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ClinicalTrials.gov public records Last synced Oct 6, 2026, 4:34 PM EDT

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Showing 73–96 of 96 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Eyeglass lenses Clear all
Recruiting No phase listed Observational

Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy

NCT04310241
View directory record Official record
Conditions
Amblyopia, Strabismus
Interventions
Patching therapy, Glasses
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
6 Months to 90 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 6, 2026, 4:34 PM EDT
Terminated Not applicable Interventional Results available

Multifocal Visual Performance Study

NCT03757039
View directory record Official record
Conditions
Presbyopia
Interventions
Multifocal soft contact lenses, Progressive addition lens spectacles
Device · Other
Lead sponsor
Alcon Research
Industry
Eligibility
38 Years to 58 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 6, 2026, 4:34 PM EDT
Completed Phase 4 Interventional Results available

Symfony vs Vivity in Dim Light

NCT06229106
View directory record Official record
Conditions
Cataract
Interventions
Symfony IOL, Vivity IOL
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
50 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Sarasota, Florida • Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 14, 2025 · Synced Oct 6, 2026, 4:34 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Myopia:the Role of Cone Opsin Mutations & Glasses That Control Axial Elongation

NCT01923675
View directory record Official record
Conditions
Myopia
Interventions
Spectacles with red-blocking tint, Spectacles with holographic diffuser and color neutral tint, Spectacles with holographic diffuser and red-blocking tint, Spectacles with color neutral tint
Other
Lead sponsor
University of Washington
Other
Eligibility
8 Years to 13 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Oct 6, 2026, 4:34 PM EDT
Completed Not applicable Interventional Results available

Symfony Toric Intraocular Lens Visual Outcomes

NCT03082599
View directory record Official record
Conditions
Cataract Bilateral, Astigmatism Bilateral
Interventions
Presbyopia and astigmatism correcting intraocular lens
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
40 Years to 99 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
Stillwater, Minnesota • Garden City, New York • Mt. Pleasant, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 6, 2026, 4:34 PM EDT
Terminated Not applicable Interventional Results available

Spectacle Tints and Thin-Films for Migraine

NCT02720211
View directory record Official record
Conditions
Headache Migraine Chronic
Interventions
Gray tinted spectacle lenses, Thin-Film spectacle lenses
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
4
States / cities
Phoenix, Arizona • Boston, Massachusetts • Great Neck, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2022 · Synced Oct 6, 2026, 4:34 PM EDT
Completed No phase listed Observational

Utility of a Survey Instrument to Predict Benefit From a Novel Treatment for Vertical Heterophoria

NCT01632787
View directory record Official record
Conditions
Binocular Vision Dysfunction, Vertical Heterophoria
Interventions
Questionnaires and Optometrist Prism Challenge/Treatment
Other
Lead sponsor
Vision Specialists of Birmingham
Other
Eligibility
18 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Bloomfield Hills, Michigan • Livonia, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 1, 2017 · Synced Oct 6, 2026, 4:34 PM EDT
Terminated Phase 1Phase 2 Interventional

Enhancement of Emmetropization in Hyperopic Infants

NCT00574717
View directory record Official record
Conditions
Hyperopia, Hypermetropia, Farsightedness
Interventions
Spectacles
Procedure
Lead sponsor
Ohio State University
Other
Eligibility
8 Weeks to 20 Weeks
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 19, 2012 · Synced Oct 6, 2026, 4:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Seeing the World Through Assorted Glasses

NCT02483559
View directory record Official record
Conditions
Sleep
Interventions
Amber Lenses, Placebo Lenses
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 50 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 8, 2017 · Synced Oct 6, 2026, 4:34 PM EDT
Completed Not applicable Interventional Results available

Vivity IOL: Emmetropia Compared to Monovision.

NCT05464732
View directory record Official record
Conditions
Presbyopia
Interventions
Vivity IOL emmetropia, Vivity IOL monovision
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
50 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 24, 2025 · Synced Oct 6, 2026, 4:34 PM EDT
Completed Not applicable Interventional

Post Marketing Clinical Study on the Efficacy of Lenses From a New Prescription Protocol

NCT07168564
View directory record Official record
Conditions
Ametropia, Refractive Error
Interventions
AVA lenses, Standard lenses
Device
Lead sponsor
Essilor International
Industry
Eligibility
18 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 6, 2026, 4:34 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Spectacles Lens in Concussed Kids

NCT03123822
View directory record Official record
Conditions
Concussion, Mild, Convergence Insufficiency, Accommodation; Insufficiency
Interventions
Glasses
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
9 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 23, 2022 · Synced Oct 6, 2026, 4:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Myopia Assessment of Two Manufacturing Processes

