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ClinicalTrials.gov public records Last synced Oct 6, 2026, 11:21 PM EDT

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Showing 49–72 of 211 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Facial skin treatment Clear all
Completed Not applicable Interventional

Comparison of the RevLite Electro-optic Q-Switched Neodymium-doped Yttrium Aluminium Garnet (EO QS Nd:YAG) Laser to a Fractionated Laser System

NCT00955461
View directory record Official record
Conditions
Photodamage, Irregular Pigmentation, Acne Scars
Interventions
RevLite laser treatment, Fractionated Laser treatment
Procedure
Lead sponsor
ConBio, a Cynosure Company
Industry
Eligibility
25 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 28, 2012 · Synced Oct 6, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Aldena STAR Particles

NCT06004973
View directory record Official record
Conditions
Healthy
Interventions
STAR Particles, Gel without STAR Particles
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 39 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 6, 2026, 11:21 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Epidermal Delivery of Ani-Aging Ingredients

NCT01847066
View directory record Official record
Conditions
Wrinkles, Acne Scars, Pigmentation
Interventions
Erbium 2940 plus cosmetics plus Impact, Erbium 2940 plus cosmetics
Device
Lead sponsor
Alma Lasers Inc.
Industry
Eligibility
35 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2013 · Synced Oct 6, 2026, 11:21 PM EDT
Terminated Phase 3 Interventional Results available

Combination Therapy With 5-Fluorouracil and Photodynamic Therapy in Post-transplant Premalignant Skin Disease

NCT01525329
View directory record Official record
Conditions
Actinic Keratosis, Organ or Tissue Transplant; Complications
Interventions
5-Fluorouracil
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 15, 2022 · Synced Oct 6, 2026, 11:21 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Treatment to Lift Facial Lax Skin and Improve Facial Wrinkles Using Precise and Lift Applicators

NCT06333067
View directory record Official record
Conditions
Lax Skin
Interventions
Sofwave
Device
Lead sponsor
Sofwave Medical LTD
Industry
Eligibility
35 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
La Mesa, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Oct 6, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pulsed Dye Laser (PDL) vs. Microsecond 1064-nm Nd:YAG Laser for Treatment of Diffuse Facial Redness

NCT01529996
View directory record Official record
Conditions
Rosacea
Interventions
Pulse Dye Laser/YAG laser
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 2, 2021 · Synced Oct 6, 2026, 11:21 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Fractional Laser vs. Ultrasound for Periorbital Wrinkles

NCT01529983
View directory record Official record
Conditions
Wrinkles
Interventions
Laser treatment, High-intensity focused ultrasound
Procedure · Device
Lead sponsor
Northwestern University
Other
Eligibility
35 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 6, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Multi-Center, Open-label Study Evaluate the Efficacy and Tolerability of a Dual Skincare Regimen Treatment for Facial Hyperpigmentation and Photodamaged Skin in Patients Exposed to Extrinsic Factors of Aging

NCT05423873
View directory record Official record
Conditions
Hyperpigmentation, Photodamaged Skin, Wrinkle, Fine Lines
Interventions
Gentle Cleansing Lotion, Revision Skincare
Other
Lead sponsor
Revision Skincare
Industry
Eligibility
35 Years to 60 Years · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
3
States / cities
Solana Beach, California • Greenwood Village, Colorado • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Oct 6, 2026, 11:21 PM EDT
Completed Phase 4 Interventional Results available

Efficacy and Safety Study of Finacea to Treat Acne Vulgaris and Post-Inflammatory Hyperpigmentation (PIH)

NCT01038869
View directory record Official record
Conditions
Acne Vulgaris, Post Inflammatory Hyperpigmentation
Interventions
Azelaic acid
Drug
Lead sponsor
Derm Research, PLLC
Other
Eligibility
12 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 25, 2012 · Synced Oct 6, 2026, 11:21 PM EDT
Not listed Not applicable Interventional

Lymphedema Treatment for Blunt Facial Trauma

NCT02977182
View directory record Official record
Conditions
Post-traumatic Facial Edema
Interventions
Complete Decongestive Therapy (CDT)
Other
Lead sponsor
Our Lady of the Lake Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 30, 2016 · Synced Oct 6, 2026, 11:21 PM EDT
Completed Not applicable Interventional Results available

A Pilot Study to Evaluate the Safety and Effectiveness of Microneedling and Bellafill to Treat Facial Acne Scars

NCT02643628
View directory record Official record
Conditions
Atrophic Acne Scars
Interventions
Microneedling, Microneedling followed by Bellafill treatment
Procedure · Device
Lead sponsor
Suneva Medical, Inc.
Industry
Eligibility
21 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 28, 2019 · Synced Oct 6, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Study Evaluating the Efficacy and Tolerability of a Topical Facial Treatment For Facial Rejuvenation

NCT06629792
View directory record Official record
Conditions
Fine Lines, Wrinkles, Laxity; Skin
Interventions
Gentle Cleanser, Facial Moisturizer, sunscreen SPF 30
Other
Lead sponsor
Revision Skincare
Industry
Eligibility
35 Years to 60 Years · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Oct 6, 2026, 11:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Skin Hydration and Facial Aging in Women Aged 30-60: An Observational Correlational Study Using Bioimpedance Analysis

