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ClinicalTrials.gov public records Last synced Oct 4, 2026, 3:04 PM EDT

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Showing 25–48 of 95 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Eyeglass lenses Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Is Y-Balance Test Predictive of Concussion

NCT05344703
View directory record Official record
Conditions
Concussion, Brain, Concussion; Eye
Interventions
Y Balance Plus Visual Perturbations, Y balance
Device · Diagnostic Test
Lead sponsor
Arkansas Colleges of Health Education
Other
Eligibility
11 Years to 19 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Fort Smith, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Oct 4, 2026, 3:04 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comprehensive Evaluation of Visual Function

NCT00894192
View directory record Official record
Conditions
Visual Function
Interventions
Izon Wavefront-guided lenses, Conventional lenses
Device
Lead sponsor
The Chicago Lighthouse
Other
Eligibility
18 Years to 35 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 6, 2009 · Synced Oct 4, 2026, 3:04 PM EDT
Terminated Not applicable Interventional Results available

Multifocal Visual Performance Study

NCT03757039
View directory record Official record
Conditions
Presbyopia
Interventions
Multifocal soft contact lenses, Progressive addition lens spectacles
Device · Other
Lead sponsor
Alcon Research
Industry
Eligibility
38 Years to 58 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 4, 2026, 3:04 PM EDT
Completed Phase 3 Interventional

Trial to Evaluate 2 Hours of Daily Patching for Amblyopia in Children

NCT00091923
View directory record Official record
Conditions
Amblyopia
Interventions
Eye patch, Spectacles
Device
Lead sponsor
Jaeb Center for Health Research
Other
Eligibility
3 Years to 7 Years
Enrollment
268 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
2
States / cities
Fullerton, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 24, 2010 · Synced Oct 4, 2026, 3:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study on Ambulatory Intraocular Pressure and Blood Pressure Monitoring in Glaucoma

NCT01912599
View directory record Official record
Conditions
Normal-Tension Glaucoma
Interventions
Sensimed Triggerfish, Blood Pressure
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 17, 2016 · Synced Oct 4, 2026, 3:04 PM EDT
Completed Not applicable Interventional

Thin Film Spectacle Coatings to Reduce Light Sensitivity and Headaches in Patients With Migraine

NCT01828684
View directory record Official record
Conditions
Migraine Disorders, Photophobia
Interventions
Therapeutic Lens Coating, Sham Lens Coating
Other
Lead sponsor
Bradley Katz
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 31, 2016 · Synced Oct 4, 2026, 3:04 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Spectacles Lens in Concussed Kids

NCT03123822
View directory record Official record
Conditions
Concussion, Mild, Convergence Insufficiency, Accommodation; Insufficiency
Interventions
Glasses
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
9 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 23, 2022 · Synced Oct 4, 2026, 3:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Light Sleep: Screen Use and Sleep Health

NCT05342662
View directory record Official record
Conditions
Glasses
Interventions
Blue light-blocking glasses, Glasses with clear lenses
Device
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 29 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Oct 4, 2026, 3:04 PM EDT
Terminated No phase listed Observational

Bilateral and Unilateral Amblyopia Treatment Study

NCT03780205
View directory record Official record
Conditions
Amblyopia
Interventions
Prescription glasses for bilateral amblyopia, Prescription glasses for unilateral amblyopia
Other
Lead sponsor
Salus University
Other
Eligibility
3 Years to 10 Years
Enrollment
1 participant
Timeline
2019 – 2020
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 31, 2020 · Synced Oct 4, 2026, 3:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Vision and Quality of Life in the Nursing Home

NCT00347620
View directory record Official record
Conditions
Refractive Error, Cataract
Interventions
spectacles, Cataract Surgery
Device · Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
60 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2003
U.S. locations
17
States / cities
Alabaster, Alabama • Bessemer, Alabama • Birmingham, Alabama + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2010 · Synced Oct 4, 2026, 3:04 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

CYPRESS Efficacy and Safety Study Extension

NCT04947735
View directory record Official record
Conditions
Juvenile Myopia, Myopia
Interventions
Novel spectacle lens design, Spectacle lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
11
States / cities
Whittier, California • Longwood, Florida • Pittsburg, Kansas + 8 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 4, 2026, 3:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Contact Lens Wear on Children's Self-Perceptions

NCT00522288
View directory record Official record
Conditions
Myopia
Interventions
Soft contact lenses, Spectacle
Device
Lead sponsor
Ohio State University
Other
Eligibility
8 Years to 11 Years
Enrollment
484 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
5
States / cities
Boston, Massachusetts • Columbus, Ohio • Forest Grove, Oregon + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2011 · Synced Oct 4, 2026, 3:04 PM EDT
Completed Not applicable Interventional

