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Showing 1–24 of 609 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Exercise and diet education and instruction Clear all
Completed Not applicable Interventional

Frequency Needed for School-based Obesity Intervention

NCT03797105
View directory record Official record
Conditions
Obesity, Child
Interventions
School-Based Obesity Intervention (FLOW)
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
10 Years to 17 Years
Enrollment
243 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Leisure Time Activity and Nutrition Program

NCT00656045
View directory record Official record
Conditions
Obesity, Physical Activity
Interventions
Dietary, Physical Activity, TV Watching
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
21 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional

Exercise and Weight Loss for Improving Mobility in Older Adults Who Are Obese

NCT00119795
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Metabolic Syndrome X, Obesity
Interventions
Exercise, Weight Loss, Health Education Control
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
60 Years to 79 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
3
States / cities
Greensboro, North Carolina • Lexington, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional

Preventing Amputations by Tailored Risk-based Intervention to Optimize Therapy

NCT02356757
View directory record Official record
Conditions
Diabetes, Foot Ulcer
Interventions
Personalized Behavioral Intervention, Current Best Practice
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years and older
Enrollment
406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2021 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional Results available

Pivotal Aspiration Therapy With Adjusted Lifestyle Therapy Study

NCT01766037
View directory record Official record
Conditions
Obesity
Interventions
Aspiration Therapy (AspireAssist), Lifestyle Therapy
Device · Behavioral
Lead sponsor
Aspire Bariatrics, Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
10
States / cities
San Diego, California • Washington D.C., District of Columbia • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2020 · Synced Sep 28, 2026, 5:13 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Lifestyle Interventions for Long Term Diabetes Control

NCT00364312
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
diet and physical activity
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
390 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 14, 2006 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Alcohol Use Reduction in Methadone Individuals With Hepatitis C Virus(HCV)

NCT00958763
View directory record Official record
Conditions
Hepatitis C
Interventions
Motivational Interviewing, Single - MIS, Motivational Interviewing Group, Usual Care Group - UCG
Behavioral · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 55 Years
Enrollment
219 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
3
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2009 · Synced Sep 28, 2026, 5:13 PM EDT
Recruiting Phase 2 Interventional

Efficacy of Cognitive Behavioral Therapy for Insomnia to Treat Insomnia Symptoms in Individuals With Multiple Sclerosis

NCT06428006
View directory record Official record
Conditions
Multiple Sclerosis, Insomnia
Interventions
Cognitive behavioral therapy for insomnia, Sleep and lifestyle education
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Encourage Healthy Families

NCT01823367
View directory record Official record
Conditions
Gestational Diabetes Mellitus, Pre-diabetes
Interventions
Diabetes Prevention Program (DPP)
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
8 Years and older
Enrollment
335 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 24, 2017 · Synced Sep 28, 2026, 5:13 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Online Mindfulness-Based College for Young Adults

NCT04733300
View directory record Official record
Conditions
Depressive Symptoms, Loneliness, Sedentary Behavior, Mindfulness, Physical Activity, Diet, Sleep, Emotional Regulation, Alcohol Consumption, Youth, Stress, Psychological
Interventions
Mindfulness-Based College for Young Adults, Health Education for Young Adults
Behavioral · Other
Lead sponsor
Eric Loucks
Other
Eligibility
18 Years to 29 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sustainable Culturally Adapted Nutrition (SCAN) Program

NCT07220057
View directory record Official record
Conditions
Diabetes
Interventions
Live instructional video sessions, Links to educational videos, Diabetes Prevention Program (DPP), Produce Delivery
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial of an Integrated Clinic-community Intervention in Children and Adolescents With Obesity (Hearts and Parks)

NCT03339440
View directory record Official record
Conditions
Childhood Obesity, Pediatric Obesity, Quality of Life, Cardiovascular Risk Factor
Interventions
Hearts & Parks
Behavioral
Lead sponsor
Duke University
Other
Eligibility
5 Years to 18 Years
Enrollment
327 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
3
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional Results available

