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ClinicalTrials.gov public records Last synced Oct 18, 2026, 2:43 AM EDT

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Showing 169–192 of 1,208 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Exposed group Clear all
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Pre-Exposure Prophylaxis (PrEP)- Gender Affirming Hormone Therapy (GAHT) Interactions in TGW

NCT04760691
View directory record Official record
Conditions
HIV, Prophylaxis, Transgender
Interventions
Truvada alone, Truvada plus Leuprolide 11.25mg intramuscular injection, Truvada plus Estradiol 1 mg, Truvada plus Estradiol 6 mg, Estradiol 6 mg alone
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Male only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 18, 2026, 2:43 AM EDT
Recruiting No phase listed Observational

Study to Compare Maternal, Fetal, and Infant Outcomes of Women With Mild to Moderate Atopic Dermatitis Exposed to Ruxolitinib Cream During Pregnancy With an Unexposed Control Population

NCT06259669
View directory record Official record
Conditions
Pregnancy Related, Atopic Dermatitis
Interventions
Ruxolitinib Cream
Drug
Lead sponsor
Incyte Corporation
Industry
Eligibility
15 Years to 50 Years · Female only
Enrollment
958 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2033
U.S. locations
1
States / cities
Morrisville, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Oct 18, 2026, 2:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparing a Team-Based Approach to Standard Well-Child Visits To Improve Preventive Care Services

NCT05852392
View directory record Official record
Conditions
Pediatric, Well Child Care
Interventions
Adapted PARENT Model
Other
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
9 Months to 15 Months
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
3
States / cities
Honolulu, Hawaii • Columbus, Ohio • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 18, 2026, 2:43 AM EDT
Recruiting No phase listed Observational

Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation

NCT04668872
View directory record Official record
Conditions
Colon Cancer Liver Metastasis, Colon Cancer, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum, Liver Metastasis Colon Cancer, Colorectal Cancer
Interventions
Y90 TARE, PET/CT, PET/MRI
Radiation · Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 18, 2026, 2:43 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

First-in-Human PfSPZ-LARC2 Vaccination/CHMI

NCT06735209
View directory record Official record
Conditions
Malaria
Interventions
PfSPZ Vaccine, PfSPZ (7G8) Challenge, Sodium Chloride, 0.9%
Biological · Other
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 45 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 18, 2026, 2:43 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Trial to Evaluate CIS43LS in Healthy Adults

NCT04206332
View directory record Official record
Conditions
Malaria
Interventions
VRC-MALMAB0100-00-AB, Plasmodium falciparum (P. falciparum) sporozoite challenge
Drug · Other
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 50 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
Baltimore, Maryland • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 18, 2026, 2:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

E-cigarette Switching Older Adults

NCT06534905
View directory record Official record
Conditions
Tobacco Use, Opioid Use Disorder, Tobacco-Related Disorders
Interventions
E-cigarette, Control/Standard Advice
Other · Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
50 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 18, 2026, 2:43 AM EDT
Recruiting Phase 4 Interventional

Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children

NCT04783857
View directory record Official record
Conditions
Smoking, Smoking Cessation, Smoking Reduction
Interventions
Progesterone 200 MG Oral Capsule
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 18, 2026, 2:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Personalized Approach To Habits - Sleep

NCT07029919
View directory record Official record
Conditions
Adolescent Behavior, Sleep Disturbance, Asthma in Children, Knowledge, Attitudes, Practice, Attitude, Habits
Interventions
PATH-S app
Behavioral
Lead sponsor
KDH Research & Communication
Industry
Eligibility
14 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 18, 2026, 2:43 AM EDT
Active, not recruiting Not applicable Interventional

Creating a Healthy L.I.F.E: Lifestyle Interventions For Epilepsy

NCT05283200
View directory record Official record
Conditions
Lifestyle
Interventions
Yoga, Cognitive Behavioral Therapy, Music
Behavioral
Lead sponsor
Imad Najm MD
Other
Eligibility
18 Years to 75 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 18, 2026, 2:43 AM EDT
Recruiting No phase listed Observational

Application of a Clinical Decision Support System to Reduce Mechanical Ventilation Duration After Cardiac Surgery in Children

NCT05687292
View directory record Official record
Conditions
Congenital Heart Disease
Interventions
Clinical decision support system (CDSS) for ventilator weaning
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Day to 12 Years
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 18, 2026, 2:43 AM EDT
Completed No phase listed Observational

A Study of Severe Uterine Bleeding Following Exposure to Direct Oral Anticoagulants

