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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:20 PM EDT

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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Extended Vision IOL Clear all
Completed Phase 4 Interventional Results available

Symfony vs Vivity in Dim Light

NCT06229106
View directory record Official record
Conditions
Cataract
Interventions
Symfony IOL, Vivity IOL
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
50 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Sarasota, Florida • Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 14, 2025 · Synced Oct 21, 2026, 2:20 PM EDT
Completed Not applicable Interventional

Clinical Evaluation and Comparison of the Tecnis Symfony Optiblue and Tecnis Symfony IOLs

NCT06567834
View directory record Official record
Conditions
Cataract, Presbyopia
Interventions
Tecnis Symfony Optiblue/Tecnis Symfony Optiblue Toric (Models ZXR00V/ZXW150), Tecnis Symfony/Tecnis Symfony Toric (Models ZXR00/ZXT150)
Device
Lead sponsor
Empire Eye and Laser Center
Other
Eligibility
22 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Bakersfield, California
Source: ClinicalTrials.gov public record
Updated Aug 23, 2024 · Synced Oct 21, 2026, 2:20 PM EDT
Completed Not applicable Interventional

Clinical Outcomes Following Implantation of Tecnis Synergy and Symfony Intraocular Lens

NCT05541796
View directory record Official record
Conditions
Cataract
Interventions
Intraocular lens
Device
Lead sponsor
George O. Waring IV
Other
Eligibility
40 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Oct 21, 2026, 2:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Rotational Stability of Acrysof IQ Vivity Extended Vision Toric IOL and Refractive Visual Outcome.

NCT05119127
View directory record Official record
Conditions
Cataract
Interventions
Alcon Vivity toric intra ocular lens
Device
Lead sponsor
Kevin Barber
Other
Eligibility
45 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
DeLand, Florida
Source: ClinicalTrials.gov public record
Updated Nov 12, 2021 · Synced Oct 21, 2026, 2:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Vision After Vivity IOL Implantation With a Target of Slight Myopia in the Non-dominant Eye

NCT04482439
View directory record Official record
Conditions
Cataract
Interventions
Vivity Extended Depth of Focus intraocular lens (IOL)
Device
Lead sponsor
Newsom Eye & Laser Center
Other
Eligibility
40 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sebring, Florida
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Oct 21, 2026, 2:20 PM EDT
Completed No phase listed Observational

Vivity Outcomes in Patients With Early Stage Glaucoma

NCT04670575
View directory record Official record
Conditions
Glaucoma, Cataract, Presbyopia
Interventions
Cataract Surgery with Implantation of Vivity Extended Range of Vision IOL
Procedure
Lead sponsor
Vance Thompson Vision
Other
Eligibility
45 Years and older
Enrollment
27 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Oct 21, 2026, 2:20 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Long Term Outcomes of Vivity Intra Ocular Lens(IOL) Versus Control

NCT04561570
View directory record Official record
Conditions
Cataract
Interventions
Vivity ACRYSOF IQ IOL Group, ACRYSOF IQ IOL Control Group
Device
Lead sponsor
John Berdahl, MD
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 21, 2026, 2:20 PM EDT
Completed Not applicable Interventional Results available

A Clinical Study of the ACRYSOF® IQ Extended Depth of Focus Intraocular Lens (IOL)

NCT03274986
View directory record Official record
Conditions
Cataract
Interventions
ACRYSOF® IQ Extended Depth of Focus IOL, ACRYSOF® IQ Monofocal IOL, Cataract surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
11
States / cities
Birmingham, Alabama • Fort Collins, Colorado • Bradenton, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 21, 2026, 2:20 PM EDT
Completed Not applicable Interventional Results available

Single-center, Double-arm, Prospective Clinical Trial to Compare Visual Performance of Non-diffractive Extended Vision and Neutral Aspheric Monofocal Intraocular Lenses

NCT04591054
View directory record Official record
Conditions
Cataract, Presbyopia
Interventions
Extended Vision IOL, Neutral Aspheric Monofocal IOL
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 95 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 21, 2026, 2:20 PM EDT
Completed Not applicable Interventional

Post Market Clinical Follow-up (PMCF) Study of Clareon Vivity & Clareon PanOptix

NCT05796453
View directory record Official record
Conditions
Aphakia, Astigmatism, Presbyopia
Interventions
Clareon Vivity IOL - Non Toric, Clareon Vivity IOL - Toric, Clareon PanOptix Trifocal IOL - Non Toric, Clareon PanOptix Trifocal IOL - Toric
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
6
States / cities
Torrance, California • Jacksonville, Florida • Liverpool, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 21, 2026, 2:20 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Impact of a Novel Extended Depth of Focus Intraocular Lens on Visual and Lifestyle Enhancement

