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ClinicalTrials.gov public records Last synced Oct 2, 2026, 2:19 PM EDT

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Showing 25–41 of 41 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Experimental Mouthwash Clear all

Conditions: Cancer of Head and Neck, Mucositis Oral, Pharyngeal Mucositis
Interventions: Ketamine Topical; Drug
Lead sponsor: Northwell Health; Other
Eligibility: 18 Years to 70 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Lake Success, New York

Conditions: Tooth Stain
Interventions: Colgate® Regular Cavity Protection, Experimental Mouth Rinse, Crest® 3D White Multi-Care Whitening Rinse, Glamorous White, Fresh Mint; Drug · Other
Lead sponsor: Johnson & Johnson Consumer and Personal Products Worldwide; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 227 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Dentin Sensitivity
Interventions: Mouth Rinse, Fluoride Toothpaste, Potassium Nitrate Toothpaste; Device · Drug
Lead sponsor: Johnson & Johnson Consumer and Personal Products Worldwide; Industry
Eligibility: 18 Years and older
Enrollment: 153 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Diabetes Type 2, Periodontal Disease, Caries
Interventions: Diabetes Oral Health Program, Stannous Fluoride Dentifrice, Cetylpyridinium Chloride (CPC) and Zinc Lactate Mouthwash; Behavioral · Drug
Lead sponsor: Colgate Palmolive; Industry
Eligibility: 18 Years and older
Enrollment: 10,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Long Island City, New York

Conditions: Healthy
Interventions: Colgate Cavity Protection Toothpaste, Zero Alcohol Gum Prototype, Alcohol Gum Prototype, Listerine Cool Mint Antiseptic Mouthwash, 5% Hydroalcohol; Other
Lead sponsor: Johnson & Johnson Consumer Inc. (J&JCI); Industry
Eligibility: 18 Years and older
Enrollment: 192 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Gingivitis, Plaque
Interventions: Colgate® Cavity Protection Toothpaste, Listerine® Cool Mint®, Concept Curve Winter Series Toothbrush, 5% Hydroalcohol Mouthrinse, Mouthrinse Prototype 1, Mouthrinse Prototype 2; Other
Lead sponsor: Johnson & Johnson Consumer Inc. (J&JCI); Industry
Eligibility: 18 Years and older
Enrollment: 157 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Advanced Breast Cancer
Interventions: Dexamethasone based mouthwash, Everolimus, Exemestane; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 23
States / cities: Fayetteville, Arkansas • Anaheim, California • Los Angeles, California + 17 more

Conditions: Gingivitis
Interventions: vitamin D3, Placebo; Drug · Other
Lead sponsor: Boston University; Other
Eligibility: 18 Years to 64 Years
Enrollment: 35 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Malignant Neoplasm
Interventions: MK-1084, Pembrolizumab, Cetuximab, Sacituzumab tirumotecan (sac-TMT), Rescue medication; Drug · Biological
Lead sponsor: Merck Sharp & Dohme LLC; Industry
Eligibility: 18 Years and older
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2032
U.S. locations: 3
States / cities: Clermont, Florida • Fargo, North Dakota • Sioux Falls, South Dakota

Conditions: Dentin Sensitivity
Interventions: Experimental Oral Rinse 1, Experimental Oral Rinse 2, Placebo Oral Rinse, Standard fluoride toothpaste; Device · Other · Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 240 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Bronchial Aspiration
Interventions: Bed Head elevation, H2 blockers and mouth wash, Data collection for comparison; Other
Lead sponsor: Marshall University; Other
Eligibility: 18 Years and older
Enrollment: 159 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Huntington, West Virginia

Conditions: Dentin Sensitivity
Interventions: Experimental Oral Rinse 1 (1.5% w/w KOX, 0ppm F, pH 7.0), Experimental Oral Rinse 2 (2.0% w/w KOX, 45ppm F, pH 4.5), Placebo Oral Rinse (0% w/w KOX 0ppm F, pH 4.5 ); Other
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 221 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Plaque
Interventions: 3M™ Oral Rinse, Vehicle Control Oral Rinse, PerioShield™ Oral Health Rinse, Water; Device · Other
Lead sponsor: Solventum US LLC; Industry
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Xerostomia
Interventions: Biotene mouthwash, Mineral Water; Other
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Mucositis, Neoplasms
Interventions: Oral Defense Toothpaste, Crest Toothpaste, Magic Mouth Rinse; Drug
Lead sponsor: Oral Defense, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Spokane, Washington

Conditions: Dysphagia, GERD, Abdominal Pain
Interventions: Lidocaine, Placebo; Drug
Lead sponsor: Brooke Army Medical Center; Federal
Eligibility: 18 Years to 89 Years
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Fort Sam Houston, Texas

Conditions: Healthy
Interventions: Listerine Experimental Mouthwash, Colgate Cavity Protection Toothpaste, Listerine Total Care Zero, Listerine Cool Mint Zero; Drug · Other
Lead sponsor: Johnson & Johnson Consumer Inc. (J&JCI); Industry
Eligibility: 18 Years and older
Enrollment: 163 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Search by objective public record fields.

Efficacy of Ketamine Mouthwash in the Management of Oral and Pharyngeal Toxicity Associated With Head and Neck Chemoradiotherapy: A Phase 2, Simon 2-stage Trial

A Clinical Trial to Test the Effect of a Marketed Mouth Rinse on Stain Removal

A Test on a New Experimental Mouth Rinse for Relieving Tooth Sensitivity

Evaluate the Efficacy of an Oral Health Behavioral Intervention in People With Diabetes

A Twelve Week Study of Prototypes Mouth Rinses

Six Week Study of Experimental Mouth Rinses: Effect on Gingivitis and Plaque

Open-label, Phase II Study of Stomatitis Prevention With a Steroid-based Mouthwash in Post-menopausal Women With Estrogen-receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)- Metastatic or Locally Advanced Breast Cancer

Dose-dependent Anti-inflammatory Effects of Vitamin D in a Human Gingivitis Model

KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)

Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Dentinal Hypersensitivity

Prevention of Broncho-aspiration (BA) in Adult Subjects During Their ICU Stay

A Study to Investigate Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Pain Derived From Exposed Dentine in Response to Chemical, Thermal, Tactile, or Osmotic Stimuli.

A Clinical Study to Evaluate Effects of an Oral Rinse on Plaque and Gingivitis

Potential of an Experimental Mouthwash Formulation to Reduce Dry Mouth Symptoms

Effect of Over-the-counter Toothpastes on Chemotherapy-induced Oral Mucositis

Does Use of Topical Lidocaine in EGD Reduce Amount of IV Midazolam and Fentanyl Required and Shorten Recovery Time

A Two-Week Study of an Anticavity Low pH Mouthwash