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ClinicalTrials.gov public records Last synced Oct 14, 2026, 10:42 PM EDT

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Showing 433–456 of 543 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Exercise and Dietary Weight Loss Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Choosing Healthy Activities and Lifestyle Management Through Portal Support

NCT05410353
View directory record Official record
Conditions
Weight Loss, Overweight and Obesity, Behavior, Health
Interventions
Active Intervention Group, Comparison Group
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
16 Years and older
Enrollment
229 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Oct 14, 2026, 10:42 PM EDT
Recruiting Not applicable Interventional

Microrandomized Trial to Optimize Use of Burden-reducing Self-monitoring Approaches in Behavioral Obesity Treatment

NCT07228130
View directory record Official record
Conditions
Obesity & Overweight
Interventions
Online Behavioral Obesity Treatment, Full Dietary Self-monitoring, Reduced-frequency Dietary Self-monitoring, Self-Monitoring of Dietary Lapses Only, Smartwatch-based Self-monitoring of Energy Intake, Self-monitoring of Body Weight Only
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 14, 2026, 10:42 PM EDT
Active, not recruiting Not applicable Interventional

Miro-randomized Trial for Optimizing a JITAI to Reduce Dietary Lapses in Obesity Treatment

NCT04784585
View directory record Official record
Conditions
Obesity
Interventions
JITAI Enhanced Education Intervention Option, JITAI Self-Efficacy Intervention Option, JITAI Motivation Intervention Option, JITAI Self-Regulation Intervention Option, JITAI Generic Risk Alert Intervention Option (Active Comparator), Online Behavioral Obesity Treatment, JITAI No Treatment Intervention Option
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Program to Reduce Incontinence by Diet and Exercise

NCT00091988
View directory record Official record
Conditions
Urinary Incontinence
Interventions
Lifestyle & Behavioral Change Program, Structured Education Program
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
30 Years and older · Female only
Enrollment
338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
4
States / cities
Birmingham, Alabama • Little Rock, Arkansas • San Francisco, California + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Oct 14, 2026, 10:42 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Elements Vital to Treat Obesity Study

NCT04708769
View directory record Official record
Conditions
Obesity
Interventions
Smartphone App Participants (APP), Diabetes Prevention Program Participants (DPP)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 70 Years
Enrollment
524 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 14, 2026, 10:42 PM EDT
Recruiting Not applicable Interventional

Cultural Modification of an Evidence Based Healthy Lifestyle Intervention for People Post Stroke Who Identify as Hispanic/Latino

NCT06517459
View directory record Official record
Conditions
Stroke
Interventions
Group Lifestyle Balance
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced Oct 14, 2026, 10:42 PM EDT
Active, not recruiting No phase listed Observational

An Open Label 100 Person Study Evaluating a Natural Supplement for Weight Loss and Fat Loss.

NCT07152470
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Diet and Exercise Tracking
Behavioral
Lead sponsor
Prostasis, LLC, dba Tonum Health
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Timeline
2025
U.S. locations
1
States / cities
West Palm Beach, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2025 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Not applicable Interventional Results available

Adaptation of a Digital Weight Loss Intervention Promoting Self-regulation for Use in Type 2 Diabetes

NCT03650088
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Overweight and Obesity
Interventions
Behavioral weight loss with digital tools
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 13, 2023 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Family-Based Weight Loss Intervention for Youth With Intellectual Disability

NCT02033642
View directory record Official record
Conditions
Obesity
Interventions
Family Based Behavioral Intervention, Maintenance
Behavioral
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
14 Years to 22 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Oct 14, 2026, 10:42 PM EDT
Not listed Not applicable Interventional

Prevacid vs Lifestyle Modifications for the Treatment of LPR

NCT00274339
View directory record Official record
Conditions
Laryngopharyngeal Reflux
Interventions
Prevacid 30mg BID, Lifestyle changes of exercise and diet changes for weight loss and avoidance of reflux inducing foods.
Drug · Behavioral
Lead sponsor
Hodge, Kenneth M., M.D.
Individual
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 25, 2007 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healthy Living Partnerships to Prevent Diabetes in Veterans Pilot Study