Post Marketing Clinical Study on the Efficacy of Lenses From a New Prescription Protocol

NCT07168564
View directory record Official record
Conditions
Ametropia, Refractive Error
Interventions
AVA lenses, Standard lenses
Device
Lead sponsor
Essilor International
Industry
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 4, 2026, 3:04 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Spectacle Independence and Overall Satisfaction With AcrySof® Panoptix® Toric Intraocular Lens

NCT04128514
View directory record Official record
Conditions
Cataract
Interventions
Panoptix Toric
Device
Lead sponsor
Eye Center of North Florida
Other
Eligibility
40 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Panama City, Florida
Source: ClinicalTrials.gov public record
Updated Apr 1, 2022 · Synced Oct 4, 2026, 3:04 PM EDT
Not yet recruiting Not applicable Interventional

Circadian Light Exposure Adjustment for Restfulness

NCT07391852
View directory record Official record
Conditions
Sleep Onset Latency
Interventions
Amber Tinted Glasses, Clear Glasses, Smart Lightbulbs
Device
Lead sponsor
University of Arizona
Other
Eligibility
60 Months to 83 Months
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 4, 2026, 3:04 PM EDT
Completed Phase 4 Interventional Results available

Symfony vs Vivity in Dim Light

NCT06229106
View directory record Official record
Conditions
Cataract
Interventions
Symfony IOL, Vivity IOL
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
50 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Sarasota, Florida • Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 14, 2025 · Synced Oct 4, 2026, 3:04 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Myopia:the Role of Cone Opsin Mutations & Glasses That Control Axial Elongation

NCT01923675
View directory record Official record
Conditions
Myopia
Interventions
Spectacles with red-blocking tint, Spectacles with holographic diffuser and color neutral tint, Spectacles with holographic diffuser and red-blocking tint, Spectacles with color neutral tint
Other
Lead sponsor
University of Washington
Other
Eligibility
8 Years to 13 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Oct 4, 2026, 3:04 PM EDT
Completed Phase 2 Interventional Results available

Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome

NCT05059041
View directory record Official record
Conditions
Down Syndrome, Refractive Errors
Interventions
Dilated Refraction, Non-Dilated Refraction
Device
Lead sponsor
Ohio State University
Other
Eligibility
5 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Columbus, Ohio • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 4, 2026, 3:04 PM EDT
Completed No phase listed Observational

Utility of a Survey Instrument to Predict Benefit From a Novel Treatment for Vertical Heterophoria

NCT01632787
View directory record Official record
Conditions
Binocular Vision Dysfunction, Vertical Heterophoria
Interventions
Questionnaires and Optometrist Prism Challenge/Treatment
Other
Lead sponsor
Vision Specialists of Birmingham
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Bloomfield Hills, Michigan • Livonia, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 1, 2017 · Synced Oct 4, 2026, 3:04 PM EDT
Not listed Not applicable Interventional

Monitored Controlled Intermittent Alternate Occlusion (CIAO) Therapy for Intermittent Exotropia

NCT02902887
View directory record Official record
Conditions
Intermittent Exotropia
Interventions
Controlled Intermittent Alternate Occlusion (CIAO ) glasses
Device
Lead sponsor
Salus University
Other
Eligibility
3 Years to 11 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2019 · Synced Oct 4, 2026, 3:04 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Impact of a Novel Extended Depth of Focus Intraocular Lens on Visual and Lifestyle Enhancement

NCT04570579
View directory record Official record
Conditions
Cataract, Cataract Senile, Presbyopia
Interventions
Vivity Extended Depth of Focus Intraocular Lens
Device
Lead sponsor
Alanna Nattis, DO
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Babylon, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Oct 4, 2026, 3:04 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Myopia Control With a Innovative Spectacle Lens - A Cessation Study

NCT06884527
View directory record Official record
Conditions
Myopia Progressing
Interventions
Single Vision Lens to A innovative spectacle lens
Device
Lead sponsor
Essilor International
Industry
Eligibility
9 Years to 15 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
5
States / cities
Chicago, Illinois • Pittsburg, Kansas • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 4, 2026, 3:04 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Clinical Investigation of the Vision-R800 Device.

NCT04208750
View directory record Official record
Conditions
Myopia, Hyperopia, Astigmatism, Presbyopia
Interventions
Vision R-800 Phoropter, Standard Phoropter
Device
Lead sponsor
Pete Kollbaum, OD, PhD
Other
Eligibility
18 Years to 70 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 14, 2022 · Synced Oct 4, 2026, 3:04 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neurolens and Contact Lens Discomfort

NCT05801991
View directory record Official record
Conditions
Contact Lens Discomfort
Interventions
Neurolens, Placebo spectacle lens
Device
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated Apr 22, 2025 · Synced Oct 4, 2026, 3:04 PM EDT