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ClinicalTrials.gov public records Last synced Nov 10, 2026, 7:47 PM EST

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Showing 1–24 of 33 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Extra Virgin Olive Oil Clear all

Conditions: Heart Failure With Reduced Ejection Fraction (HFrEF)
Interventions: Extra-virgin olive oil; Other
Lead sponsor: Old Dominion University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Norfolk, Virginia

Conditions: Alzheimer Disease
Interventions: Extra virgin olive oil; Dietary Supplement
Lead sponsor: Augusta University; Other
Eligibility: 30 Years to 55 Years
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Multiple Sclerosis, Cognitive Change, Nutrition, Healthy
Interventions: MIND Diet, Control Diet; Other
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 18 Years to 64 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Urbana, Illinois

Conditions: Type 2 Diabetes
Interventions: Extra Virgin Olive Oil, Refined Olive Oil; Other
Lead sponsor: Griffin Hospital; Other
Eligibility: 25 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Derby, Connecticut

Conditions: Hypertension (HTN), Obesity &Amp; Overweight, Sedentary
Interventions: MIND HIIT; Other
Lead sponsor: Texas Woman's University; Other
Eligibility: 18 Years to 74 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Platelet Aggregation, Nutritional and Metabolic Disease, Cardiovascular Diseases
Interventions: Oleocanthal-Rich Extra Virgin Olive Oil, Oleocanthal-low Extra Virgin Olive Oil; Other
Lead sponsor: University of California, Davis; Other
Eligibility: 20 Years to 45 Years · Male only
Enrollment: 26 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Davis, California

Conditions: Overactive Bladder
Interventions: Omega 3 Fatty Acid, Placebo; Drug
Lead sponsor: TriHealth Inc.; Other
Eligibility: 18 Years to 85 Years · Female only
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Cardiovascular Diseases
Interventions: Low polyphenol concentration extra virgin olive oil (EVOO), High polyphenol concentration extra virgin olive oil (EVOO); Dietary Supplement
Lead sponsor: Ralph Hamill; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 3
States / cities: Brunswick, Maine • Rockport, Maine • Scarborough, Maine

Conditions: Alzheimer Disease, Cerebral Amyloid Angiopathy
Interventions: EVOO, OO; Other
Lead sponsor: Auburn University; Other
Eligibility: 55 Years to 75 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Auburn, Alabama

Conditions: Coronary Artery Disease
Interventions: FMD Arm; Dietary Supplement
Lead sponsor: Hypertension Institute, Nashville; Other
Eligibility: 35 Years to 75 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Gestational Weight Gain, Diet, Healthy
Interventions: MedDiet Program, ACOG-based Dietary Program; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older · Female only
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Obesity, Hypercholesterolemia, Cardiovascular Disease
Interventions: Plant-Based Diet, American Heart Association Diet, Mediterranean Diet; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 9 Years to 18 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Hypertension, Vascular Stiffness
Interventions: Extra Virgin Olive Oil, Control Oil; Dietary Supplement
Lead sponsor: University of Vermont Medical Center; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Mild Cognitive Impairment, Insulin Resistance
Interventions: Low-Carbohydrate Diet, Low-Fat Diet; Other
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 50 Years to 85 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Cognitive Change, Diet, Healthy, Metabolic Syndrome, Protection Against
Interventions: MIND Diet, Control Diet; Other
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 45 Years to 64 Years
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Urbana, Illinois

Conditions: Healthy
Interventions: essential oil supplement, Essential Oil, Placebo supplement, placebo essential oil; Dietary Supplement · Other
Lead sponsor: dōTERRA International; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Pleasant Grove, Utah

Conditions: Healthy, Dietary Supplement
Interventions: Ozone, Fish Oil, Olive Oil; Drug · Dietary Supplement
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 35 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Obesity, Heart Failure With Normal Ejection Fraction
Interventions: UFA dietary recommendations; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Dry Eye Disease, Meibomian Gland Dysfunction
Interventions: Sunflower lecithin, Olive oil; Dietary Supplement
Lead sponsor: George Washington University; Other
Eligibility: 18 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Pregnancy Complications
Interventions: Med-South Lifestyle Intervention for Pregnancy--Arm 1, Med-South Lifestyle Intervention for Pregnancy--Arm 2; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Psoriasis
Interventions: Mediterranean Diet; Behavioral
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years to 94 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Atherosclerosis
Interventions: Not listed
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 83 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Heart Failure With Normal Ejection Fraction, Obesity
Interventions: Increasing daily unsaturated fatty acid consumption; Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Cardiovascular Diseases, Cardiovascular Risk Factor, Obesity
Interventions: Mediterranean diet, Olive oil and mixed nuts, American Heart Association; Behavioral · Dietary Supplement
Lead sponsor: Auburn University; Other
Eligibility: 19 Years and older
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: Auburn, Alabama

Search by objective public record fields.

Olive Oil Supplementation for Heart Failure With Reduced Ejection Fraction

Does EVOO Induce Gene and Metabolic Changes in Healthy Subjects

Remote Evaluation of MIND Diet

Post-prandial Effects of Extra Virgin Olive Oil on Endothelial Function in Adults at Risk for Type 2 Diabetes

Mediterranean-DASH Intervention for Neurodegenerative Delay and High-Intensity Interval Training in Adults With Hypertension

Acute Assessment of Platelet Reactivity After the Intake of Oleocanthal

Oxybutynin and Omega-3 for OAB (Overactive Bladder)

A Multicenter Pilot Study to Evaluate the Effect of EVOO on Lipid Parameters

Auburn University Research on Olive Oil for Alzheimer's Disease (AU-ROOAD)

Evaluation of a Fasting Mimicking Diet

Implementation of a Mediterranean Diet Program for Overweight or Obese Pregnant Women in a Low-resource Clinical Setting

Plant-Based, American Heart Assoc. or Mediterranean Diets In 9-18 yo With BMI >95%, Cholesterol >169 and Their Parents

Cardiovascular Effects of EVOO in Healthy Reproductive-aged Women

Effect of a Modified Ketogenic-Mediterranean Diet on Alzheimer's Disease

Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)

Essential Oil-Based Product System for Digestive Support

Efficacy of Fish Oil or Olive Oil Supplementation on the Health Effects of Ozone Exposure in Healthy Young Subjects

Unsaturated Fatty Acids to Improve Cardiorespiratory Fitness in Obesity and HFpEF

Effect of Sunflower Lecithin Supplementation on Meibomian Gland Function in Adults With Dry Eye Disease

Med-South Lifestyle Program for Pregnancy

Mediterranean Diet vs no Dietary Intervention for Improving Signs and Symptoms of Psoriasis in Patients Treated With Anti-IL-17 or Anti-IL-23 Inhibitors

Effects of EGCG-Enhanced Extra Virgin Olive Oil on Endothelial Function

Unsaturated Fatty Acids Enriched-diet to Improve Cardiorespiratory Fitness, Metabolic Flexibility and Glucose Tolerance in Obese Patients

A Mediterranean Diet Nutrition Education Program for the Reduction of Cardiovascular Disease Risk in the Southeastern U.S.