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ClinicalTrials.gov public records Last synced Oct 4, 2026, 10:06 PM EDT

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Showing 73–96 of 543 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Exercise and Dietary Weight Loss Clear all
Recruiting Phase 4 Interventional

Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease

NCT07058155
View directory record Official record
Conditions
Liver Cirrhoses, Portal Hypertension Related to Cirrhosis, Severe Obesity, TIPS
Interventions
Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect), Lifestyle Counseling - Diet & Physical-Activity Program
Procedure · Drug · Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2034
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 4, 2026, 10:06 PM EDT
Completed Not applicable Interventional Results available

Empowered With Movement to Prevent Obesity and Weight Regain

NCT02923674
View directory record Official record
Conditions
Obesity, Weight Loss, Sedentary Lifestyle
Interventions
Weight loss, Exercise, Sitless
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
65 Years to 85 Years
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 23, 2022 · Synced Oct 4, 2026, 10:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fatty Acid Metabolism and Insulin Sensitivity: the Role of Endurance Exercise

NCT00795860
View directory record Official record
Conditions
Insulin Resistance and Type 2 Diabetes
Interventions
Weight loss - diet only, Weight loss plus exercise
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 16, 2017 · Synced Oct 4, 2026, 10:06 PM EDT
Withdrawn Not applicable Interventional

Validation of a Personal Breath Analyzer for Diet and Energy Expenditure Assessment and Management

NCT02981160
View directory record Official record
Conditions
Obesity
Interventions
Dietary
Other
Lead sponsor
Banner Health
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Gilbert, Arizona • Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 4, 2026, 10:06 PM EDT
Completed Not applicable Interventional

Cooperative Lifestyle Programs (CLIP-II)

NCT01547182
View directory record Official record
Conditions
Cardiovascular Disease, Obesity, Physical Disability
Interventions
Caloric restriction, Aerobic Training, Resistance Training
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years to 79 Years
Enrollment
249 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
3
States / cities
Kernersville, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 4, 2026, 10:06 PM EDT
Completed Not applicable Interventional

Virtual Mindfulness and Weight Management to Mitigate Risk of Relapse and Improve Wellbeing in Cancer Survivors

NCT06030427
View directory record Official record
Conditions
Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm, Obesity-Related Malignant Neoplasm
Interventions
Behavioral Dietary Intervention, Educational Intervention, Health Promotion and Education, Internet-Based Intervention, Interview, Medical Device Usage and Evaluation, Mindfulness Relaxation, Physical Performance Testing, Questionnaire Administration
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
La Crosse, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 24, 2025 · Synced Oct 4, 2026, 10:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Barriers to Effective Weight Loss in Overweight Adolescents

NCT00562263
View directory record Official record
Conditions
Overweight
Interventions
Lifestyle modification
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
11 Years to 18 Years · Female only
Enrollment
257 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2013
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 31, 2014 · Synced Oct 4, 2026, 10:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Inhibitory Control and Pediatric Weight Management

NCT04747548
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Kurbo Only, Kurbo + PolyRules!
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
7 Years to 13 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2022 · Synced Oct 4, 2026, 10:06 PM EDT
Not listed Not applicable Interventional

Roux-en-Y-Gastric Bypass vs. Lifestyle Modification and Medical Therapy in the Treatment of Type 2 Diabetes

NCT01231308
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Roux-en-Y-Gastric Bypass, Intensive lifestyle modification and Optimal medical Therapy
Procedure · Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
21 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 24, 2012 · Synced Oct 4, 2026, 10:06 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Remote Approaches for Optimizing Weight Loss (Elevate Weight Loss Trial)

NCT06875622
View directory record Official record
Conditions
Obesity/therapy
Interventions
Automated online weight loss program, Individual coaching, Group-based, videoconference-delivered weight loss
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
490 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 4, 2026, 10:06 PM EDT
Not listed Not applicable Interventional

Creating an Optimized Technology-Based Weight Loss Program for Cardiac Rehabilitation Patients

NCT03845283
View directory record Official record
Conditions
Cardiovascular Diseases, Obesity
Interventions
Online Behavioral Weight Loss Program, Physical Activity Intervention, Bite Counter, Virtual Reality, Virtual Meetings
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
21 Years to 75 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 4, 2026, 10:06 PM EDT
Recruiting Not applicable Interventional

