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Showing 1–24 of 819 matching trials from the live ClinicalTrials.gov search.
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Terminated Phase 3 Interventional

Effect of 2-year Administration of CP-945,598 on Weight Loss Efficacy and Safety.

NCT00396448
View directory record Official record
Conditions
Obesity
Interventions
CP-945,598 Treatment B, CP-945,598 Treatment A, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 70 Years
Enrollment
1,253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
15
States / cities
Peoria, Arizona • Newport Beach, California • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2012 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutrition, Exercise, and Technology for Weight Loss

NCT02731768
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Standard, Social support-enhanced, Fitbit Zip, Digital body weight scale
Behavioral · Device
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Phase 2Phase 3 Interventional

Delivering an Evidence-Based Lifestyle Intervention Via the Internet: A Randomized Controlled Study

NCT01043718
View directory record Official record
Conditions
Obesity
Interventions
More-Intensive, Less-Intensive
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Not applicable Interventional

Changing Healthy Outcomes In Clinic Environments

NCT00674518
View directory record Official record
Conditions
Obesity, Physical Inactivity, Diabetes
Interventions
One on one counseling, Group/team - based health education, PACE physician counseling
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
30 Years to 65 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Sep 3, 2026, 12:06 AM EDT
Terminated Not applicable Interventional Results available

Diet and Exercise Program to Promote Weight Loss and Improve Health in Men With Low- or Low-Intermediate-Risk Prostate Cancer

NCT02454517
View directory record Official record
Conditions
Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC V7, Stage IIA Prostate Cancer AJCC v7
Interventions
Behavioral Dietary Intervention, Exercise Intervention, Informational Intervention, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Questionnaire Administration
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
40 Years and older · Male only
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 3, 2023 · Synced Sep 3, 2026, 12:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Pilot Factorial Trial of an Integrated Lifestyle Intervention

NCT06116435
View directory record Official record
Conditions
Physical Inactivity, Overweight and Obesity
Interventions
Prevent T2, Move group-based classes, Fitness Membership, Mental Imagery, Move 1:1 Support
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Phase 2 Interventional

The Comparison of a Technology-Based System and an In-Person Behavioral Weight Loss Intervention

NCT01134874
View directory record Official record
Conditions
Obesity
Interventions
Standard weight loss intervention, Standard weight loss intervention plus technology, Technology only
Behavioral
Lead sponsor
John M. Jakicic, PhD
Other
Eligibility
18 Years to 55 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Calorie Restriction and Changes in Body Composition, Disease, Function, and Quality of Life in Older Adults

NCT00955903
View directory record Official record
Conditions
Obesity, Diabetes, Hypertension, Hyperlipidemia
Interventions
Exercise, Reduced Calorie Diet, Weight Maintenance Diet
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
65 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 4, 2017 · Synced Sep 3, 2026, 12:06 AM EDT
Terminated Not applicable Interventional Results available

Multimodal Treatment Strategy for Cancer Cachexia

NCT00625742
View directory record Official record
Conditions
Advanced Cancer, Cachexia
Interventions
Graded Resistance Training, Aerobic Exercise, Melatonin, Juven, Atenolol, Ibuprofen
Behavioral · Drug · Dietary Supplement
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2016 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Phase 3 Interventional

Lifestyle, Exercise and Nutrition Study 1

NCT02109068
View directory record Official record
Conditions
Breast Cancer, Weight Loss
Interventions
Weight Loss Counseling- Phone, Weight Loss Counseling- In-Person
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 8, 2014 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Remote Intervention for Diet and Exercise (RIDE)

NCT00883350
View directory record Official record
Conditions
Overweight, Obesity
Interventions
RIDE e-health application
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 2, 2024 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Not applicable Interventional

Early Detection of Diastolic Dysfunction and the Role of Lifestyle Measures in Its Treatment

NCT00998114
View directory record Official record
Conditions
Diastolic Dysfunction
Interventions
Exercise
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
40 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 4, 2016 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Not applicable Interventional

Impact of Fitbit Plus Weight Management Program on Physical Activity and Metabolic Disease in Obese Adolescents

