
Conditions
Women Who Suffer From Hydrosalpinx That is Causing Infertility and Whom Want a Safer Way of Treamtent
Interventions
Essure Micro Insert
Device
Lead sponsor
Reproductive Science Center
Industry
Eligibility
21 Years to 38 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2008
U.S. locations
1
States / cities
San Ramon, California
Source: ClinicalTrials.gov public record
Updated Oct 17, 2010 · Synced Sep 10, 2026, 2:04 AM EDT
Completed No phase listed Observational

Characterization of the Essure System Tubal Sterilization Using Ultrasound and X-Ray

NCT00588497
View directory record Official record
Conditions
Tubal Sterilization
Interventions
Micro-insert hysteroscopic sterilization, Plain abdominal Xray, Pelvic Ultrasound, Hysterosalpingogram
Procedure · Radiation
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 22, 2011 · Synced Sep 10, 2026, 2:04 AM EDT
Terminated Not applicable Interventional Results available

Can SIS Using Air Bubbles Replace HSG for Fallopian Tubal Patency After Essure Placement

NCT02628873
View directory record Official record
Conditions
Contraception
Interventions
HyCoSy
Device
Lead sponsor
Wright State University
Other
Eligibility
18 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced Sep 10, 2026, 2:04 AM EDT