Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Sep 26, 2026, 10:43 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 209 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Facial skin treatment Clear all
Completed Not applicable Interventional Results available

Evaluation of the Efficacy and Tolerance of a Light Therapy Mask on Mild to Moderate Brown Spots and Moderate to Severe Facial Wrinkles

NCT03312543
View directory record Official record
Conditions
Skin Aging
Interventions
Active Mask, Sham Mask
Device
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
35 Years to 70 Years · Female only
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Broomall, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 4, 2019 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Results available

Team-Based Connected Health (TCH) to Improve Clinical Outcomes and Access in Atopic Dermatitis

NCT03981926
View directory record Official record
Conditions
Atopic Dermatitis Eczema, Atopic Dermatitis, Eczema
Interventions
Team-Based Connected Health (TCH)
Other
Lead sponsor
University of Southern California
Other
Eligibility
1 Year and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy of 1550nm Fractional Laser Treatment for Acne Scars in Fitzpatrick Type IV-VI Skin

NCT00641420
View directory record Official record
Conditions
Acne Scarring
Interventions
Fractionated Laser Resurfacing
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 59 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 14, 2022 · Synced Sep 26, 2026, 10:43 AM EDT
Not listed Not applicable Interventional

Feasibility Study to Collect and Assess Safety Data for a Radiofrequency Microneedling Device for Electrocoagulation and Hemostasis of Soft Tissues for Dermatologic Conditions

NCT05987319
View directory record Official record
Conditions
Wrinkle, Fine Lines, Crepey Skin, Acne Scars, Active Acne, Enlarged Pores, Stretch Mark, Loose Skin
Interventions
RadioFrequency Microneedling Device
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
22 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Westford, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Wrinkles Around the Eyes Using the Ulthera® System

NCT01368900
View directory record Official record
Conditions
Periorbital Wrinkles
Interventions
Ulthera® System treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
2
States / cities
Hunt Valley, Maryland • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional

Clinical Trial to Assess the Effects of Topical Lotions on Changes in the Skin Microbiome and Associations With Itch

NCT03673059
View directory record Official record
Conditions
Microbiota
Interventions
OTC Eczema Moisturizer Regimen, Cosmetic Moisturizer Regimen
Drug · Other
Lead sponsor
Johnson & Johnson Consumer Products Company Division of Johnson & Johnson Consumer Companies, Inc.
Industry
Eligibility
16 Years to 50 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Colorado Springs, Colorado • Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2018 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Phase 2 Interventional

Study to Evaluate the Safety and Efficacy of Topical Minocycline Gel in Patients With Papulopustular Rosacea

NCT03263273
View directory record Official record
Conditions
Rosacea, Papulopustular Rosacea
Interventions
1% Topical Minocycline Gel, 3% Topical Minocycline Gel, Topical Vehicle Gel
Drug · Other
Lead sponsor
Hovione Scientia Limited
Industry
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
23
States / cities
Bryant, Arkansas • Rogers, Arkansas • Fremont, California + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 7, 2019 · Synced Sep 26, 2026, 10:43 AM EDT
Withdrawn Phase 2 Interventional

Open-label, Single-arm, Proof of Concept Study in Subjects with Mild-to-moderate Facial Hyperpigmentation

NCT06473974
View directory record Official record
Conditions
Facial Hyperpigmentation
Interventions
Test cosmetic product
Drug
Lead sponsor
Kayuraeffect, LLP
Industry
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
2
States / cities
Miami Lakes, Florida • New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 15, 2024 · Synced Sep 26, 2026, 10:43 AM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Safety Study of Bone Marrow Derived Stem Cells on Patients With Cutaneous Photoaging

NCT01771679
View directory record Official record
Conditions
Chronic Effect of Ultraviolet Radiation on Photoaged Skin, Dermatologic Disorders
Interventions
Allogeneic Mesenchymal Bone Marrow Cells
Biological
Lead sponsor
Stemedica Cell Technologies, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2024
U.S. locations
2
States / cities
La Mesa, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 30, 2022 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Poly-L-lactic Acid for Skin Quality

NCT02003833
View directory record Official record
Conditions
Skin Aging
Interventions
Poly-L-lactic acid, Placebo comparator
Device
Lead sponsor
Sadick Research Group
Other
Eligibility
30 Years to 60 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
2
States / cities
Carmel, Indiana • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 19, 2015 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

In-vivo Analysis and Clinical Evaluation of the Performance of a Fractional CO2 Laser System (eMatrixCO2)

NCT00992277
View directory record Official record
Conditions
Aesthetic Dermatology
Interventions
Ablation and skin resurfacing
Procedure
Lead sponsor
Syneron Medical
Industry
Eligibility
20 Years to 60 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
3
States / cities
San Diego, California • Tustin, California • Saint Edina, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 1, 2014 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles

NCT03776461
View directory record Official record
Conditions
Rhytides, Wrinkle
Interventions
Venus Viva
Device
Lead sponsor
Venus Concept
Industry
Eligibility
22 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Phase 3 Interventional

S-Caine™ Peel (Skin Numbing Cream) to Treat Pain During Skin Filler Injection in the Face

NCT00110760
View directory record Official record
Conditions
Pain
Interventions
S-Caine™ Peel (lidocaine and tetracaine cream 7%/7%), Placebo Peel
Drug
Lead sponsor
ZARS Pharma Inc.
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
3
States / cities
Englewood, Colorado • Nashville, Tennessee • Bryan, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2012 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Examine the Effects of Cosmeceutical Therapy in Subjects Undergoing Full Facial Rejuvenation

NCT02726451
View directory record Official record
Conditions
Facial Rejuvenation With Neurotoxins and/or Hyaluronic Acid Fillers
Interventions
Basic Skin Care, Active Skin Care
Other
Lead sponsor
DeNova Research
Other
Eligibility
21 Years to 60 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Sep 26, 2026, 10:43 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Venus Versa Diamondpolar Applicator Treatment Followed by AC Dual Applicator Treatment for Facial Acne Vulgaris

NCT02924428
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Venus Versa
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years to 55 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 8, 2020 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Phase 4 Interventional

A Clinical Study to Assess Efficacy and Tolerability of a Topical Skincare Product on Adults With Mature, Crepey Skin

NCT07398989
View directory record Official record
Conditions
Crepey Skin, Aging Skin, Photo-aged Skin
Interventions
Cetaphil
Drug
Lead sponsor
Galderma R&D
Industry
Eligibility
40 Years to 60 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Manhattan Beach, California • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

TriActive+ Radiofrequency (RF) for Non-invasive Treatment of Wrinkles & Rhytides

NCT01460927
View directory record Official record
Conditions
Wrinkles, Rhytides
Interventions
TriActive+ RF
Device
Lead sponsor
Deka Medical, Inc.
Industry
Eligibility
30 Years to 60 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Vancouver, Washington
Source: ClinicalTrials.gov public record
Updated Jul 3, 2014 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Phase 2 Interventional Results available

An Evaluation of the Adrenal Suppression Potential and PK of CB-03-01 Cream in Pediatric Patients With Acne Vulgaris

NCT02720627
View directory record Official record
Conditions
Acne Vulgaris
Interventions
cortexolone 17α-propionate
Drug
Lead sponsor
Cassiopea SpA
Industry
Eligibility
9 Years to 11 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
3
States / cities
Fort Smith, Arkansas • San Diego, California • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Investigation of Safety and Effectiveness of Emerald IPLdevice

NCT03945383
View directory record Official record
Conditions
Hair Removal
Interventions
Treatment with IPL device
Device
Lead sponsor
Philips Healthcare
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
3
States / cities
Miami, Florida • Chicago, Illinois • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Sep 26, 2026, 10:43 AM EDT
Not yet recruiting Phase 2Phase 3 Interventional

Skin Care Regimen for Improving Photoaging Signs on the Face

NCT06603857
View directory record Official record
Conditions
Improve Photoaging Signs
Interventions
CE Ferulic, Sham Comparator, 1927nm (Clear and Brilliant Perméa®)
Drug · Device
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
30 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Collaborative Connected Health (CCH) for PCORI

NCT02358135
View directory record Official record
Conditions
Psoriasis
Interventions
Collaborative Connected health, (CCH), Control
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
3
States / cities
Los Angeles, California • Sacramento, California • Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Phase 1Phase 2 Interventional Results available

A Study to Evaluate the Clinical Effect of Daily Next Science™ Acne Gel (NAG) on Mild to Moderate Facial Acne

NCT02404285
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Next Science Acne Gel, Vehicle
Drug
Lead sponsor
Next Science TM
Industry
Eligibility
12 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
3
States / cities
Jacksonville, Florida • Ponte Vedra, Florida
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Sep 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Efficacy of Single Therapy Versus Double and Triple Therapy of the Pellevé™ Wrinkle Treatment System for the Treatment of Moderate Facial Wrinkles

NCT01299103
View directory record Official record
Conditions
Appearance of Facial Wrinkles
Interventions
Pelleve Wrinkle Treatment System
Device
Lead sponsor
Ellman International
Industry
Eligibility
35 Years to 60 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chichago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Sep 26, 2026, 10:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Skin Hydration and Facial Aging in Women Aged 30-60: An Observational Correlational Study Using Bioimpedance Analysis

NCT07564869
View directory record Official record
Conditions
Skin Aging, Skin Hydration, Facial Aging, Transepidermal Water Loss
Interventions
BT-Analyze Bioimpedance Measurement
Other
Lead sponsor
IAS Skin Care
Industry
Eligibility
30 Years to 60 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Winter Garden, Florida
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 26, 2026, 10:43 AM EDT