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ClinicalTrials.gov public records Last synced Sep 26, 2026, 1:48 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Flavor additives Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Cigar Flavor in Dual Users

NCT04487470
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Flavored filtered cigars, Unflavored filtered cigars
Other
Lead sponsor
UConn Health
Other
Eligibility
21 Years to 34 Years
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Sep 26, 2026, 1:48 AM EDT
Not yet recruiting Not applicable Interventional

The EDICT Trial - Therapy for Inflammatory Bowel Disease Flares

NCT07143188
View directory record Official record
Conditions
Inflammatory Bowel Disease
Interventions
elemental diet (ED)
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 26, 2026, 1:48 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Neo40(TM) With Caffeine on Cycling Time Trial Performance

NCT01710761
View directory record Official record
Conditions
Healthy
Interventions
Placebo, Nitrate supplement with caffeine
Dietary Supplement
Lead sponsor
University of Texas at Austin
Other
Eligibility
21 Years to 49 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2013 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Phase 1 Interventional Results available

University of Alabama at Birmingham (UAB) Pediatric CBD Program

NCT02695537
View directory record Official record
Conditions
Epilepsy, Seizures
Interventions
Epidiolex
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Year to 19 Years
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 9, 2020 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of E-Cigarettes in Menthol Smokers

NCT05949034
View directory record Official record
Conditions
E-cigarette Use, Smoking Behaviors
Interventions
JUUL E-Cigarette Device
Device
Lead sponsor
University of Southern California
Other
Eligibility
21 Years and older
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 19, 2023 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Phase 1Phase 2 Interventional

The Role of Nicotine and Non-Nicotine Alkaloids in E-Cigarette Use and Dependence

NCT02590393
View directory record Official record
Conditions
Nicotine Dependence
Interventions
E-cigarettes
Combination Product
Lead sponsor
Duke University
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Sep 26, 2026, 1:48 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Oral Rehydration Solutions in Healthy Adult Athletes

NCT05569044
View directory record Official record
Conditions
Hydration
Interventions
Control Group, Oral Rehydration Solution, Water
Other
Lead sponsor
Abbott Nutrition
Industry
Eligibility
18 Years to 30 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Kent, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Water Content in E-Liquids

NCT05257109
View directory record Official record
Conditions
Nicotine E-Cigarette Use
Interventions
Water Concentration 1, Water Concentration 2, Water Concentration 3, Water Concentration 4
Other
Lead sponsor
Yale University
Other
Eligibility
21 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing the Effect of Flavor on ENDS Users' Experiences and Exposures

NCT04192032
View directory record Official record
Conditions
Electronic Cigarette Use
Interventions
Preferred Juul pod flavor (5% nicotine), Classic Tobacco Juul pod flavor (5% nicotine), Preferred flavor with HWL, Preferred flavor, 3% nicotine, Preferred flavor, 0% nicotine
Other
Lead sponsor
Florida International University
Other
Eligibility
18 Years to 24 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assess Biomarkers of Tobacco Exposure and Nicotine Pharmacokinetics in Smokers After a 5-Day In-Clinic Confinement Switch to an Electronic Cigarette or Nicotine Gum

NCT02323438
View directory record Official record
Conditions
Smoking
Interventions
Usual Brand Cigarette, Electronic Cigarette #1, Electronic Cigarette #2, Leading U.S. Nicotine Gum
Other
Lead sponsor
R.J. Reynolds Vapor Company
Industry
Eligibility
21 Years to 60 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 31, 2018 · Synced Sep 26, 2026, 1:48 AM EDT
Recruiting Not applicable Interventional

Effects of Ketone Ester Consumption on Exercise Tolerance and Cardiac Function

NCT06078683
View directory record Official record
Conditions
Type 2 Diabetes, Ketone Body Metabolism, Ketones, Metabolism
Interventions
Ketone Ester Acute, Placebo Acute
Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Sep 26, 2026, 1:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Using Nicotine to Reverse Age-related Auditory Processing Deficits