NCT07564869
View directory record Official record
Conditions
Skin Aging, Skin Hydration, Facial Aging, Transepidermal Water Loss
Interventions
BT-Analyze Bioimpedance Measurement
Other
Lead sponsor
IAS Skin Care
Industry
Eligibility
30 Years to 60 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Winter Garden, Florida
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 6, 2026, 11:21 PM EDT
Withdrawn Not applicable Interventional

Efficacy of Pulsed Light Therapy for Meibomian Gland Dysfunction and Dry Eye Syndrome

NCT01917539
View directory record Official record
Conditions
Meibomian Gland Dysfunction, Dry Eye Syndrome
Interventions
Sham Treatment, Pulsed Light Therapy
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 28, 2018 · Synced Oct 6, 2026, 11:21 PM EDT
Completed Phase 3 Interventional Results available

Multicenter Study to Assess the Efficacy and Safety of Methyl Aminolevulinate Hydrochloride (MAL) 16.8% Cream (CD06809-41) Versus Vehicle Cream for Actinic Keratosis of the Face

NCT04085367
View directory record Official record
Conditions
Actinic Keratoses
Interventions
MAL 16.8% cream, MAL Vehicle Cream
Drug
Lead sponsor
Galderma R&D
Industry
Eligibility
18 Years and older
Enrollment
557 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
59
States / cities
Tucson, Arizona • Fort Smith, Arkansas • Encinitas, California + 52 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2022 · Synced Oct 6, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of a Novel Laser for Skin Rejuvenation

NCT02910492
View directory record Official record
Conditions
Rejuvenation
Interventions
enLighten Laser
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Brisbane, California • Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 15, 2023 · Synced Oct 6, 2026, 11:21 PM EDT
Terminated Phase 2 Interventional Results available

Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex

NCT03363763
View directory record Official record
Conditions
Angiofibroma of Face, Tuberous Sclerosis
Interventions
Sirolimus 0.2%, Sirolimus 0.4%, Placebo ointment
Drug
Lead sponsor
Aucta Pharmaceuticals, Inc
Industry
Eligibility
2 Years to 21 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
7
States / cities
Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Oct 6, 2026, 11:21 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Venus Versa Diamondpolar Applicator Treatment Followed by AC Dual Applicator Treatment for Facial Acne Vulgaris

NCT02924428
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Venus Versa
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years to 55 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 9, 2020 · Synced Oct 6, 2026, 11:21 PM EDT
Completed Phase 3 Interventional

S-Caine™ Peel (Skin Numbing Cream) to Treat Pain During Skin Filler Injection in the Face

NCT00110760
View directory record Official record
Conditions
Pain
Interventions
S-Caine™ Peel (lidocaine and tetracaine cream 7%/7%), Placebo Peel
Drug
Lead sponsor
ZARS Pharma Inc.
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
3
States / cities
Englewood, Colorado • Nashville, Tennessee • Bryan, Texas
Source: ClinicalTrials.gov public record
Updated Jun 5, 2012 · Synced Oct 6, 2026, 11:21 PM EDT
Completed Phase 1 Interventional Results available

Daylight Photodynamic Therapy for Actinic Keratosis

NCT03322293
View directory record Official record
Conditions
Actinic Keratoses
Interventions
Aminolevulinic Acid Topical 20% Topical Solution, BLU-U blue light phototherapy illuminator
Drug · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Oct 6, 2026, 11:21 PM EDT
Terminated Phase 1 Interventional Results available

Novel Antiaging Regenerative Skin Care Regimen Containing Human Platelet Extract (HPE)

NCT05457491
View directory record Official record
Conditions
Skin Aging
Interventions
Human platelet extract (cosmetic product), Vanicream Gentle Facial Cleanser, EltaMD UV Daily Broad-Spectrum SPF 40, EltaMD PM Therapy Facial Moisturizer, Vanicream Lite Lotion
Biological · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 6, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles

NCT03831477
View directory record Official record
Conditions
Rhytides, Wrinkle
Interventions
Venus Viva
Device
Lead sponsor
Venus Concept
Industry
Eligibility
22 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Oct 6, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Lifting and Tightening of the Face in Subjects With Skin of Darker Color

NCT01368965
View directory record Official record
Conditions
Facial Skin Laxity
Interventions
Ulthera® System treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
30 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
2
States / cities
Chevy Chase, Maryland • Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 13, 2017 · Synced Oct 6, 2026, 11:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Safety and Efficacy of Micro-coring Device for Treatment of Facial Wrinkles and Skin Laxity

NCT03228641
View directory record Official record
Conditions
Wrinkle, Facial and Neck Skin Laxity
Interventions
micro-excisional skin removal with coring needle
Device
Lead sponsor
Cytrellis Biosystems, Inc.
Industry
Eligibility
40 Years to 75 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
6
States / cities
Sacramento, California • Miami, Florida • Chestnut Hill, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 6, 2026, 11:21 PM EDT