- Conditions
- Posttraumatic Stress Disorder
- Interventions
- COGENT (Cognitive ENhancement Training), ST (Sham Training)
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 176 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027 – 2030
- U.S. locations
- 1
- States / cities
- San Diego, California
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Showing 1–24
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- Conditions
- Substance-Related Disorders
- Interventions
- Experimental memory training, Comparator memory training 1, Comparator memory training 2
- Behavioral
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- TBI (Traumatic Brain Injury), PTSD
- Interventions
- V-TRACTS Assessment/Feedback, OPTIONAL Brief Assessment of Thinking, OPTIONAL STEP-Home-Brief, OPTIONAL At-home Exercise Program, OPTIONAL Referral to 12-week STEP-Home, OPTIONAL Clinical Referral
- Behavioral
- Lead sponsor
- VA Boston Healthcare System
- Federal
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2024
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Schizophrenia
- Interventions
- Brain Fitness Program (BFP), Cognitive Package (Cogpack), Commercial Computer Games (Sporcle)
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 25 Years to 65 Years
- Enrollment
- 105 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2018
- U.S. locations
- 2
- States / cities
- Los Angeles, California • West Los Angeles, California
- Conditions
- Mild Cognitive Impairment (MCI), Early Stages of Cognitive Decline, Alzheimer's Disease Dementia, Alzheimer's Disease Diagnosis, Alzheimer's Disease and Related Dementias, Parkinson's Disease, Parkinson's Disease (PD), Parkinson's Disease With Wearing-off Motor Fluctuations, Dementia (Diagnosis), Dementia MCI (Mild Cognitive Impairment)
- Interventions
- Structured wellness care, Wearable brain-computer interface devices, Stem Cell Therapy - Experimental, Control - Placebo Comparator
- Behavioral · Device · Biological + 1 more
- Lead sponsor
- Noah Tech, Corp.
- Industry
- Eligibility
- 55 Years and older
- Enrollment
- 600 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Palisades Park, New Jersey
- Conditions
- Age-related Cognitive Decline
- Interventions
- Computerized Plasticity-Based Adaptive Cognitive Training, Commercially available computerized training
- Other
- Lead sponsor
- Posit Science Corporation
- Industry
- Eligibility
- 65 Years and older
- Enrollment
- 147 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2021
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa • Dallas, Texas
- Conditions
- Traumatic Brain Injury
- Interventions
- memory retraining exercises, placebo control memory exercises
- Behavioral
- Lead sponsor
- Kessler Foundation
- Other
- Eligibility
- 18 Years to 59 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2014
- U.S. locations
- 1
- States / cities
- West Orange, New Jersey
- Conditions
- Aging
- Interventions
- STEM
- Behavioral
- Lead sponsor
- Kessler Foundation
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- East Hanover, New Jersey
- Conditions
- Aging, Mild Cognitive Impairment
- Interventions
- Memory retraining exercises, Placebo control memory exercises
- Behavioral
- Lead sponsor
- Kessler Foundation
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2026
- U.S. locations
- 1
- States / cities
- East Hanover, New Jersey
- Conditions
- ADHD, Weight Loss
- Interventions
- Adaptive Working Memory Training, Non-adaptive cognitive training
- Behavioral
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 37 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Burlington, Vermont
- Conditions
- Alcohol Use Disorder, Post Traumatic Stress Disorder
- Interventions
- Computerized Plasticity-Based Adaptive Cognitive Training
- Other
- Lead sponsor
- Posit Science Corporation
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Traumatic Brain Injury
- Interventions
- Group Memory retraining exercises, Placebo controlled group memory exercise training
- Behavioral
- Lead sponsor
- Kessler Foundation
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- West Orange, New Jersey
- Conditions
- Schizophrenia, Bipolar Disorder, Schizo Affective Disorder
- Interventions
