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ClinicalTrials.gov public records Last synced Oct 14, 2026, 1:33 PM EDT

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Showing 289–312 of 543 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Exercise and Dietary Weight Loss Clear all
Completed Phase 3 Interventional

8-week Pilot Study of Relaxation for Weight Loss in Adults With Chronic Kidney Disease

NCT00944138
View directory record Official record
Conditions
Obesity
Interventions
Relaxation methods
Behavioral
Lead sponsor
Edward Hines Jr. VA Hospital
Federal
Eligibility
18 Years to 88 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 28, 2010 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Self-compassion and Nutrition (SCAN) Study

NCT04289636
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Behavioral weight loss program, Self-compassion, Nutrition and cooking education
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Not applicable Interventional

Lifestyle Intervention Trial in Obese Elderly

NCT01065636
View directory record Official record
Conditions
Obesity
Interventions
Diet + Resistance Training, Diet + Aerobic Training, Diet + Resistance/Aerobic Exercise
Behavioral
Lead sponsor
Biomedical Research Institute of New Mexico
Other
Eligibility
65 Years to 85 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
2
States / cities
Albuquerque, New Mexico • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigating Fitness Interventions in the Elderly (INFINITE)

NCT01048736
View directory record Official record
Conditions
Obesity, Older Adults, Sedentary
Interventions
Exercise Only, Exercise + Diet
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 80 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 14, 2026, 1:33 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Weight and Shape Concern Among Women with High Body Weight

NCT05845866
View directory record Official record
Conditions
Body Image Disturbance, Overweight and Obesity, Weight Loss
Interventions
Modified Body Project, Facts about obesity, myths about weight loss, Lifestyle intervention for weight loss
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
25 Years to 70 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 14, 2026, 1:33 PM EDT
Active, not recruiting Phase 4 Interventional

Long-term Effectiveness of the Antiobesity Medication Phentermine

NCT05176626
View directory record Official record
Conditions
Obesity, Obesity; Drug, Lifestyle, Healthy
Interventions
Online Lifestyle Behavioral Therapy, Phentermine Hydrochloride 8 MG
Behavioral · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 70 Years
Enrollment
870 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Los Angeles, California • Saint Louis Park, Minnesota • Winston-Salem, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intermittent Fasting Versus Daily Caloric Restriction for Weight Loss

NCT03411356
View directory record Official record
Conditions
Obesity
Interventions
Daily Caloric Restriction (DCR), Intermittent Fasting (IMF)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 60 Years
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

ENGAGED: E-Networks Guiding Adherence to Goals for Exercise and Diet

NCT01051713
View directory record Official record
Conditions
Obesity
Interventions
Technology Supported, Standard
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 11, 2016 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Phase 2 Interventional

The Comparison of a Technology-Based System and an In-Person Behavioral Weight Loss Intervention

NCT01134874
View directory record Official record
Conditions
Obesity
Interventions
Standard weight loss intervention, Standard weight loss intervention plus technology, Technology only
Behavioral
Lead sponsor
John M. Jakicic, PhD
Other
Eligibility
18 Years to 55 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 5, 2015 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

HELP Prevent Cancer Pilot Study

NCT02960542
View directory record Official record
Conditions
Obesity, Cancer
Interventions
HELP Prevent Cancer Intervention
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Danville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 19, 2020 · Synced Oct 14, 2026, 1:33 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimal Digital Weight Loss Treatment for Rural Individuals

NCT06105957
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Core, Facilitated Weekly Group Sessions, Counselor Crafted Feedback, Individual Coaching Calls, Pre-Scripted Feedback
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
616 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Not applicable Interventional

PACE-PC: Primary Care Management of Adolescent Obesity

NCT00415974
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss
Interventions
Physician Counseling, Health Educator, Phone Counseling, Health promotion materials on physical activity and nutrition
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
11 Years to 13 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2012 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Phase 2 Interventional Results available