NCT04126057
View directory record Official record
Conditions
Juvenile Myopia
Interventions
SightGlass Vision DOT Spectacle Lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 14 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
5
States / cities
Longwood, Florida • Pittsburg, Kansas • Raytown, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Oct 6, 2026, 4:34 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Children's Viewing Behavior

NCT07229365
View directory record Official record
Conditions
Myopia, Myopia Progression, Juvenile Myopia
Interventions
Novel spectacle lens design, Spectacle lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
7 Years to 14 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 6, 2026, 4:34 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Panoptix Trifocal Lens in Post Refractive Myopic Laser Vision Correction Surgery

NCT04698278
View directory record Official record
Conditions
Cataract, Refractive Errors
Interventions
PanOptix Trifocal Intraocular Lens
Device
Lead sponsor
Parkhurst NuVision Clinical Research LLC
Other
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Oct 6, 2026, 4:34 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Effectiveness of Orthokeratology in Decreasing Myopic Progression in a Young Adult Population Enrolled in a Professional Optometric Curriculum

NCT02623543
View directory record Official record
Conditions
Myopia Progression
Interventions
OrthoK
Device
Lead sponsor
Illinois College of Optometry
Other
Eligibility
20 Years to 40 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 7, 2015 · Synced Oct 6, 2026, 4:34 PM EDT
Completed Not applicable Interventional Results available

Post Approval Study of the AcrySof® IQ ReSTOR® Toric IOLs

NCT03733730
View directory record Official record
Conditions
Aphakia, Presbyopia, Astigmatism
Interventions
ACRYSOF IQ RESTOR +3.0 Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal IOL, Cataract Surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
2,449 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
37
States / cities
Dothan, Alabama • Phoenix, Arizona • Fresno, California + 32 more
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Oct 6, 2026, 4:34 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Evaluation of Quality of Vision and Spectacle Independence With the AcrySof® Panoptix® Intraocular Lens

NCT04124952
View directory record Official record
Conditions
Cataract
Interventions
Panoptix
Device
Lead sponsor
SightTrust Eye Institute
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Sunrise, Florida
Source: ClinicalTrials.gov public record
Updated Nov 22, 2023 · Synced Oct 6, 2026, 4:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Contact Lens Wear on Children's Self-Perceptions

NCT00522288
View directory record Official record
Conditions
Myopia
Interventions
Soft contact lenses, Spectacle
Device
Lead sponsor
Ohio State University
Other
Eligibility
8 Years to 11 Years
Enrollment
484 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
5
States / cities
Boston, Massachusetts • Columbus, Ohio • Forest Grove, Oregon + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2011 · Synced Oct 6, 2026, 4:34 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Neurolens Convergence Insufficiency Study

NCT05087563
View directory record Official record
Conditions
Binocular Vision Disorder, Convergence Insufficiency, Computer Vision Syndrome
Interventions
Neurolens spectacle lens, Placebo spectacle lens
Device
Lead sponsor
Neurolens Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
9
States / cities
Brea, California • Fort Collins, Colorado • Manchester, Connecticut + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2023 · Synced Oct 6, 2026, 4:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Myopia Control With a Innovative Spectacle Lens

NCT05174780
View directory record Official record
Conditions
Myopia
Interventions
innovative myopia control spectacle lens, Single vision spectacle lens
Device
Lead sponsor
Essilor International
Industry
Eligibility
6 Years to 12 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
9
States / cities
San Diego, California • Longwood, Florida • Chicago, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 6, 2026, 4:34 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Impact of a Novel Extended Depth of Focus Intraocular Lens on Visual and Lifestyle Enhancement

NCT04570579
View directory record Official record
Conditions
Cataract, Cataract Senile, Presbyopia
Interventions
Vivity Extended Depth of Focus Intraocular Lens
Device
Lead sponsor
Alanna Nattis, DO
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Babylon, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Oct 6, 2026, 4:34 PM EDT
Completed Not applicable Interventional Results available

The SleepWell Study - Chronotherapeutic Intervention to Improve Sleep Following ACS

NCT05299723
View directory record Official record
Conditions
Sleep Disturbance, Insomnia, Acute Coronary Syndrome
Interventions
BLT Intervention, BLB Intervention, Sleep Hygiene Education
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Oct 6, 2026, 4:34 PM EDT
Not listed Not applicable Interventional

Manual Small Incision Cataract Surgery Outcomes in an Educational Setting

NCT02277314
View directory record Official record
Conditions
Cataracts
Interventions
Manual Small Incision Cataract Surgery
Procedure
Lead sponsor
University of Arizona
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Oct 6, 2026, 4:34 PM EDT