NCT04570579
View directory record Official record
Conditions
Cataract, Cataract Senile, Presbyopia
Interventions
Vivity Extended Depth of Focus Intraocular Lens
Device
Lead sponsor
Alanna Nattis, DO
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Babylon, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Oct 21, 2026, 2:20 PM EDT
Completed Not applicable Interventional Results available

Tecnis ZLB00 & Symfony Intraocular Lens Combination Outcomes

NCT03771274
View directory record Official record
Conditions
Cataract Bilateral, Presbyopia
Interventions
Tecnis ZLB00 & Symfony IOL
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
40 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2020 · Synced Oct 21, 2026, 2:20 PM EDT
Not yet recruiting Phase 4 Interventional

Clinical Evaluation of Visual Performance, Spectacle Independence, and Patient Satisfaction With TECNIS PureSee Mini-Monovision and TECNIS PureSee-TECNIS Odyssey Mix-Match

NCT07860567
View directory record Official record
Conditions
Presbyopia Correction, Presbyopia, Dysphotopsia, Visual Acuity
Interventions
TECNIS PureSee IOL (Model DEN00V/DET150), TECNIS Odyssey IOL (Model DRN00V/DRT150)
Device
Lead sponsor
Dr. Daniel H. Chang, MD
Other
Eligibility
22 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Bakersfield, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 21, 2026, 2:20 PM EDT
Withdrawn Not applicable Interventional

Evaluation of AcrySof IQ Vivity Extended Vision Intraocular Lenses

NCT06541795
View directory record Official record
Conditions
Aphakia, Presbyopia, Residual Refractive Cylinder
Interventions
AcrySof IQ Vivity Extended Vision IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Oct 21, 2026, 2:20 PM EDT
Completed Not applicable Interventional Results available

Clinical Investigation of a New Intraocular Lens

NCT02203721
View directory record Official record
Conditions
Cataract
Interventions
TECNIS Symfony Extended Range of Vision IOL, Model ZXR00, TECNIS Monofocal IOL, Model ZCB00
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
22 Years to 99 Years
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
15
States / cities
Rogers, Arkansas • Bakersfield, California • Boynton Beach, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Oct 21, 2026, 2:20 PM EDT
Completed Not applicable Interventional Results available

Symfony Toric Intraocular Lens Visual Outcomes

NCT03082599
View directory record Official record
Conditions
Cataract Bilateral, Astigmatism Bilateral
Interventions
Presbyopia and astigmatism correcting intraocular lens
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
40 Years to 99 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
Stillwater, Minnesota • Garden City, New York • Mt. Pleasant, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 21, 2026, 2:20 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Visual Outcomes After Vivity Toric IOL Implantation

NCT04675489
View directory record Official record
Conditions
Refractive Assessment
Interventions
Procedure: Vivity Toric IOL
Other
Lead sponsor
EVP Eye Care
Other
Eligibility
45 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Grand Junction, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Oct 21, 2026, 2:20 PM EDT
Completed Not applicable Interventional Results available

Visual Performance With Clareon® Vivity® Intraocular Lenses (IOLs)

NCT06784063
View directory record Official record
Conditions
Astigmatism
Interventions
Clareon Vivity Extended Vision IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
3
States / cities
Bloomfield Hills, Michigan • Dallas, Texas • Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 21, 2026, 2:20 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Clareon Vivity/Vivity Toric

NCT05852470
View directory record Official record
Conditions
Aphakia
Interventions
Clareon Vivity/Vivity Toric Extended Vision IOL, Clareon Monofocal/Clareon Toric IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
7
States / cities
Torrance, California • Fort Collins, Colorado • Bloomfield Hills, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 21, 2026, 2:20 PM EDT
Completed Phase 1 Interventional

A Safety Study of Rituximab Plus MTX Injected Into the Cerebrospinal Fluid in the Treatment of Brain Lymphoma

NCT00221325
View directory record Official record
Conditions
Central Nervous System Lymphoma, Intraocular Lymphoma
Interventions
Intraventricular Rituximab Plus MTX
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
4
States / cities
San Francisco, California • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2015 · Synced Oct 21, 2026, 2:20 PM EDT