NCT04394234
View directory record Official record
Conditions
Uterine Hemorrhage
Interventions
Direct oral anticoagulant (DOACs), Warfarin
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
961,985 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Titusville, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 18, 2026, 2:43 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Metformin in a Non-Diabetic Patient Population

NCT03772964
View directory record Official record
Conditions
Inflammatory Response
Interventions
MetFORMIN Hydrochloride ER, Placebo
Drug
Lead sponsor
Brian Zuckerbraun
Other
Eligibility
55 Years to 85 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 11, 2023 · Synced Oct 18, 2026, 2:43 AM EDT
Recruiting Phase 2Phase 3 Interventional

Divided or Single Exposure (DOSE) Study

NCT05459402
View directory record Official record
Conditions
Opioid Use Disorder, Chronic Pain, Methadone
Interventions
Methadone (100% dose), Methadone (50% dose)
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 18, 2026, 2:43 AM EDT
Completed No phase listed Observational

Replication of the ISAR-REACT 5 Antiplatelet Trial in Healthcare Claims Data

NCT05086081
View directory record Official record
Conditions
Acute Coronary Syndrome
Interventions
Ticagrelor 90mg, Prasugrel 10mg
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 120 Years
Enrollment
28,389 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 18, 2026, 2:43 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

HIV Pre-Exposure Prophylaxis Among an Unrecognized Sexual Minority Population

NCT05815030
View directory record Official record
Conditions
Pre-Exposure Prophylaxis
Interventions
video informational/educational intervention
Other
Lead sponsor
The Alternative Sexualities Health Research Alliance
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rio Vista, California
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Oct 18, 2026, 2:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing a Novel Phototherapy Kiosk to Oral Vitamin D Supplementation

NCT04556136
View directory record Official record
Conditions
Hypovitaminosis D
Interventions
Standing Phototherapy Kiosk, D3 Oral supplement
Device · Dietary Supplement
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years to 69 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Mar 13, 2024 · Synced Oct 18, 2026, 2:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Development of a Therapeutic Device to Improve Speech Sound Differentiation in Preterm Infants

NCT06063122
View directory record Official record
Conditions
Premature Birth
Interventions
smallTalk NICU Active
Device
Lead sponsor
Thrive Neuromedical, LLC
Industry
Eligibility
32 Weeks to 35 Weeks
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Atlanta, Georgia • Chagrin Falls, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 18, 2026, 2:43 AM EDT
Completed No phase listed Observational

Fluoroquinolone Associated Disability

NCT03535558
View directory record Official record
Conditions
Bronchitis, Sinusitis, Urinary Tract Infections
Interventions
Fluoroquinolone (FQ), Azithromycin (AZ), Sulfamethoxazole/Trimethoprim (ST) Fixed Dose Combination
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
239,306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Titusville, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 29, 2019 · Synced Oct 18, 2026, 2:43 AM EDT
Completed Not applicable Interventional

Pain Management Following Musculoskeletal Injury

NCT01689675
View directory record Official record
Conditions
Musculoskeletal Strain, Musculoskeletal Sprain, Injury of Musculoskeletal System
Interventions
Computer based pain management
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Baltimore, Maryland • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 18, 2026, 2:43 AM EDT
Recruiting No phase listed Observational

Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

NCT02103361
View directory record Official record
Conditions
Psoriasis, Pregnancy, Psoriatic Arthritis, Crohn Disease
Interventions
Ustekinumab, Guselkumab
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2031
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Oct 18, 2026, 2:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Beaumont Health Large-scale Automated Serologic Testing for COVID-19

NCT04349202
View directory record Official record
Conditions
COVID-19, Coronavirus Infection, Severe Acute Respiratory Syndrome Coronavirus 2
Interventions
EUROIMMUN assay
Diagnostic Test
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
20,614 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 18, 2026, 2:43 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Adaptation of Mindfulness Training to Treat Moral Injury in Veterans

NCT05341882
View directory record Official record
Conditions
Mindfulness, Educational Support
Interventions
Mindfulness, Educational Support
Behavioral
Lead sponsor
Old Dominion University
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 5, 2023 · Synced Oct 18, 2026, 2:43 AM EDT
Completed Phase 2 Interventional Results available

Nivolumab for Recurrent or Progressive IDH Mutant Gliomas

NCT03557359
View directory record Official record
Conditions
Gliomas
Interventions
Nivolumab
Drug
Lead sponsor
Fabio Iwamoto, MD
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
4
States / cities
Miami, Florida • Boston, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 18, 2026, 2:43 AM EDT