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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Flavonoids Clear all
Enrolling by invitation Phase 2 Interventional

Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Women

NCT03430037
View directory record Official record
Conditions
Frail Elderly Syndrome
Interventions
Fisetin, Placebo oral capsule
Dietary Supplement · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
70 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Relative Bioavailability Study of 100 mg Flavoxate Hydrochloride Tablets Under Fasting Conditions

NCT00992238
View directory record Official record
Conditions
Healthy
Interventions
Flavoxate Hydrochloride Tablets, 100mg, Urispas® Tablets, 100mg
Drug
Lead sponsor
Padagis LLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Jul 9, 2023 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Phase 1 Interventional

Targeting Pro-Inflammatory Cells in Idiopathic Pulmonary Fibrosis: a Human Trial

NCT02874989
View directory record Official record
Conditions
Idiopathic Pulmonary Fibrosis (IPF)
Interventions
Dasatinib + Quercetin, Placebo
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
50 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Winston-Salem, North Carolina • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Sep 9, 2026, 1:41 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Flavonoids in the Treatment of Endothelial Dysfunction in Children With Diabetes

NCT01307917
View directory record Official record
Conditions
Diabetic Nephropathy, Endothelial Dysfunction
Interventions
flavonoids
Dietary Supplement
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Amarillo, Texas
Source: ClinicalTrials.gov public record
Updated Dec 16, 2012 · Synced Sep 9, 2026, 1:41 PM EDT
Enrolling by invitation Phase 2 Interventional

Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Adults

NCT03675724
View directory record Official record
Conditions
Frail Elderly Syndrome
Interventions
Fisetin, Placebo oral capsule
Dietary Supplement · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
70 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Cocoa Shot on the Human Brain

NCT01924481
View directory record Official record
Conditions
Caffeine, Flavonoids
Interventions
High Caffeine, Low caffeine, High theobromine, low theobromine, No theobromine
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 38 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Genistein in Preventing Breast or Endometrial Cancer in Healthy Postmenopausal Women

NCT00099008
View directory record Official record
Conditions
Breast Cancer, Endometrial Cancer
Interventions
Genistein, Placebo
Dietary Supplement
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
45 Years to 70 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 20, 2013 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Absorption, Metabolism and Excretion of Dietary Polyphenolic Bioactives in Humans

NCT03194620
View directory record Official record
Conditions
Healthy
Interventions
Thearubigins, Theaflavins, Procyanidin Dimer B2 (DB2), (-)-Epigallocatechin-3-O-gallate (EGCG), (-)-Epicatechin-3-O-gallate (ECG), (-)-Epicatechin (EC), (-)-Epigallocatechin (EGC), Control
Other
Lead sponsor
University of California, Davis
Other
Eligibility
25 Years to 60 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Senolytic Therapy to Modulate Progression of Alzheimer's Disease

NCT04063124
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Dasatinib + Quercetin
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
65 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 5, 2023 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Phase 2 Interventional

Phytoestrogens and Memory Decline in Menopause

NCT00051402
View directory record Official record
Conditions
Memory Loss, Postmenopause
Interventions
Isoflavones
Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
62 Years and older · Female only
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 25, 2007 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Botanical/Drug Interactions in HIV: Glucuronidation

NCT00065741
View directory record Official record
Conditions
HIV Seronegativity
Interventions
silymarin
Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2007 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Exercise, Milk Thistle, and Lactobacillus to Influence Plasma Bilirubin

NCT04717726
View directory record Official record
Conditions
Obesity
Interventions
Milk Thistle (MT), Lactobacillus Gasseri (LAC), Exercise (EX), Control (CON)
Dietary Supplement · Behavioral
Lead sponsor
Kyle Flack
Other
Eligibility
18 Years to 50 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Sep 9, 2026, 1:41 PM EDT
Terminated Phase 2 Interventional Results available

Intravenous Milk Thistle (Silibinin-Legalon) for Hepatic Failure Induced by Amatoxin/Amanita Mushroom Poisoning

NCT00915681
View directory record Official record
Conditions
Amatoxin Poisoning, Amanita Poisoning, Mushroom Poisoning, Liver Failure
Interventions
Silibinin
Drug
Lead sponsor
Mylan Specialty, LP
Industry
Eligibility
Not listed
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2020
U.S. locations
2
States / cities
Somerset, New Jersey • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Apr 6, 2022 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Three New Ideas to Protect Special Forces From the Stress of High Altitude

NCT02463357
View directory record Official record
Conditions
Mountain Sickness
Interventions
Quercetin, Nifedipine extended release, Methazolamide, Metformin, Placebo, Nitrite
Dietary Supplement · Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Alma, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 29, 2021 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Combined Exercise, Heat, and Quercetin Supplementation on Whole Body Stress Response

NCT01168739
View directory record Official record
Conditions
Heat Acclimation and Thermotolerance
Interventions
Quercetin, Placebo
Dietary Supplement
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 39 Years · Male only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

The Effect of Milk Thistle on the Pharmacokinetics of Indinavir

NCT00011635
View directory record Official record
Conditions
HIV Infection, Healthy
Interventions
Silymarin (milk thistle)
Drug
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Flavonoid Effect on Activation and Stimulation of Thrombocytes, hsCRP and Lipid Profile

NCT00559663
View directory record Official record
Conditions
Healthy
Interventions
Green tea, 70% dark chocolate
Dietary Supplement
Lead sponsor
LifeBridge Health
Other
Eligibility
18 Years to 55 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 19, 2007 · Synced Sep 9, 2026, 1:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers Results available

Carotenoid and Flavonoid Absorption From Red and Tangerine-Type Tomatoes

NCT01696773
View directory record Official record
Conditions
Carotenoid and Flavonoid Absorption
Interventions
Tangerine tomato juice, Red tomato juice
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Not applicable Interventional

Study of Flavocoxid (Limbrel) vs Naproxen in Subjects With Mod-Severe Osteoarthritis of the Knee

NCT00435292
View directory record Official record
Conditions
Osteoarthritis
Interventions
Naproxen, flavocoxid 250 mg, flavocoxid 500 mg
Drug · Dietary Supplement
Lead sponsor
Primus Pharmaceuticals
Industry
Eligibility
35 Years to 85 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 20, 2015 · Synced Sep 9, 2026, 1:41 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Observational Study on the Use of Ivermectin as an Outpatient Treatment Option for COVID-19

NCT05045937
View directory record Official record
Conditions
Covid19, COVID-19 Pneumonia, COVID-19 Respiratory Infection, COVID-19 Acute Bronchitis
Interventions
Ivermectin
Drug
Lead sponsor
Patrick Robinson
Other
Eligibility
12 Years to 110 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Antonio, Florida
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Sep 9, 2026, 1:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Efficacy of a Tea Catechin Sports Drink for Enhancing Exercise-Induced Fat Loss

NCT00692731
View directory record Official record
Conditions
Overweight, Obesity
Interventions
500 mL/day of a beverage providing approximately 625 mg catechins, Control beverage matched for energy and caffeine content
Dietary Supplement · Other
Lead sponsor
Provident Clinical Research
Other
Eligibility
21 Years to 65 Years
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
2
States / cities
St. Petersburg, Florida • Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 5, 2008 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Phase 1 Interventional

A Pharmacokinetic Study of Genistein, a Tyrosine Kinase Inhibitor

NCT00001696
View directory record Official record
Conditions
Cancer
Interventions
Genistein
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 9, 2026, 1:41 PM EDT
Terminated Not applicable Interventional

Isoflavones in Treating Women Who Have Breast Cancer and Are Planning to Undergo Mastectomy or Lumpectomy

NCT00036686
View directory record Official record
Conditions
Breast Cancer
Interventions
Soy protein isolate, Placebo
Dietary Supplement · Other
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
7
States / cities
Phoenix, Arizona • Tampa, Florida • Savannah, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2012 · Synced Sep 9, 2026, 1:41 PM EDT
Completed Not applicable Interventional

Study of Flavocoxid (Limbrel) Versus Naproxen in Subjects With Moderate-Severe Osteoarthritis of the Knee

NCT00928837
View directory record Official record
Conditions
Osteoarthritis
Interventions
Flavocoxid 500 mg, Naproxen, Placebo, flavocoxid 250 mg
Dietary Supplement · Drug · Other
Lead sponsor
Primus Pharmaceuticals
Industry
Eligibility
35 Years to 85 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Duncansville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Sep 9, 2026, 1:41 PM EDT