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Showing 25–48 of 4,643 matching trials from the live ClinicalTrials.gov search.
Completed Phase 2Phase 3 Interventional Results available

Topiramate and Prolonged Exposure

NCT03176953
Conditions
PTSD and Alcohol Use Disorder
Interventions
topiramate, prolonged exposure, placebo
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
San Diego, California
Conditions
Coronary Artery Disease
Interventions
Riociguat (BAY63-2521)
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Multiple Sclerosis (Relapsing Remitting)
Interventions
Perturbation Training, Treadmill Walking
Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
45 Years to 89 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Completed Not applicable Interventional Accepts healthy volunteers

Particulate Matter, Blood Pressure, and the Sympathetic Nervous System

NCT03079843
Conditions
Air Pollution
Interventions
exposure to particulate matter with N 95 facemask, exposure to particulate matter with no face mask
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Diabetes Mellitus, Hypoglycemia
Interventions
Patient Group (Hypoglycemia Prevention Program), Primary Care Physician Group, Clinic Staff Group
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

mLab App Plus: A Randomized Controlled Trial of a Mobile Health (mHealth) Intervention

NCT06059443
Conditions
HIV Infections, Sexually Transmitted Diseases, Viral, Syphilis
Interventions
mLab App Plus
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 39 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
New York, New York • Nashville, Tennessee
Conditions
Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Separation Anxiety Disorder, Specific Phobia, Obsessive Compulsive Disorder (OCD), Panic Disorder (With or Without Agoraphobia)
Interventions
Relaxation and Mentorship Training (RMT), Stepped Care Targeting Exposure and Parenting for Anxiety (STEP-A)
Behavioral
Lead sponsor
Andrew Wiese
Other
Eligibility
7 Years to 17 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Completed No phase listed Observational

Emulation of the PALOMA-2 Trial

NCT07178743
Conditions
Advanced Breast Cancer
Interventions
Initiation of palbociclib plus letrozole, Initiation of letrozole
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
6,097 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Constipation, Pregnancy
Interventions
No Intervention
Other
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 44 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Health Care Quality, Access, and Evaluation, Smoking Cessation
Interventions
training in smoking cessation
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
1,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Rochester, New York
Conditions
Advanced Solid Tumors
Interventions
Gemcitabine, Docetaxel, Temozolomide, Cisplatin, Erlotinib, LY573636
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
19
States / cities
Birmingham, Alabama • Fayetteville, Arkansas • Denver, Colorado + 16 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Experimental Approach to Test Predictions of Body Weight Regulation Models

NCT06309576
Conditions
Obesity, Underweight
Interventions
Fasting-refeeding cycle
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Adaptation and Evaluation of RESTORE

NCT07104474
Conditions
Nurse, Burnout, Healthcare Workers
Interventions
RESTORE
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
470 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Madison, Wisconsin
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

A Multilevel Intervention to Prevent Noise Exposure in Farmworkers

NCT07554378
Conditions
Noise Exposure, Hearing Loss, Noise-Induced, Occupational Exposure
Interventions
Multilevel Hearing Protection Training
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
San Diego, California
Conditions
Hypertension
Interventions
BP measurement & pharmacy, BP educational materials
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
35 Years to 79 Years · Male only
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers

Linkage of Transgender Individuals to PrEP

NCT03191474
Conditions
HIV Seronegativity, Linkage
Interventions
T-POWr Intervention
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Los Angeles, California • San Diego, California
Conditions
Hypertension
Interventions
Propranolol or Carvedilol, Atenolol, Bisoprolol or Sotalol
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
65 Years and older
Enrollment
817,337 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Renal Cell Carcinoma
Interventions
Axitinib
Drug
Lead sponsor
PrECOG, LLC.
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
3
States / cities
Omaha, Nebraska • Cleveland, Ohio • Philadelphia, Pennsylvania
Not listed Phase 1 Interventional Accepts healthy volunteers

Hyperbaric Oxygen, Neutrophil-oxidative Burst, and Cytokines

NCT02563678
Conditions
Infection
Interventions
Hyperbaric Oxygen, Hyperbaric Air/Oxygen, Normobaric oxygen
Drug · Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
2
States / cities
Murray, Utah • Salt Lake City, Utah
Conditions
Generalized Anxiety Disorder
Interventions
Exposure-based therapy, Behavioral Activation therapy, Computer-based behavioral assessment, Surveys and Interviews, Magnetic resonance imaging (MRI), Electroencephalography (EEG)
Behavioral · Device
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Tulsa, Oklahoma
Completed Not applicable Interventional Results available

Babies Living Safe and Smokefree

NCT02602288
Conditions
Second Hand Tobacco Smoke, Nicotine Dependence
Interventions
Ask, Advise, Refer, Telebased tobacco counseling, Telebased nutrition counseling, Mobile phone smoking cessation application, Mobile phone nutrition application, Nicotine polacrilex
Behavioral · Device · Drug
Lead sponsor
Temple University
Other
Eligibility
18 Years and older · Female only
Enrollment
396 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Conditions
Risk for an Alcohol-Exposed Pregnancy, Hazardous Alcohol Use, Risk for Unintended Pregnancy
Interventions
Brief Motivational Counseling
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years to 44 Years · Female only
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
11
States / cities
Fort Lauderdale, Florida • Dayton, Texas • Houston, Texas + 1 more
Conditions
COVID-19, SARS-CoV-2
Interventions
AZD5156 (Parent study Sentinel Safety Cohort), Placebo (Parent study Sentinel Safety Cohort), EVUSHELD™ (Parent study Main Cohort), AZD3152 (Parent study Main Cohort), Placebo (Parent study Main Cohort), AZD3152 (Sub-study), AZD7442 - EVUSHELD™ (Sub-study), AZD7442 (EVUSHELD™) (Sub-study) Immunocompromised participants offered AZD3152
Biological
Lead sponsor
AstraZeneca
Industry
Eligibility
12 Years to 130 Years
Enrollment
3,882 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
130
States / cities
Birmingham, Alabama • Mobile, Alabama • Glendale, Arizona + 108 more
Conditions
Insomnia
Interventions
CBTI-CS, Sleep Hygiene, CBTI-CS via Telehealth
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts