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Showing 1–24 of 153 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Exoskeleton Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Enhancing Voluntary Motion in Broad Patient Populations With Modular Powered Orthoses Renewal

NCT07673328
View directory record Official record
Conditions
Lower-limb Orthoses, Osteoarthritic Knee Pain, Osteoarthritis (OA) of the Knee
Interventions
Modular powered orthosis
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 85 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Sep 4, 2026, 10:04 AM EDT
Enrolling by invitation Not applicable Interventional

Neuromechanical Mechanisms of Exosuit-assisted Gait Rehabilitation After Stroke

NCT07218094
View directory record Official record
Conditions
Stroke
Interventions
Walking with robotic ankle assistance
Device
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 4, 2026, 10:04 AM EDT
Recruiting Not applicable Interventional

Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders

NCT05726591
View directory record Official record
Conditions
Cerebral Palsy, Muscular Dystrophy, Spina Bifida, Incomplete Spinal Cord Injury
Interventions
EA-KAFO
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
3 Years to 17 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 4, 2026, 10:04 AM EDT
Not yet recruiting Not applicable Interventional

Modulating Locomotor-Respiratory Coupling Through Adaptive Exoskeleton Assistance in Patients With COPD

NCT07703527
View directory record Official record
Conditions
COPD (Chronic Obstructive Pulmonary Disease)
Interventions
Hip Exoskeleton-Assisted Walking
Device
Lead sponsor
University of Nebraska
Other
Eligibility
45 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 4, 2026, 10:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Human-Machine System for the H2 Lower Limb Exoskeleton

NCT02114450
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Robot-assisted training with the H2 lower limb powered exoskeleton, Supervised motor practice
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2029
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 29, 2024 · Synced Sep 4, 2026, 10:04 AM EDT
Completed Not applicable Interventional

A Comparison of Conventional Physical Therapy, Powered Exoskeleton, and Hybrid Physical Therapy With Exoskeleton

NCT04648878
View directory record Official record
Conditions
Stroke
Interventions
Hybrid combination of physical therapy and powered exoskeleton, Powered Exoskeleton Only, Physical Therapy only
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Sep 4, 2026, 10:04 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Exoskeleton Use With In Home Functional Activities

NCT06222398
View directory record Official record
Conditions
Paraplegia
Interventions
Exoskeleton
Device
Lead sponsor
A.T. Still University of Health Sciences
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Mesa, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 4, 2026, 10:04 AM EDT
Completed Phase 2 Interventional Results available

Neuromodulation Techniques After SCI

NCT04241250
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
EAW+SCES (exoskelton and spinal cord epidural stimulation), EAW+TS (exoskelton and transspinal stimulation)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years · Male only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 4, 2026, 10:04 AM EDT
Withdrawn Not applicable Interventional

Does Supplementing of Quadriceps Strength With Exoskeleton After Total Knee Arthroplasty in High Risk Population Reduce Transfer to Extended Care Facility (ECF)

NCT03762603
View directory record Official record
Conditions
Primary Knee Replacement Surgery
Interventions
Robotic exoskeleton device
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Sep 4, 2026, 10:04 AM EDT
Completed Not applicable Interventional Results available

Exoskeletal-Assisted Walking in SCI Acute Inpatient Rehabilitation

NCT04221373
View directory record Official record
Conditions
Spinal Cord Injuries, Inpatient
Interventions
Ekso™ powered exoskeleton, Standard of care
Device · Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 25, 2023 · Synced Sep 4, 2026, 10:04 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Exoskeleton Variability Optimization

NCT04338815
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Exoskeleton Optimization, Endurance Evaluation
Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 85 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Sep 4, 2026, 10:04 AM EDT
Not listed Not applicable Interventional

Non-Ambulatory SCI Walk Using a Robotic Exoskeleton: Effect on Bone and Muscle

NCT02324322
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Exoskeleton Training, Muscle Biopsies, MRI
Device · Other
Lead sponsor
Kessler Foundation
Other
Eligibility
21 Years to 45 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 21, 2017 · Synced Sep 4, 2026, 10:04 AM EDT
Completed Not applicable Interventional Results available

