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Showing 1–24 of 52 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Not applicable Interventional Results available

Clinical Investigation of the WaveLight® EX500 Excimer Laser

NCT04805593
Conditions
Hyperopia, Hyperopic Astigmatism
Interventions
WaveLight EX500 excimer laser system, LASIK
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
5
States / cities
Overland Park, Kansas • Kansas City, Missouri • Greensboro, North Carolina + 2 more
Not listed Phase 4 Interventional Accepts healthy volunteers

Multi Laser Platform Comparison Study for LASIK

NCT00770094
Conditions
Myopia, Astigmatism
Interventions
Excimer Lasers, Excimer Laser for the LASIK procedure, Excimer Laser for LASIK
Device
Lead sponsor
Durrie Vision
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
3
States / cities
Atlanta, Georgia • Edina, Minnesota • McLean, Virginia
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Effectiveness of Wavefront-Guided LASIK Correction of Hyperopic Refractive Errors

NCT01675479
Conditions
Hyperopia
Interventions
LASIK correction of hyperopic refractive errors
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
9
States / cities
Los Angeles, California • Miami, Florida • Chicago, Illinois + 6 more
Conditions
Peripheral Vascular Disease
Interventions
Cryoplasty (PolarCath peripheral balloon catheter), Laser Angioplasty (Spectranetics), SilverHawk Atherectomy, Viabahn Endograft, Angioplasty/Stent (Guidant "Absolute" stent)
Procedure · Device
Lead sponsor
Arizona Heart Institute
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Phoenix, Arizona
Conditions
Hyperopia
Interventions
MEL 80 Hyperopic LASIK Treatment
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
21 Years and older
Enrollment
189 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
6
States / cities
San Diego, California • Greenwood Village, Colorado • Kansas City, Missouri + 3 more
Conditions
Myopia
Interventions
LASIK, PRK, Small target contrast sensitivity and disability glare
Procedure · Behavioral
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Peripheral Arterial Disease
Interventions
RA-308 Excimer Laser and DABRA Catheter
Device
Lead sponsor
Ra Medical Systems
Industry
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
El Centro, California • San Diego, California • Hattiesburg, Mississippi
Conditions
Peripheral Arterial Disease
Interventions
Atherectomy
Device
Lead sponsor
Ra Medical Systems
Industry
Eligibility
22 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
10
States / cities
El Centro, California • Merced, California • Gainesville, Florida + 7 more
Completed Not applicable Interventional Accepts healthy volunteers

Goblet Cell Response and Dry Eye Symptoms After PRK and LASIK

NCT00411827
Conditions
Keratoconjunctivitis Sicca
Interventions
PRK with conjunctival impression cytology before and after surgery, LASIK with conjunctival impression cytology before and after surgery
Procedure
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
21 Years to 40 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Myopia, Myopic Astigmatism
Interventions
Technolas® TENEO 317 Model 2
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
22 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
10
States / cities
Newport Beach, California • Blaine, Minnesota • Bloomington, Minnesota + 7 more
Conditions
Lung Cancer
Interventions
PHOTODYNAMIC THERAPY (PDT)
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years to 75 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 2006
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Myopia, Astigmatism
Interventions
Topography Guided LASIK Surgery, Small Incision Lenticule Extraction Surgery
Device
Lead sponsor
Hoopes Vision
Other
Eligibility
22 Years to 50 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Draper, Utah
Terminated Not applicable Interventional Results available

Excimer Laser Phototherapy Outcomes in the Treatment of Psoriasis

NCT02294981
Conditions
Psoriasis
Interventions
Excimer laser phototherapy
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
San Francisco, California
Conditions
Vision Correction
Interventions
Advanced CustomVue™ iLASIK procedure, WaveScan WaveFront® System, STAR S4 IR™ Excimer Laser System and IntraLase™ FS System
Procedure · Device
Lead sponsor
Innovative Medical
Industry
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Miami, Florida
Conditions
Myopia, Astigmatism
Interventions
Photorefractive keratectomy, Laser in-situ keratomileusis
Procedure
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Stanford, California
Recruiting Not applicable Interventional

Laser In Situ Fenestration Study

NCT06411990
Conditions
Aortic Aneurysm, Endovascular Aneurysm Repair
Interventions
Fenestrated Endovascular Aneurysm Repair using the LIFE Device System
Device
Lead sponsor
Jonathan Bath
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
1
States / cities
Columbia, Missouri
Completed Not applicable Interventional Accepts healthy volunteers

Wavefront-guided PRK vs Wavefront-optimized PRK

NCT02091934
Conditions
Myopia, Astigmatism
Interventions
Wavefront-guided PRK, Wavefront-optimized PRK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 60 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Glaucoma, Primary Open Angle
Interventions
ELIOS Procedure
Device
Lead sponsor
Elios Vision, Inc.
Industry
Eligibility
45 Years and older
Enrollment
318 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
20
States / cities
Glendale, Arizona • Petaluma, California • Fort Collins, Colorado + 16 more
Conditions
Chronic Stable Plaque Psoriasis
Interventions
Clobex Spray, Vectical Ointment, Excimer Laser
Drug · Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
San Francisco, California
Conditions
Myopia, Astigmatism
Interventions
Ray-Tracing Guided LASIK, Keratorefractive Lenticule Extraction (KLEx), WaveFront Optimized LASIK, Topography Guided LASIK
Device
Lead sponsor
Hoopes Vision
Other
Eligibility
22 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Draper, Utah
Completed No phase listed Observational Accepts healthy volunteers

Wavefront-guided Versus Wavefront-optimized LASIK for Nearsightedness

NCT01138189
Conditions
Myopia, Astigmatism
Interventions
Wavefront-guided LASIK, Wavefront-optimized LASIK
Procedure
Lead sponsor
Edward E. Manche
Other
Eligibility
21 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Stanford, California
Withdrawn Not applicable Interventional Accepts healthy volunteers

Childhood Alopecia Areata Study Using the 308-nm Excimer Laser

NCT01736007
Conditions
Alopecia Areata
Interventions
308-nm excimer laser to alopecia patch, Liquid light guide tip on laser
Device
Lead sponsor
Phoenix Children's Hospital
Other
Eligibility
6 Years to 17 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Phoenix, Arizona
Conditions
Myopia, Astigmatism
Interventions
WaveLight EX500 Excimer Laser System, VisuMax Surgical Laser
Device
Lead sponsor
59th Medical Wing
Federal
Eligibility
21 Years to 50 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
IVC Filters
Interventions
Prospective Chart Review
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 100 Years
Enrollment
535 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2022
U.S. locations
1
States / cities
Chicago, Illinois