EMPOWER: Effects of Weight Loss and Exercise Post-stroke

NCT05901675
View directory record Official record
Conditions
Obesity, Stroke
Interventions
Lifestyle Management Program, Post-stroke Optimization of Walking using Explosive Resistance
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
35 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 4, 2026, 10:06 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Healthy Living After Knee Replacement

NCT05190666
View directory record Official record
Conditions
Arthroplasty, Overweight and Obesity
Interventions
PACE Weight Loss program, Chronic Disease Self-Management
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
Not listed
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 4, 2026, 10:06 PM EDT
Completed Phase 2 Interventional

A Comparison of Postprandial Glucose After a MMTT, and the Metabolic Effects of Insulin Withdrawal in a Crossover Study in Subjects With Type 1 Diabetes

NCT04956263
View directory record Official record
Conditions
Diabetes, Diabetes Mellitus, Type 1, Type1diabetes, Diabetes Mellitus
Interventions
YG1699, Dapagliflozin
Drug
Lead sponsor
Youngene Therapeutics Inc., Ltd.
Industry
Eligibility
18 Years to 60 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chula Vista, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2022 · Synced Oct 4, 2026, 10:06 PM EDT
Completed Not applicable Interventional

Collaborate and Leverage Evidence in African American Rural Network

NCT06730633
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Heart Matters
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
9
States / cities
Enfield, North Carolina • Nashville, North Carolina • Rocky Mount, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 4, 2026, 10:06 PM EDT
Recruiting Not applicable Interventional

Weight Loss and ExeRcise for Post-stroke Veterans

NCT06322030
View directory record Official record
Conditions
Stroke
Interventions
FOCUS-15 Lifestyle Management Program, Exercise Training
Dietary Supplement · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 80 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 4, 2026, 10:06 PM EDT
Completed Not applicable Interventional

A Feasibility Study for the Treatment of Primary Obesity Cross-over Arm

NCT05939973
View directory record Official record
Conditions
Obesity, Primary
Interventions
g-Cath EZ Delivery Catheter with Snowshoe Suture Anchors
Device
Lead sponsor
USGI Medical
Industry
Eligibility
22 Years to 60 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 4, 2026, 10:06 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Effect of GLP-1 Receptor Agonism After Sleeve Gastrectomy

NCT03115424
View directory record Official record
Conditions
Obesity
Interventions
Saxenda, Placebos, RYGB
Drug · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 27, 2024 · Synced Oct 4, 2026, 10:06 PM EDT
Completed Not applicable Interventional Results available

Pragmatic Obstructive Sleep Apnea Weight Loss Trial Assessing Effectiveness and Reach

NCT05104450
View directory record Official record
Conditions
Obesity, Sleep Apnea, Obstructive
Interventions
lifestyle intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
696 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 4, 2026, 10:06 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Examining Valence-based Effects in Self-Monitoring Feedback Messages

NCT07292389
View directory record Official record
Conditions
Obesity & Overweight, Obesity (Disorder)
Interventions
Positive Reinforcement, Positive Reinforcement + Areas for Change
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 4, 2026, 10:06 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Strategies for Improving Remote-based Weight Loss (PATH Trial)

NCT06166225
View directory record Official record
Conditions
Obesity
Interventions
Internet-based weight loss program, Yoga, Health and Wellness
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 4, 2026, 10:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Behavioral Weight Loss as a Treatment for Migraine in Obese Women

NCT01197196
View directory record Official record
Conditions
Migraine, Obesity
Interventions
Behavioral Weight Loss Intervention, Migraine Education
Behavioral · Other
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 31, 2021 · Synced Oct 4, 2026, 10:06 PM EDT
Completed Not applicable Interventional

Lifestyle Intervention for Treatment of Diabetes

NCT01806727
View directory record Official record
Conditions
Type 2 Diabetes, Overweight, Obesity
Interventions
Community Lifestyle Weight Loss (LWL), Diabetes Self Management (DSM)
Behavioral
Lead sponsor
Wake Forest University
Other
Eligibility
21 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2018 · Synced Oct 4, 2026, 10:06 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Diet and Meal Timing in Patients With Metabolic Dysfunction Associated Steatoic Liver Disease

NCT05332613
View directory record Official record
Conditions
Non-Alcoholic Fatty Liver Disease
Interventions
TRE plus SOC, SOC, TRE
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 4, 2026, 10:06 PM EDT