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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Exercise - High-intensity exercise Clear all
Recruiting Phase 2Phase 3 Interventional

Exercise and Intranasal Insulin in Type 2 Diabetes

NCT07675499
View directory record Official record
Conditions
Type 2 Diabetes, Insulin Sensitivity/Resistance, Cognition, Brain Blood Flow
Interventions
Intranasal Insulin, Intranasal Placebo, High Intensity Exercise
Drug · Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
55 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
4
States / cities
New Brunswick, New Jersey • Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 13, 2026, 8:02 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Nutritional and Contractile Regulation of Muscle Growth

NCT00891696
View directory record Official record
Conditions
Sarcopenia
Interventions
Rapamycin, Amino acid supplementation, Low-intensity resistance exercise, Sodium nitroprusside, Blood flow restriction cuff
Drug · Other · Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 85 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated May 3, 2017 · Synced Sep 13, 2026, 8:02 AM EDT
Recruiting Not applicable Interventional

HIIT Effects on Cardiometabolic Health

NCT05838950
View directory record Official record
Conditions
Obesity, Cardiovascular Diseases, Metabolic Disease, High-intensity Interval Training
Interventions
high-intensity interval training intervention
Other
Lead sponsor
Syracuse University
Other
Eligibility
18 Years to 25 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Sep 13, 2026, 8:02 AM EDT
Completed Not applicable Interventional Results available

Pragmatic Cyclical Lower Extremity Exercise Trial for Parkinson's Disease

NCT04000360
View directory record Official record
Conditions
Parkinson Disease
Interventions
High-Intensity Aerobic Exercise (AE), Usual and Customary Care (UCC)
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Cleveland, Ohio • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 17, 2025 · Synced Sep 13, 2026, 8:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dose Effect of a Plant Extract on Fatigue

NCT03870126
View directory record Official record
Conditions
Mental Energy, Physical Performance
Interventions
Flavored beverage
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 49 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Sep 13, 2026, 8:02 AM EDT
Active, not recruiting Phase 1 Interventional

A Study of Exercise and Pharmacologic Intervention on Systemic Inflammation

NCT07058974
View directory record Official record
Conditions
Smokers, Former Smokers
Interventions
lamivudine, rapamycin, Exercise Regimen, Spermidine
Drug · Behavioral · Dietary Supplement
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
60 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Sep 13, 2026, 8:02 AM EDT
Completed Not applicable Interventional Results available

Metabolic Adaptations in Response to High Intensity Interval Training in Obese Adults

NCT02706093
View directory record Official record
Conditions
Glucose Intolerance
Interventions
High Intensity Interval Training (HIIT), Moderate-intensity continuous training (MICT)
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 40 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 13, 2026, 8:02 AM EDT
Not listed Not applicable Interventional

Women in Cardiac Rehabilitation: Optimizing the Training Response

NCT03438968
View directory record Official record
Conditions
Exercise Training, Coronary Artery Disease, Women, Cardiac Rehabilitation
Interventions
Exercise training
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Feb 19, 2018 · Synced Sep 13, 2026, 8:02 AM EDT
Completed Not applicable Interventional

Mild Cognitive Impairment, Buddy Supported Exercise/ My Buddy Study

NCT01561820
View directory record Official record
Conditions
Mild Cognitive Impairment, Cognitive Disorders
Interventions
5-month aerobic exercise intervention
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
60 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Sep 13, 2026, 8:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nighttime Macronutrient Choice and Combined Resistance and High-intensity Interval Training

NCT01830946
View directory record Official record
Conditions
Obesity
Interventions
Whey Protein, Combined Resistance and High-Intensity Interval training, Casein Protein
Other
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 45 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Apr 14, 2013 · Synced Sep 13, 2026, 8:02 AM EDT
Recruiting Not applicable Interventional

Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle

NCT05551325
View directory record Official record
Conditions
Critical Illness, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Unspecified
Interventions
Chronobundle - light, chronobundle - feeding, chronobundle - mobility, chronobundle - sleep
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 13, 2026, 8:02 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

An Exercise RCT Targeting African-American Women With Metabolic Syndrome and High Risk for Breast Cancer

NCT02103140
View directory record Official record
Conditions
Metabolic Syndrome, Obesity
Interventions
Facility-based Exercise, Home-based Exercise
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
213 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 19, 2024 · Synced Sep 13, 2026, 8:02 AM EDT
Completed Not applicable Interventional Results available