Survivorship Promotion In Reducing IGF-1 Trial

NCT02431676
View directory record Official record
Conditions
Breast Cancer, Prostate Cancer, Lung Cancer, Colon Cancer, Melanoma of Skin, Endometrial Cancer, Liver Cancer, Pancreatic Cancer, Rectal Cancer, Kidney Cancer, Other Solid Malignant Tumors
Interventions
Metformin, Coach Directed Behavioral Weight Loss, Self-control weight loss
Drug · Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced Oct 14, 2026, 1:33 PM EDT
Active, not recruiting Phase 2 Interventional

An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer

NCT04742751
View directory record Official record
Conditions
PreDiabetes, Adult Children
Interventions
Metformin, Digital Intervention
Drug · Behavioral
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years to 44 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Not applicable Interventional Results available

Feasibility of a Campaign Intervention Compared to a Standard Behavioral Weight Loss Intervention in Overweight and Obese Adults

NCT01803737
View directory record Official record
Conditions
Weight Loss
Interventions
Standard Behavioral Weight Loss Intervention (SBWL), Campaign Intervention (CI)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 17, 2014 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Not applicable Interventional

Valued EpiGenetic Glycemic ImprovEments Through Weight Loss

NCT02869659
View directory record Official record
Conditions
Obesity, Pre-diabetes
Interventions
Weight Loss Group, Delayed Weight Loss
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
40 Years to 65 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 31, 2020 · Synced Oct 14, 2026, 1:33 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Piloting a Generative Artificial Intelligence Chatbot in a Mobile Weight Loss Program

NCT07534254
View directory record Official record
Conditions
Overweight and/or Obesity
Interventions
AGILE Intervention, Chatbot
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 39 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Age, Lifestyle, Muscle Mechanisms in Insulin Resistance

NCT00971594
View directory record Official record
Conditions
Obesity, Glucose Intolerance, Exercise Capacity
Interventions
Dietary counseling, AEX
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
50 Years and older · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 3, 2009 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

WOOP VA: Promoting Weight Management in Primary Care

NCT05014984
View directory record Official record
Conditions
Obesity
Interventions
mental contrasting with implementation intentions, telephone-delivered, telehealth-delivered, and or in-person MOVE! or TeleMOVE!, Information About Diet, Physical Activity, and Weight Management (Baseline Visit - 10 minutes): All, Telephone MCII Check-ins (30 minutes at 3 days, 4 weeks, and 2 months after baseline visit)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
405 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Giving a Low Carbohydrate Diet to Overcome Hypertension

NCT04230928
View directory record Official record
Conditions
Hypertension, African Americans, Diet, Carbohydrate-Restricted, Risk Reduction Behavior
Interventions
Very low carbohydrate diet, Standard DPP-GLB diet, Standard DPP-GLB program modules
Other · Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 74 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of Increased Physical Activity During the Postpartum Period on Weight Loss, Body Composition, and Energy Expenditure

NCT06636305
View directory record Official record
Conditions
Weight Loss, Postpartum, Physical Activity
Interventions
physical activity intervention
Behavioral
Lead sponsor
Nicolas D. Knuth
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Towson, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 10, 2024 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Calorie Restricted, Very Low Fat Plant-based Diet and Multi-component Exercise Program on Metabolic Health

NCT02706288
View directory record Official record
Conditions
Obesity, Insulin Resistance
Interventions
Weight loss with very low fat plant-based diet and regular exercise
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 8, 2022 · Synced Oct 14, 2026, 1:33 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Muscle Insulin Resistance in Aging (Mirage)

NCT02230839
View directory record Official record
Conditions
Insulin Resistance, Sarcopenia
Interventions
Exercise, Energy Restriction-Induced Weight Loss
Behavioral
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
65 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 14, 2026, 1:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Eat Well for Life: A Weight Loss Maintenance Study

NCT01849627
View directory record Official record
Conditions
Obesity
Interventions
Low-ED, Energy Balance
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
18 Years to 70 Years
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 14, 2026, 1:33 PM EDT