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ClinicalTrials.gov public records Last synced Oct 14, 2026, 7:46 AM EDT

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Showing 265–288 of 543 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Exercise and Dietary Weight Loss Clear all
Completed Not applicable Interventional

PACIFIC-FIT: Providing Adults Collaborative Interventions for Ideal Changes Focused Intervention and Tracking

NCT03914508
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Memory + Behavioral Weight Loss
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Oct 14, 2026, 7:46 AM EDT
Terminated Phase 3 Interventional

A 14-Month Study On The Effects Of CP-945,598 For The Prevention Of Weight Regain In Obese Patients

NCT00483171
View directory record Official record
Conditions
Obesity
Interventions
CP-945,598, Non-pharmacological weight loss program (NPP), Low Calorie Diet
Drug · Behavioral
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 70 Years
Enrollment
699 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
9
States / cities
La Jolla, California • Denver, Colorado • Baton Rouge, Louisiana + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2012 · Synced Oct 14, 2026, 7:46 AM EDT
Terminated Not applicable Interventional Results available

Diet and Exercise Program to Promote Weight Loss and Improve Health in Men With Low- or Low-Intermediate-Risk Prostate Cancer

NCT02454517
View directory record Official record
Conditions
Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC V7, Stage IIA Prostate Cancer AJCC v7
Interventions
Behavioral Dietary Intervention, Exercise Intervention, Informational Intervention, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Questionnaire Administration
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
40 Years and older · Male only
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 4, 2023 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Age, Lifestyle, Muscle Mechanisms in Insulin Resistance

NCT00971594
View directory record Official record
Conditions
Obesity, Glucose Intolerance, Exercise Capacity
Interventions
Dietary counseling, AEX
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
50 Years and older · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 3, 2009 · Synced Oct 14, 2026, 7:46 AM EDT
Recruiting Not applicable Interventional

Endoscopic Sleeve Gastroplasty (ESG) for the Treatment of Obesity

NCT06339320
View directory record Official record
Conditions
Endoscopic Sleeve Gastroplasty, Obesity
Interventions
Endoscopic Sleeve Gastroplasty (ESG), Apollo OverStitch endoscopic suturing device
Procedure · Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2033
U.S. locations
2
States / cities
Houston, Texas • Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Apr 1, 2024 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Lifestyle Intervention and Metformin for Women With Polycystic Ovary Syndrome (PCOS)

NCT00151411
View directory record Official record
Conditions
Polycystic Ovary Syndrome
Interventions
Metformin, Placebo, Lifestyle Intervention
Drug · Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
12 Years to 39 Years · Female only
Enrollment
114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 21, 2018 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional

Peer-enhanced Intervention to Support Teen Weight Loss

NCT00285558
View directory record Official record
Conditions
Obesity
Interventions
CBT with peer-enhanced activities, CBT with supervised aerobic exercise
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
13 Years to 16 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Get Active and Eat Right: Moms at Work

NCT01668316
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Weight loss
Behavioral
Lead sponsor
University of North Carolina, Greensboro
Other
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated May 3, 2019 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional Results available

Remote Delivery of Weight Management for Adults With IDD

NCT03291509
View directory record Official record
Conditions
Obesity
Interventions
Video Conference Meetings, In-person Meetings, Enhanced Stop Light Diet, Physical Activity
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Oct 14, 2026, 7:46 AM EDT
Recruiting Not applicable Interventional

Lifestyle Change Implementation Research Network at PRC at UMass Chan

NCT07481305
View directory record Official record
Conditions
GLP - 1
Interventions
Digital Lifestyle Coaching Program
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional

Mood and Nutrition Interventions in Polycystic Ovary Syndrome

NCT01899001
View directory record Official record
Conditions
Polycystic Ovary Syndrome (PCOS)
Interventions
Cognitive Behavioral Therapy, Nutrition Counseling
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 23, 2016 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional

EMPOWER Men to Reduce Weight and Inhibit Prostate Cancer Progression

NCT04266431
View directory record Official record
Conditions
Prostatic Neoplasm
Interventions
EMPOWER
Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigating Fitness Interventions in the Elderly (INFINITE)

NCT01048736
View directory record Official record
Conditions
Obesity, Older Adults, Sedentary
Interventions
Exercise Only, Exercise + Diet
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 80 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 14, 2026, 7:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Operations Enduring Freedom and Iraqi Freedom (OEF/OIF)Veteran Preferences for Automated Physical Activity Interventions

NCT01358643
View directory record Official record
Conditions
Physical Activity
Interventions
Three home-based diet and exercise programs
Other
Lead sponsor
VA Ann Arbor Healthcare System
Federal
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 2, 2011 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Diet and/or Exercise-induced Weight Loss on Cardiovascular Risk Factors

NCT00588978
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
diet and/or exercise
Behavioral
Lead sponsor
Yale University
Other
Eligibility
40 Years to 65 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 17, 2020 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inhibitory Control and Pediatric Weight Management

NCT04747548
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Kurbo Only, Kurbo + PolyRules!
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
7 Years to 13 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2022 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional

Lifestyle Intervention to Improve Bone Quality

NCT03329963
View directory record Official record
Conditions
Aging, Obesity
Interventions
Healthy Lifestyle Intervention, Lifestyle Intervention
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
65 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional Results available

The Effects of Obesity and Obstructive Sleep Apnea on Inflammation and Heart Disease

NCT00371293
View directory record Official record
Conditions
Sleep Apnea Syndromes, Inflammation
Interventions
Weight Loss Program, CPAP therapy
Behavioral · Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2017 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SMART Weight Loss Management

NCT02997943
View directory record Official record
Conditions
Weight Loss
Interventions
Step 1 Treatment: APP, Step 1 Treatment: APP + Coaching, Step 2 Treatment Strategy: Modest Step-up, Step 2 Treatment Strategy: Vigorous Step-up
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 18, 2021 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Online Family Dyadic Skills Training for Black Adults in Behavioral Weight Loss Program

NCT05981508
View directory record Official record
Conditions
Body Weight, Body Weight Changes, Obesity, Overweight and Obesity, Overweight, Behavior, Eating, Physical Inactivity, Chronic Disease, Weight Loss, Weight Reduction
Interventions
Together, Eating and Activity, Matter Plus (TEAM+) Online, Together, Eating and Activity, Matter Plus (TEAM+) In-Person
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional

Exercise Versus Diet in the Treatment of Nonalcoholic Fatty Liver Disease

NCT01327443
View directory record Official record
Conditions
Non Alcoholic Fatty Liver Disease
Interventions
Weight loss, Exercise
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 60 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 5, 2016 · Synced Oct 14, 2026, 7:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of a Personalized vs. Standard Approach to Weight Loss Recommendations

NCT04639076
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Behavioral Weight Loss Program, Personalized Behavioral Weight Loss Program
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
20 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Oct 14, 2026, 7:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Adaptive Responses to Overfeeding and Weight

NCT03857048
View directory record Official record
Conditions
Obesity
Interventions
Weight Loss, Exercise training, Overfeeding
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 50 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 7, 2023 · Synced Oct 14, 2026, 7:46 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Examining Valence-based Effects in Self-Monitoring Feedback Messages

NCT07292389
View directory record Official record
Conditions
Obesity & Overweight, Obesity (Disorder)
Interventions
Positive Reinforcement, Positive Reinforcement + Areas for Change
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 14, 2026, 7:46 AM EDT