NCT04971954
View directory record Official record
Conditions
Auditory Perceptual Impairment, Aging
Interventions
Nicotine gum, Placebo gum
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 26, 2026, 1:48 AM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

Study of the Effects of an Oral Nitric Oxide Supplement on Blood Pressure in Prehypertensive Adults

NCT01937754
View directory record Official record
Conditions
Prehypertension
Interventions
Nitric Oxide supplement, Placebo
Dietary Supplement
Lead sponsor
Neogenis Laboratories
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Sep 9, 2013 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Results available

Effects of Cigarette and E-cigarette Flavors on Substitutability in the ETM

NCT06910202
View directory record Official record
Conditions
Cigarette Smoking Behavior
Interventions
Manipulation of nicotine/tobacco product price and availability
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
21 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 26, 2026, 1:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Abuse Liability and Appeal of Oral Nicotine Products

NCT06506162
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Flavor, Nicotine concentration
Other
Lead sponsor
University of Southern California
Other
Eligibility
21 Years to 25 Years
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Micronutrients to Prevent Noise-induced Hearing Loss

NCT00808470
View directory record Official record
Conditions
Noise-Induced Hearing Loss
Interventions
beta-carotene, vitamins C and E, magnesium, Placebo
Drug · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 35 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 18, 2017 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Do Flavors Increase the Addiction Potential of Nicotine?

NCT04696380
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Nicotine, JUUL e-cigarette
Drug · Device
Lead sponsor
University of Vermont
Other
Eligibility
21 Years and older
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional

Nicotine Pharmacokinetics and Subjective Effects of Oral Nicotine Products Relative to Smokeless Tobacco in Adult Users

NCT06691386
View directory record Official record
Conditions
Tobacco Use
Interventions
Test Product A, Test Product B, Test Product C, Test Product D, Test Product E, Reference Product F: Subjects' OBMST
Other
Lead sponsor
Altria Client Services LLC
Industry
Eligibility
22 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Bentonville, Arkansas • Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 16, 2025 · Synced Sep 26, 2026, 1:48 AM EDT
Recruiting Not applicable Interventional

Feasibility and Potential Efficacy of Herbs and Spices for Improving Dietary Quality in College Students: A Pilot Study

NCT07082348
View directory record Official record
Conditions
Dietary Quality, Feasibility Studies, College Student, Dietary Guidelines for Americans, Gut Microbiome, Lipid Profiles, Herbs and Spices, Acceptability, Inflammation Biomarkers, Body Composition, Anthropometrics
Interventions
Herbs and Spices Nutrition Education Program
Behavioral
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 39 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 26, 2026, 1:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Postprandial Effects of Fresh Mango as a Table Sugar Replacement in High-Sugar Breakfasts.

NCT07650058
View directory record Official record
Conditions
Healthy Participants
Interventions
High-Glycemic Breakfast Containing Cereal and Fresh Mango, High-Glycemic Breakfast Containing Cereal and Table Sugar
Other
Lead sponsor
Ball State University
Other
Eligibility
18 Years to 45 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Muncie, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of a Dietary Supplement on Quality of Life

NCT05323084
View directory record Official record
Conditions
Quality of Life
Interventions
Dietary supplement
Dietary Supplement
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
50 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 15, 2024 · Synced Sep 26, 2026, 1:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Watermelon on Cardiometabolic Health

NCT07006636
View directory record Official record
Conditions
Cardiometabolic Health Indicators, Whole-body Antioxidant Capacity
Interventions
Watermelon Juice + liquid meal test at baseline, Sweetened placebo beverage +liquid meal test at baseline
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Sep 26, 2026, 1:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco Users

NCT02102100
View directory record Official record
Conditions
Nicotine Dependence
Interventions
nicotine, menthol
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 30 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Sep 26, 2026, 1:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Targeted Assessment of Cognition and Tactical-performance With Ingested Ketones

NCT07771790
View directory record Official record
Conditions
Cognition
Interventions
KetoneIQ®, Placebo
Dietary Supplement
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 26, 2026, 1:48 AM EDT