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ClinicalTrials.gov public records Last synced Oct 28, 2026, 2:32 AM EDT

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Showing 73–94 of 94 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Extracellular Matrix Clear all
Not yet recruiting Phase 1 Interventional

Study of Intramyocardial Injection of Ventrix Bio Extracellular Matrix (VentriGel) to Assess the Safety and Feasibility in Pediatric Patients with Hypoplastic Left Heart Syndrome (HLHS)

NCT06461676
View directory record Official record
Conditions
Hypoplastic Left Heart Syndrome
Interventions
Ventrix Bio Extracellular Matrix
Drug
Lead sponsor
Emory University
Other
Eligibility
Up to 1 Year
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 28, 2026, 2:32 AM EDT
Suspended Not applicable Interventional

Porcine Extracellular Matrix Nerve Wrap in Neck Dissection for Head and Neck Cancer

NCT07268092
View directory record Official record
Conditions
Head and Neck Cancer, Neck Dissection, Postoperative Complications
Interventions
Porcine Extracellular Matrix Nerve Wrap (AxoGuard Nerve Protector™)
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 28, 2026, 2:32 AM EDT
Completed No phase listed Observational

Effect of MitraClip on Acute and Chronic Reverse Cardiac Remodeling Assessed by CMR: The MITRA-REVERSE Study

NCT02924363
View directory record Official record
Conditions
Mitral Regurgitation
Interventions
Cardiac MRI with or without contrast dye, Blood sample
Diagnostic Test
Lead sponsor
Dipan Shah
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
2
States / cities
Atlanta, Georgia • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 28, 2026, 2:32 AM EDT
Completed Phase 2 Interventional Results available

A Multicenter, Randomized, Double-blind, Placebo Controlled, Clinical Trial to Evaluate the Safety, Tolerability and Preliminary Effectiveness of 2 Doses of Intradiscal rhGDF-5 (Single Administration) for the Treatment of Early Stage Lumbar Disc Degeneration

NCT01124006
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Intradiscal rhGDF-5, Water for injection
Drug · Other
Lead sponsor
DePuy Spine
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
10
States / cities
Phoenix, Arizona • Santa Monica, California • Durango, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2016 · Synced Oct 28, 2026, 2:32 AM EDT
Withdrawn Phase 2Phase 3 Interventional Accepts healthy volunteers

Vaginal Progesterone in Twins With Short Cervix

NCT01812239
View directory record Official record
Conditions
Premature Birth
Interventions
Vaginal Progesterone gel., fetal fibronectin swab., Placebo gel
Drug · Procedure
Lead sponsor
Obstetrix Medical Group
Industry
Eligibility
18 Years to 60 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2014 · Synced Oct 28, 2026, 2:32 AM EDT
Recruiting Not applicable Interventional

INNOVEN: Efficacy of Porcine Placental Extracellular Matrix Plus Standard of Care (SOC) Versus SOC Alone

NCT06606210
View directory record Official record
Conditions
Wound Heal, Venous Leg Ulcer
Interventions
InnovaMatrix® AC
Device
Lead sponsor
ConvaTec Inc.
Industry
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
North Port, Florida
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 28, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Hydrolyzed Collagen and Vitamin C on Explosive Performance

NCT04437758
View directory record Official record
Conditions
Collagen Synthesis, Rate of Force (RFD) Development
Interventions
Collagen and Vitamin C powder mix nutritional intervention, Maltodextrin placebo powder, Maximum power training exercise
Dietary Supplement · Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 30 Years · Male only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jun 18, 2020 · Synced Oct 28, 2026, 2:32 AM EDT
Completed Not applicable Interventional Results available

Musculotendinous Tissue Repair Unit and Reinforcement (MTURR)

NCT01292876
View directory record Official record
Conditions
Traumatic Injury, Muscle Injury, Tendon Injury, Soft Tissue Injury, Extremity Injury
Interventions
Extracellular Matrix
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
Bethesda, Maryland • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 7, 2020 · Synced Oct 28, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer

NCT04753359
View directory record Official record
Conditions
Colorectal Cancer, Diet Habit
Interventions
Med, WL
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
45 Years to 75 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 28, 2026, 2:32 AM EDT
Terminated Phase 4 Interventional Results available

Use of INTEGRA™ Flowable Wound Matrix to Manage Diabetic Foot Ulcers

NCT01108263
View directory record Official record
Conditions
Diabetes, Foot Ulcer
Interventions
INTEGRA™ Flowable Matrix (Collagen)
Drug
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 17, 2014 · Synced Oct 28, 2026, 2:32 AM EDT
Suspended Not applicable Interventional