NCT02507791
View directory record Official record
Conditions
Obesity
Interventions
Fitbit Charge HR plus weekly phone calls to review physical activity data
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
7 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 14, 2022 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Not applicable Interventional Results available

The Effects of Obesity and Obstructive Sleep Apnea on Inflammation and Heart Disease

NCT00371293
View directory record Official record
Conditions
Sleep Apnea Syndromes, Inflammation
Interventions
Weight Loss Program, CPAP therapy
Behavioral · Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Internet Assisted Obesity Treatment Enhanced With Financial Incentives

NCT02688621
View directory record Official record
Conditions
Obesity
Interventions
Internet Only, Internet + Incentives
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
418 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
2
States / cities
Columbia, South Carolina • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Phase 2 Interventional

Innovative Approaches to Diet, Exercise and Activity

NCT01131871
View directory record Official record
Conditions
Body Weight
Interventions
Standard Behavioral Weight Loss Intervention, Enhanced Weight Loss Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 35 Years
Enrollment
471 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Not applicable Interventional

BfedBwell Proof-of-Concept Pilot

NCT06191666
View directory record Official record
Conditions
Cancer Survivorship, Obesity, Overweight
Interventions
Group-based education and discussion, Individual 1:1 counseling, Group based behavioral skills development and cooking demonstrations, BfitBwell
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 3, 2026, 12:06 AM EDT
Recruiting Phase 3 Interventional

A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

NCT07481630
View directory record Official record
Conditions
Obesity, Knee Osteoarthritis (OA)
Interventions
NNC0487-0111, Placebo (matched to NNC0487-0111 )
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
19
States / cities
Phoenix, Arizona • Walnut Creek, California • Hamden, Connecticut + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Not applicable Interventional

Lifestyle Intervention to Improve Bone Quality

NCT03329963
View directory record Official record
Conditions
Aging, Obesity
Interventions
Healthy Lifestyle Intervention, Lifestyle Intervention
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
65 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Sep 3, 2026, 12:06 AM EDT
Completed No phase listed Observational

Gene x Behavior Interaction in the Look AHEAD Study

NCT01270763
View directory record Official record
Conditions
Obesity, Type 2 Diabetes
Interventions
Intensive lifestyle intervention, Diabetes support and education
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
45 Years to 74 Years
Enrollment
4,108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 17, 2015 · Synced Sep 3, 2026, 12:06 AM EDT
Not listed Not applicable Interventional

Prevacid vs Lifestyle Modifications for the Treatment of LPR

NCT00274339
View directory record Official record
Conditions
Laryngopharyngeal Reflux
Interventions
Prevacid 30mg BID, Lifestyle changes of exercise and diet changes for weight loss and avoidance of reflux inducing foods.
Drug · Behavioral
Lead sponsor
Hodge, Kenneth M., M.D.
Individual
Eligibility
18 Years and older
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 24, 2007 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Not applicable Interventional

Lifestyle Intervention Trial in Obese Elderly

NCT01065636
View directory record Official record
Conditions
Obesity
Interventions
Diet + Resistance Training, Diet + Aerobic Training, Diet + Resistance/Aerobic Exercise
Behavioral
Lead sponsor
Biomedical Research Institute of New Mexico
Other
Eligibility
65 Years to 85 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
2
States / cities
Albuquerque, New Mexico • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sustainability of MOVE UP Lifestyle Intervention

NCT03963830
View directory record Official record
Conditions
Body Weight, Diet, Healthy, Physical Disability
Interventions
MOVE UP
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 1, 2021 · Synced Sep 3, 2026, 12:06 AM EDT
Completed Not applicable Interventional

Weight Inclusive and Adaptive Strategies to Enhance Cardiometabolic Health in Black Adults

NCT06284681
View directory record Official record
Conditions
Obesity, Prehypertension, Hypertension, PreDiabetes, Type 2 Diabetes, Dyslipidemia
Interventions
Weight-focused health coaching, Weight-neutral health coaching, Intensify lifestyle approach, Augment with enhanced medical management
Behavioral · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 3, 2026, 12:06 AM EDT