Engaging Medically Complex Veterans in Tele-Rehabilitation Using a Biobehavioral Approach

NCT04942613
View directory record Official record
Conditions
Multimorbidity, Physical Deconditioning
Interventions
Motivational Interviewing Techniques, Physical Therapy Interventions, Education, Qualitative Interview
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Sep 13, 2026, 8:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mechanisms of Exercise-Induced Hypoalgesia

NCT06050889
View directory record Official record
Conditions
Healthy
Interventions
Positive Expectations Instructional Set, Negative Expectations Instructional Set
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 21, 2024 · Synced Sep 13, 2026, 8:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CrossFit Exercise to Improve Glucose Control for Overweight and Obese Adults

NCT02185872
View directory record Official record
Conditions
Hyperglycemia
Interventions
High-Intensity Functional Training, Aerobic and Resistance Training
Other
Lead sponsor
Kansas State University
Other
Eligibility
18 Years to 40 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Manhattan, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2015 · Synced Sep 13, 2026, 8:02 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effects of a Short-term Aerobic Interval Exercise Program on Cardiac Fat and Function in Women With Obesity: A Pilot Study

NCT04802005
View directory record Official record
Conditions
Obesity
Interventions
Aerobic Interval Training
Other
Lead sponsor
Southern Illinois University Edwardsville
Other
Eligibility
18 Years to 40 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Edwardsville, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 20, 2021 · Synced Sep 13, 2026, 8:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sex Differences in Vascular Responses to Exercise

NCT04128215
View directory record Official record
Conditions
Aging
Interventions
Control Period, Exercise Period
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
60 Years to 79 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 13, 2024 · Synced Sep 13, 2026, 8:02 AM EDT
Completed Not applicable Interventional

High Intensity Interval Training in Osteoarthritis, Effects on Metabolomics

NCT03039452
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
High intensity interval training
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
40 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 30, 2017 · Synced Sep 13, 2026, 8:02 AM EDT
Completed Not applicable Interventional

Strength Training and Medication Effects in Parkinson Disease Effects on Hypokinesia in Parkinson Disease

NCT00665184
View directory record Official record
Conditions
Parkinson Disease
Interventions
Resistance Exercise via Negative Eccentric Work, Standard care exercise training
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
40 Years to 90 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 20, 2011 · Synced Sep 13, 2026, 8:02 AM EDT
Active, not recruiting Phase 2Phase 3 Interventional Results available

Physical Activity and Dexamethasone in Reducing Cancer-Related Fatigue in Patients With Advanced Cancer

NCT02491632
View directory record Official record
Conditions
Advanced Malignant Neoplasm, Fatigue, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm, Refractory Malignant Neoplasm
Interventions
Dexamethasone, Exercise Intervention, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Questionnaire Administration
Drug · Behavioral · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 13, 2026, 8:02 AM EDT
Enrolling by invitation Not applicable Interventional

Impact of Exercise Groups on Patient Mental Health and Wellbeing in an Acute Psychiatric Inpatient Unit

NCT05859204
View directory record Official record
Conditions
Psychiatric Hospitalization, Physical Inactivity, Depression, Anxiety, Sleep
Interventions
OT-led Exercise Group, Treatment as Usual - OT Groups
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 13, 2026, 8:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Age on Glucose and Lipid Metabolism

NCT01737164
View directory record Official record
Conditions
Glucose Metabolism Disorders, Lipid Metabolism Disorders, Metabolic Diseases
Interventions
Aerobic Exercise
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 100 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 18, 2016 · Synced Sep 13, 2026, 8:02 AM EDT
Enrolling by invitation Not applicable Interventional

RIC (Remote Ischemic Conditioning) in Older Individuals

NCT06476288
View directory record Official record
Conditions
Old Age, Mobility Limitation, Debility
Interventions
Low-intensity resistance exercise training, High-Dose Remote ischemic conditioning (RIC), Low-Dose Remote ischemic conditioning (RIC)
Other
Lead sponsor
Duke University
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 13, 2026, 8:02 AM EDT
Recruiting Not applicable Interventional

Transvaginal Electrical Stimulation for Myofascial Pelvic Pain

NCT05354869
View directory record Official record
Conditions
Myofascial Pelvic Pain
Interventions
Urostym, Standard care
Device · Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 13, 2026, 8:02 AM EDT