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ClinicalTrials.gov public records Last synced Oct 26, 2026, 5:47 PM EDT

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Showing 25–48 of 576 matching trials from the live ClinicalTrials.gov search.
Conditions
Cystic Fibrosis
Interventions
Trimethoprim Sulfamethoxazole (TMP/SMX), Minocycline, Mupirocin, Chlorhexidine Gluconate, Environmental Decontamination
Drug · Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
2 Years to 45 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
9
States / cities
Denver, Colorado • Indianapolis, Indiana • Ann Arbor, Michigan + 6 more
Conditions
Acute Respiratory Distress Syndrome
Interventions
Recruitment Maneuver with PEEP and Tidal Volume Optimization
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Glycogen Storage Disease Type II
Interventions
RMT therapy using modified RMT device, Sham-RMT therapy using modified RMT device
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Terminated Phase 1Phase 2 Interventional Results available

Project 4A: Inspiratory Muscle Training and Diaphragm Strength

NCT02367170
Conditions
Sepsis
Interventions
Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure, Midazolam, Volitional Measurement of Maximal Inspiratory Pressure (MIP), Inspiratory Muscle Strength Training (IMST), SHAM Inspiratory Muscle Strength Training (IMST), Diaphragm thickness measurement, Blood and Urine samples
Procedure · Drug · Device + 1 more
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Gainesville, Florida
Completed Not applicable Interventional Results available

Atrial Fibrillation Recurrence in Sleep Apnea

NCT00263757
Conditions
Sleep Apnea, Atrial Fibrillation
Interventions
Adaptive Servo-Ventilation, Usual Care
Device · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Addiction, Addiction Disorders
Interventions
SKY Breathing Program
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Sanborn, New York
Conditions
Intrahepatic Cholangiocarcinoma, Cholangiocarcinoma, Intrahepatic
Interventions
Liver Transplant
Procedure
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
2
States / cities
Newark, New Jersey
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pivot Breath Sensor Performance Study

NCT03870022
Conditions
Smoking Cessation, Smoking, Tobacco
Interventions
Pivot Breath Sensor System, Similar Carbon Monoxide breath sensor system
Device
Lead sponsor
Jennifer Marler, MD
Industry
Eligibility
18 Years to 80 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Redwood City, California
Completed Not applicable Interventional Results available

ALS and Airway Clearance (ALSAC) Therapy

NCT04947436
Conditions
Amyotrophic Lateral Sclerosis, Respiratory Muscle Weakness
Interventions
High Frequency Chest Wall Oscillation, Mechanical insufflation/exsufflation
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
San Antonio, Texas
Not listed Not applicable Interventional Accepts healthy volunteers

Detection of Propofol in Exhaled Breath

NCT02214394
Conditions
Healthy
Interventions
High-performance liquid chromatography Analysis, SMART Device
Other · Device
Lead sponsor
Xhale Assurance
Industry
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2014
U.S. locations
1
States / cities
Gainesville, Florida
Recruiting Not applicable Interventional Accepts healthy volunteers

Sympathetic Overactivity in Post-traumatic Stress Disorder

NCT01627301
Conditions
Post-traumatic Stress Disorder, Prehypertension
Interventions
Device-Guided Breathing (DGB), Sham DGB, Transcutaneous Vagal Nerve Stimulation (tVNS), Sham tVNS
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2027
U.S. locations
1
States / cities
Decatur, Georgia
Conditions
C. Difficile
Interventions
Frozen Microbiota, Lyophilized Microbiota
Biological
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Houston, Texas
Terminated Not applicable Interventional Results available

OPEP Devices in Acute Inpatient Treatment of Pneumonia

NCT04540510
Conditions
Community-acquired Pneumonia
Interventions
OPEP therapy, Standard care
Device · Other
Lead sponsor
Danbury Hospital
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Norwalk, Connecticut
Conditions
HIV, AIDS, Nicotine Dependence
Interventions
Bupropion, Brief Counseling, High-magnitude prize contingency management, Monitored support to quit smoking, No additional treatment, Prize contingency management for abstinence, Low intensity prize contingency management
Drug · Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 80 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Asthma
Interventions
NIOX MINO®
Device
Lead sponsor
Aerocrine AB
Industry
Eligibility
7 Years to 65 Years
Enrollment
235 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
13
States / cities
Byron, Minnesota • Chatfield, Minnesota • Pine Island, Minnesota + 7 more
Conditions
COVID-19
Interventions
Tonation Breathing Techniques, Music Driven Vocal Exercises, Silent Breathing
Behavioral
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Cigarette Smoking
Interventions
Contingency Management, Brief smoking cessation counseling
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Respiratory Distress Syndrome, Adult, Ventilator-Induced Lung Injury, Neurocognitive Dysfunction, Quality of Life, Respiration Disorders
Interventions
Ventilation Inhomogeneity, Diaphragm Ultrasound, Respiratory Inductance Plethysmography, Spirometry, Functional Residual Capacity, MIP/MEP, 6 minute walk test, Neurocognitive Testing, Emotional Health Assessment, Health Related Quality of Life, Functional Status, Respiratory Status Questionnaire
Diagnostic Test
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
1 Month to 18 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Asthma
Interventions
fenoTRACK Device
Device
Lead sponsor
Biometry Inc
Industry
Eligibility
5 Years to 100 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
13
States / cities
Stockton, California • Panama City, Florida • Columbus, Georgia + 10 more
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Asthma and Mindfulness-Based Stress Reduction (MBSR)

NCT00682669
Conditions
Asthma
Interventions
MBSR, HLC
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
21 Years and older
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Worcester, Massachusetts
Conditions
Respiratory Distress Syndrome
Interventions
spontaneous breathing trial
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
48 Hours to 14 Weeks
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Phialdelphia, Pennsylvania • Philadelphia, Pennsylvania
Conditions
Cardiovascular Diseases
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
15 Years and older
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Spinal Cord Injuries
Interventions
High tidal volume, Low tidal volume
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Englewood, Colorado • Houston, Texas
Conditions
Obstructive Sleep Apnea
Interventions
BONGO NASAL EPAP
Device
Lead sponsor
InnoMed Healthscience Inc.
Industry
Eligibility
21 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Antonio, Texas