Patient and Provider Interventions for Managing Osteoarthritis in Primary Care

NCT01130740
View directory record Official record
Conditions
Osteoarthritis
Interventions
Osteoarthritis Intervention
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2015 · Synced Sep 28, 2026, 5:13 PM EDT
Not yet recruiting Phase 4 Interventional

Nutrition Intervention Combined With Resmetirom for MASH

NCT07680478
View directory record Official record
Conditions
Metabolic Dysfunction-Associated Steatohepatitis (MASH)
Interventions
Resmetirom therapy, Comprehensive nutritional intervention, Standard dietary support
Drug · Behavioral
Lead sponsor
City University of New York
Other
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 28, 2026, 5:13 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Reducing Obesity Through Play Among Toddlers: Tiny Steps to Health (TSHS) Study

NCT06918821
View directory record Official record
Conditions
Childhood Obesity
Interventions
Healthy Toddler Parent Group (HTPG), Families Understanding Nutrition and Physically Active Lifestyles (FUNPALs) Playgroup
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Months to 36 Months
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional

A System for Preference Assessment in Mental Health

NCT02183844
View directory record Official record
Conditions
Mental Disorders, Schizophrenia, Overweight, Obesity
Interventions
Psychosocial Weight Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 28, 2026, 5:13 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks

NCT05674799
View directory record Official record
Conditions
Overweight or Obesity
Interventions
NDPP-NextGen
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 39 Years · Female only
Enrollment
403 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional Results available

Community-based Brain Health Program to Address Dementia Risk

NCT05529706
View directory record Official record
Conditions
Dementia, Alzheimer Disease
Interventions
Brain Health Program
Other
Lead sponsor
Posit Science Corporation
Industry
Eligibility
65 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional

OPTIMIzing muScle Preservation in paTients wIth Cirrhosis

NCT05367596
View directory record Official record
Conditions
Obesity, Compensated Cirrhosis, Sarcopenia
Interventions
Continuous Energy Restriction (CER), Alternate Day Modified Fasting (ADMF), Group Health Education Sessions, Late Evening Snack, Physical activity, Self-monitoring, Remotely Supervised Exercise Sessions
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Ecological Approach to Addressing Childhood Obesity Issues in Imperial County

NCT02197390
View directory record Official record
Conditions
Childhood Obesity
Interventions
Family wellness workshops, Obesity chronic care model, Physical activity, healthy eating, water drinking, healthy sleep promotion, Environment, policy, systems changes in clinic setting only, No intervention, Environment, policy, and systems changes in schools, early child care education & recreation
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
2 Years to 11 Years
Enrollment
1,184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2021
U.S. locations
2
States / cities
El Centro, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional

Improving Outcomes for Hemodialysis Patients

NCT03395366
View directory record Official record
Conditions
Quality of Life, End Stage Renal Disease
Interventions
Multifaceted Educational / Cognitive Behavioral Intervention
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2022 · Synced Sep 28, 2026, 5:13 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

PGC-1 & Muscle Mitochondrial Dysfunction in Diabetes

NCT02282423
View directory record Official record
Conditions
Diabetes, Obesity
Interventions
Pre-study dietary and exercise instruction., Screening examination and oral glucose tolerance test, Euglycemic clamp, VO2max., Acute exercise bout, Percutaneous needle muscle biopsies
Behavioral · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
30 Years to 59 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated May 11, 2016 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional Results available

Feasibility of a Campaign Intervention Compared to a Standard Behavioral Weight Loss Intervention in Overweight and Obese Adults

NCT01803737
View directory record Official record
Conditions
Weight Loss
Interventions
Standard Behavioral Weight Loss Intervention (SBWL), Campaign Intervention (CI)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 16, 2014 · Synced Sep 28, 2026, 5:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Outcomes in Women With Gestational Diabetes Mellitus and Their Infants

NCT01809431
View directory record Official record
Conditions
Gestational Diabetes
Interventions
Intervention
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
2
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Sep 28, 2026, 5:13 PM EDT