NCT02835495
View directory record Official record
Conditions
Pre-diabetes, Obesity
Interventions
HELP Vets Intervention, Individual Education Program
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Salisbury, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2020 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CALERIE (PBRC, Baton Rouge) - Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy

NCT00099151
View directory record Official record
Conditions
Aging, Cardiovascular Disease, Diabetes Mellitus
Interventions
Caloric Restriction (CR), Exercise
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
25 Years to 50 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2006
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 11, 2009 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Not applicable Interventional Results available

Look AHEAD: Action for Health in Diabetes

NCT00017953
View directory record Official record
Conditions
Diabetes, Myocardial Infarction, Stroke, Kidney Diseases, Bone Diseases, Dyslipidemia
Interventions
Lifestyle Intervention, Diabetes Support and Education
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years to 76 Years
Enrollment
5,145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2020
U.S. locations
18
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 14 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Not applicable Interventional

Project THRIVE: Evaluating Different Approaches to Dietary Self-Monitoring for Weight Loss

NCT05241353
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Reduced Frequency Self-Monitoring, Full-Frequency Self-Monitoring, Standard Behavioral Treatment
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 75 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 31, 2023 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fit and Trim for Diabetes Prevention

NCT02278939
View directory record Official record
Conditions
Pre-diabetes, Overweight, Obese
Interventions
Filipinos Fit and Trim Weight Loss Program
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
24 Years to 80 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2018 · Synced Oct 14, 2026, 10:42 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Trial to Examine the Effects of a Weight Loss Program Emphasizing Protein, Dietary Fiber, and Exercise (30-30-30 Plan)

NCT07789769
View directory record Official record
Conditions
Overweight , Obesity
Interventions
30-30-30 PFE Intervention, Standard
Behavioral
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
18 Years to 69 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Addison, Illinois • Chicago, Illinois • Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Phase 4 Interventional Results available

A Toolbox Approach to Obesity Treatment in Primary Care

NCT01922934
View directory record Official record
Conditions
Obesity
Interventions
Commercial weight loss program, Colorado Weigh, Meal replacements, Obesity pharmacotherapy, Recreation center passes
Behavioral · Dietary Supplement · Drug
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years to 80 Years
Enrollment
4,730 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 18, 2017 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sleep Goal-focused Online Access to Lifestyle Support

NCT05942326
View directory record Official record
Conditions
Weight Loss, Weight, Body
Interventions
Sleep GOALS, Education
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Single Arm Trial of a Multi-component Commercial Digital Weight Loss Program

NCT04302389
View directory record Official record
Conditions
Weight Loss
Interventions
myWW App, Virtual Workshops, and Private Facebook Group
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 75 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 7, 2025 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors

NCT04221750
View directory record Official record
Conditions
Frailty, Sarcopenic Obesity, Aging
Interventions
Lifestyle therapy, Metformin Hydrochloride, Placebo, Healthy Lifestyle
Behavioral · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years to 85 Years
Enrollment
114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

UCSD Get Fit, Be Fit Study

NCT03387709
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Pistachio-enriched diet, General dietary guidance diet
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Not applicable Interventional Results available

Integrating Online Weight Management With Primary Care Support

NCT02656693
View directory record Official record
Conditions
Obesity
Interventions
Online weight management program, Population health management support
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
20 Years to 70 Years
Enrollment
840 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2020 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lifestyle Interventions for Seniors With Apnea

NCT01422863
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
60 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 18, 2017 · Synced Oct 14, 2026, 10:42 PM EDT
Completed Not applicable Interventional

Motivational Interviewing for Weight Loss With Young Adults

NCT01899625
View directory record Official record
Conditions
Obesity
Interventions
Brief Behavioral Weight Loss (BWL), Motivation Enhanced BWL
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 25 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 26, 2016 · Synced Oct 14, 2026, 10:42 PM EDT