Robotics For Rehabilitation Therapy: Functional Versus Individual Joint Training

NCT01050231
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
Functional/ Multi-joints activities, Individual Joint Training
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 73 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2021 · Synced Sep 4, 2026, 10:04 AM EDT
Completed Not applicable Interventional Results available

Exoskeleton Treatment of Deconditioning Due to Limited Ambulation Caused by Illness or Injury

NCT03355755
View directory record Official record
Conditions
Debility Due to Disease
Interventions
EksoGT with SmartAssist software
Device
Lead sponsor
Ekso Bionics
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
3
States / cities
Wallingford, Connecticut • Wheaton, Illinois • Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Sep 4, 2026, 10:04 AM EDT
Completed Not applicable Interventional Results available

Muscle Synergies During Gait in Children With Cerebral Palsy Undergoing Robot-assisted Gait Therapy

NCT06156969
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Robot-Assisted Gait Training
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
6 Years to 18 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Sep 4, 2026, 10:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Soleus Loading Response During Walking

NCT05436366
View directory record Official record
Conditions
Healthy, Spastic Hemiparesis, Stroke
Interventions
Soleus loading response in able-bodied participants, Soleus loading response in participants with hemiparesis
Device
Lead sponsor
Victor H. Duenas
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Nov 28, 2024 · Synced Sep 4, 2026, 10:04 AM EDT
Completed Phase 1Phase 2 Interventional

Effect of Robot-assisted Training on Foot Drop in Multiple Sclerosis

NCT00872053
View directory record Official record
Conditions
MS (Multiple Sclerosis)
Interventions
Anklebot, Lokomat
Device
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 19, 2013 · Synced Sep 4, 2026, 10:04 AM EDT
Recruiting Not applicable Interventional

Exoskeleton for Balance

NCT07356011
View directory record Official record
Conditions
Stroke
Interventions
No Exoskeleton, Exoskeleton (zero impedance), Exoskeleton (low impedance), Exoskeleton (medium impedance), Exoskeleton (high impedance)
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 4, 2026, 10:04 AM EDT
Recruiting Not applicable Interventional

Effects of Exoskeleton-Assisted Gait Training on Functional Rehabilitation Outcomes in Patients With Stroke

NCT03980457
View directory record Official record
Conditions
Stroke, Weakness of Extremities as Sequela of Stroke
Interventions
Indego Exoskeleton, Standard Rehabilitation
Device · Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Sep 4, 2026, 10:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brain Machine Interface Control of an Robotic Exoskeleton in Training Upper Extremity Functions in Stroke

NCT01948739
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
MAHI EXO-II exoskeleton augmented with BMI system
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Sep 4, 2026, 10:04 AM EDT
Completed Not applicable Interventional Results available

The ReWalk Exoskeletal Walking System for Persons With Paraplegia

NCT01454570
View directory record Official record
Conditions
Paraplegia
Interventions
powered exoskeleton
Device
Lead sponsor
James J. Peters Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 24, 2020 · Synced Sep 4, 2026, 10:04 AM EDT
Enrolling by invitation No phase listed Observational

Health and Financial Impact on the Use of a Personal Exoskeleton in the Home and Community: a Case Study

NCT07030322
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Overground Robotic Exoskeleton
Device
Lead sponsor
Ekso Bionics
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Rafael, California
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Sep 4, 2026, 10:04 AM EDT
Not listed Not applicable Interventional

Evaluation of the Effectiveness and Safety of Keeogo™ Dermoskeleton in Subjects With Mobility Impairments Due to Stroke

NCT03986320
View directory record Official record
Conditions
Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Hemiparesis, Cerebral Vascular Accident
Interventions
Keeogo™ Dermoskeleton
Device
Lead sponsor
B-Temia, Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
Chicago, Illinois • West Orange, New Jersey • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 28, 2019 · Synced Sep 4, 2026, 10:04 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Improving Balance and Energetics of Walking Using a Hip Exoskeleton

NCT05447884
View directory record Official record
Conditions
Stroke
Interventions
A zero impedance mode, controlling a wearable bilateral hip exoskeleton, A personalized optimal assistance mode, controlling a wearable bilateral hip exoskeleton, A free walking mode, without wearing a wearable bilateral hip exoskeleton
Other
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 64 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 19, 2023 · Synced Sep 4, 2026, 10:04 AM EDT