Effect of Hyaluronic Acid ECM on Venous Ulcers

NCT02930499
View directory record Official record
Conditions
Venous Ulcers
Interventions
Hyalomatrix extra-cellular matrix, Mepilex wound dressing
Device
Lead sponsor
Calvary Hospital, Bronx, NY
Other
Eligibility
21 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 30, 2017 · Synced Oct 28, 2026, 2:32 AM EDT
Terminated Phase 3 Interventional

Prospective Assessment of the Efficacy of Hyaluronate Knee Injections in Patients With Osteoarthritis

NCT00323778
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Hyalgan
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
45 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2008 · Synced Oct 28, 2026, 2:32 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety Study of Anti-Influenza Virus Monoclonal Antibody to Treat Influenza

NCT01390025
View directory record Official record
Conditions
Influenza, Human
Interventions
TCN-032, Placebo
Biological
Lead sponsor
Theraclone Sciences, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 2, 2012 · Synced Oct 28, 2026, 2:32 AM EDT
Completed Phase 1 Interventional

Endostatin in Treating Patients With Advanced Solid Tumors

NCT00004229
View directory record Official record
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
recombinant human endostatin
Biological
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1999
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2013 · Synced Oct 28, 2026, 2:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Alveolar Ridge Preservation Following Tooth Extraction.

NCT05505084
View directory record Official record
Conditions
Tooth Fractures, Tooth Extraction Status Nos, Caries
Interventions
Tooth extraction and ridge preservation using different barrier mermbranes
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 28, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gelatin, Collagen, Gummy and PINP

NCT03357432
View directory record Official record
Conditions
Collagen Synthesis
Interventions
gelatin, collagen, gummy dose
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Nov 9, 2018 · Synced Oct 28, 2026, 2:32 AM EDT
Not yet recruiting No phase listed Observational

PET/MRI of Primary Sclerosing Cholangitis

NCT06252610
View directory record Official record
Conditions
PSC
Interventions
Radiotracer Injection, Contrast Media, Magnetic Resonance, Imaging
Drug · Diagnostic Test
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 99 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 28, 2026, 2:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Blood Nitrate/Nitrite Concentrations Following Acute Ingestion of Resync in Men and Women

NCT04125940
View directory record Official record
Conditions
Healthy
Interventions
Resync, Resync + Collagen, Placebo
Dietary Supplement · Other
Lead sponsor
University of Memphis
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Oct 28, 2026, 2:32 AM EDT
Recruiting Phase 2 Interventional

Phase 2 Clinical Trial of CartiLife® in the United States

NCT04744402
View directory record Official record
Conditions
Articular Cartilage Defect, Articular Cartilage Degeneration
Interventions
Autologous Chondrocyte Implantation (CartiLife®)
Drug
Lead sponsor
Biosolution Co., Ltd.
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
5
States / cities
Irvine, California • La Mesa, California • Lafayette, Louisiana + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2023 · Synced Oct 28, 2026, 2:32 AM EDT
Recruiting Phase 4 Interventional

Study Comparing Avance Nerve Graft and Autograft for Functional Recovery Following Mixed and Motor Peripheral Nerve Reconstruction

NCT07657182
View directory record Official record
Conditions
Peripheral Nerve Injury, Peripheral Nerve Discontinuity, Mixed Peripheral Nerve Injury, Motor Peripheral Nerve Injury, Upper Extremity Nerve Injury
Interventions
Avance Nerve Graft, Sural nerve autograft
Biological · Procedure
Lead sponsor
Axogen Corporation
Industry
Eligibility
18 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
3
States / cities
Orlando, Florida • Indianapolis, Indiana • Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 28, 2026, 2:32 AM EDT
Completed Not applicable Interventional

A Longitudinal Study to Evaluate an Extracellular Matrix (MatriStem®) for the Treatment of Diabetic Foot Ulcers

NCT02750280
View directory record Official record
Conditions
Neuropathic Diabetic Foot Ulcer
Interventions
MatriStem® [Urinary Bladder Matrix (UBM)], Mepilex® [Silicone foam dressing]
Device
Lead sponsor
Calvary Hospital, Bronx, NY
Other
Eligibility
18 Years to 85 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 25, 2016 · Synced Oct 28, 2026, 2:32 AM EDT
Active, not recruiting Not applicable Interventional

Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends

NCT04865679
View directory record Official record
Conditions
Symptomatic Neuroma, Amputation, Chronic Nerve Pain
Interventions
Axoguard Nerve Cap®
Device
Lead sponsor
Axogen Corporation
Industry
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts • Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 28, 2026, 2:32 AM EDT