Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 7, 2026, 5:01 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 98 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Exparel infiltration Clear all

Conditions: Acute Pain, Surgery, Regional Anesthesia
Interventions: Epidural, TAP Block; Drug
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Gynecologic Cancer, Post Operative Pain
Interventions: Bupivacaine, liposomal bupivacaine; Drug
Lead sponsor: Abington Memorial Hospital; Other
Eligibility: 18 Years to 99 Years · Female only
Enrollment: 128 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Abington, Pennsylvania

Conditions: Postsurgical Pain, Analgesia, Prostatectomy
Interventions: EXPAREL 20 mL, EXPAREL 40 mL; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years to 75 Years · Male only
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 1
States / cities: Brighton, Massachusetts

Conditions: Postoperative Pain, Shoulder Arthritis
Interventions: Liposomal Bupivacaine Infiltration, Continuous Perineural Ropivicaine Infusion; Drug
Lead sponsor: Eric Shepard; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Hip Fractures
Interventions: Exparel, Sodium Chloride; Drug
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 55 Years and older
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Lexington, Kentucky • Worcester, Massachusetts

Conditions: Post Operative Pain, Gynecologic Cancer
Interventions: Liposomal bupivacaine, Bupivacain; Drug
Lead sponsor: Tufts Medical Center; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pain, Postoperative
Interventions: Depobupivacaine, OnQ pump, 0.25% Bupivacaine; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older · Female only
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Lung Cancer
Interventions: Bupivacaine, Bupivacaine liposome; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 75 Years
Enrollment: 65 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 2
States / cities: New York, New York

Conditions: Postoperative Pain Management
Interventions: EXPAREL and Bupivacaine, Standard of Care; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 12
States / cities: New Haven, Connecticut • Boca Raton, Florida • Miami, Florida + 9 more

Conditions: Robotic Lung Surgery
Interventions: Intercostal nerve block and wound infiltration with liposomal bupivacaine, Intercostal nerve block and wound infiltration with bupivacaine/epinephrine + dexamethasone; Drug
Lead sponsor: Cooper Norcross Health; Other
Eligibility: 18 Years to 90 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Camden, New Jersey

Conditions: Knee Osteoarthritis
Interventions: liposomal bupivacaine, bupivacaine HCl, Ropivacaine, Saline; Drug
Lead sponsor: Texas Orthopaedics, Sports and Rehabilitation Associates; Other
Eligibility: 18 Years to 65 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Austin, Texas

Conditions: C-Section, Pain Management
Interventions: Exparel + Bupivacaine, Bupivacaine; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 186 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 12
States / cities: Loma Linda, California • Stanford, California • Boston, Massachusetts + 7 more

Conditions: Bowel Obstruction
Interventions: IV morphine sulfate, EXPAREL (bupivacaine liposome injectable suspension); Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Hip Injuries
Interventions: liposomal bupivacaine, Bupivacaine; Drug
Lead sponsor: Trinity Health Of New England; Other
Eligibility: 18 Years to 80 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2019
U.S. locations: 1
States / cities: Hartford, Connecticut

Conditions: Pain, Postoperative
Interventions: Liposomal bupivacaine, Placebo; Drug
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older · Female only
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Malignant Female Reproductive System Neoplasm
Interventions: Hydromorphone, Laparotomy, Liposomal Bupivacaine, Questionnaire Administration; Drug · Procedure · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years to 80 Years · Female only
Enrollment: 105 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Liposomal Bupivacaine
Interventions: Bupivacaine liposome injectable suspension; Drug
Lead sponsor: Case Western Reserve University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Pain
Interventions: EXPAREL, Placebo; Drug
Lead sponsor: Pacira Pharmaceuticals, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 13
States / cities: Winter Park, Florida • Savannah, Georgia • Chicago, Illinois + 10 more

Conditions: Pain, Postoperative, Pain, Acute Postoperative, Ankle Fractures, Ankle Injuries and Disorders
Interventions: Exparel, Peripheral Nerve Block; Drug
Lead sponsor: St. Luke's Hospital, Pennsylvania; Other
Eligibility: 18 Years and older
Enrollment: 248 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Bethlehem, Pennsylvania

Conditions: Trauma, Trauma Injury, Pain, Acute
Interventions: Bupivacaine Liposome Injection, Bupivacaine; Drug
Lead sponsor: Chadrick Evans; Other
Eligibility: 18 Years and older
Enrollment: 258 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Peoria, Illinois

Conditions: Arthritis
Interventions: Exparel, Saline; Drug · Other
Lead sponsor: Maimonides Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Nephrectomy
Interventions: Transverses Abdominis Plane (TAP) block, Quadratus Lumborum (QL) block, Surgeon Infiltration using Exparel; Procedure
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Tonsillectomy
Interventions: Adjunct Exparel (bupivacaine liposome suspension 1.3%), Standard Care; Drug · Other
Lead sponsor: Paul Hoff; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 2
States / cities: Ann Arbor, Michigan • Ypsilanti, Michigan

Conditions: Bupivacaine, Pain, Postoperative
Interventions: Bupivacaine, Liposomal bupivacaine, Placebos; Drug
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 18 Years and older · Female only
Enrollment: 132 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Fort Sam Houston, Texas

Search by objective public record fields.

Comparison of Epidural and TAP Block in Abdominal Surgery

A Comparison of Exparel to Bupivacaine in TAP Block for Abdominal Gynecologic Surgery

TAP-patients With Robotic Assisted Lap Prostatectomy

Liposomal Bupivacaine Infiltration vs Continuous Perineural Ropivacaine Infusion for Post-operative Pain After Total Shoulder Arthroplasty

Randomized Controlled Trial for Exparel Hip Fracture

Pilot: Intraoperative TAP Block and Post-operative Pain Control for Minimally Invasive Hysterectomy for Endometrial Cancer

Comparison of Local Anesthetic Infusion Pump Versus Depofoam Bupivacaine for Pain Management

Efficacy Between Serratus Plane Block And Local Infiltration In Vats

Phase 4 Study in Adult Subjects Undergoing Posterior Lumbar Spine Surgeries

Bupivacaine/Epinephrine +Dexamethasone vs. Liposomal Bupivacaine

Liposomal Bupivacaine vs Adductor Canal Block in Total Knee Arthroplasty

Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration Into the TAP vs. Bupivacaine Alone in Subjects Undergoing Elective C-Sections

A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302

Ultrasound Guided Local Infiltration Analgesia for Hip Arthroscopy

Liposomal Bupivacaine at Cesarean Delivery to Decrease Post-operative Pain

Liposomal Bupivacaine With or Without Hydromorphone for the Improvement of Pain Control After Laparotomy in Patients With Gynecological Malignancies

Exparel Versus Bupivacaine in Post-operative Pain Control

EXPAREL Administered by Infiltration Into the TAP for Prolonged Postsurgical Analgesia in Lower Abdominal Surgeries

Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery

Liposomal Bupivacaine Intercostal Nerve Block vs Thoracic Epidural for Regional Analgesia in Multiple Rib Fractures

Evaluation Exparel Delivered in Knee Replacement

Comparing 3 Different Types of Pain Blocks After Laparoscopic Nephrectomy

EXPAREL Post-tonsillectomy Clinical Trial

Wound Infiltration of Liposomal Bupivacaine v Plain Bupivacaine for Post-Op Pain Control in Elective Cesarean Delivery