- TDCS, Sham Stimulation, Cognitive Remediation, Bridging Group
- Device · Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Schizophrenia
- Interventions
- Cognitive enhancement therapy (CET), Enriched supportive therapy (EST)
- Behavioral
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 16 Years to 51 Years
- Enrollment
- 67 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2001 – 2016
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Age-related Cognitive Decline
- Interventions
- Computerized Plasticity-Based Adaptive Cognitive Training
- Other
- Lead sponsor
- Posit Science Corporation
- Industry
- Eligibility
- 70 Years and older
- Enrollment
- 135 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2026
- U.S. locations
- 2
- States / cities
- Iowa City, Iowa • Dallas, Texas
- Conditions
- MTBI - Mild Traumatic Brain Injury
- Interventions
- PATH + DigitMemory (DM) neurotraining
- Behavioral
- Lead sponsor
- Perception Dynamics Institute
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2029
- U.S. locations
- 2
- States / cities
- San Diego, California • Solana Beach, California
- Conditions
- Cognitive Impairment, Schizophrenia
- Interventions
- Cognitive Rehabilitation Therapy (CRT) + Skill Training (SDG), Individual Computer Based Cognitive Rehabilitation (ICBCR) and Skills Training (SDG), Skills Group (SDG)
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 59 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2009
- U.S. locations
- 1
- States / cities
- West Haven, Connecticut
- Conditions
- Aggression Childhood, Teen Dating Violence
- Interventions
- Experimental: Intervention (SPARE) plus Treatment as Usual, Treatment as Usual (TAU)
- Behavioral
- Lead sponsor
- Rhode Island Hospital
- Other
- Eligibility
- 11 Years to 13 Years
- Enrollment
- 88 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Motivation, Memory, Self-regulation
- Interventions
- Ventral tegmental area of dopaminergic midbrain (VTA) fMRI neurofeedback
- Behavioral
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 190 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Amnestic Mild Cognitive Impairment
- Interventions
- mSIM intervention plus activity monitoring, Activity monitoring
- Behavioral
- Lead sponsor
- Jennifer Bramen
- Other
- Eligibility
- 50 Years to 80 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Santa Monica, California
- Conditions
- Spinal Cord Injury, Blood Pressure, Cerebral Blood Flow, Cognitive Function
- Interventions
- SPT, SPT Control, mSMT, mSMT Control
- Other
- Lead sponsor
- James J. Peters Veterans Affairs Medical Center
- Federal
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- West Orange, New Jersey
- Conditions
- Mild Cognitive Impairment
- Interventions
- Memory Retraining Exercises, Placebo Control Memory Exercises
- Behavioral
- Lead sponsor
- Kessler Foundation
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 2
- States / cities
- Ann Arbor, Michigan • West Orange, New Jersey
- Conditions
- Spinal Cord Injuries
- Interventions
- Behavorial; memory exercise, Placebo; memory exercise, Behavioral: speed exercises, Placebo speed training
- Behavioral
- Lead sponsor
- Kessler Foundation
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 104 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- West Orange, New Jersey
- Conditions
- Math Learning Disability, Child Development, Developmental Disability, Learning Disabilities, Learning Disabled, Learning Curve, Mathematics Disorder, Dyscalculia, Dyscalculia, Primary, Dyscalculia, Acquired, Specific Learning Disorder, With Impairment in Mathematics, Individuality, Behavior, Child, Behavior and Behavior Mechanisms, Behavior, Decision Making, Neuronal Plasticity, Cognition, Cognition Disorder, Cognitive Dysfunction, Cognitive Change, Cognitive Impairment, Mild, Cognitive Developmental Delay, Cognitive Orientation, Cognitive Delay, Mild, Cognitive Deficits, Mild, Cognitive Abnormality, Neuroscience
- Interventions
- Interventions in Mathematics and Cognitive Skills - Experimental, Interventions in Mathematics and Cognitive Skills - Active Comparator
- Other
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 6 Years to 12 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Palo Alto, California