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Showing 1–24 of 33 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional

Does Flaxseed Supplementation Improve Glycemic Control in Individuals With Pre-diabetes?

NCT01698112
View directory record Official record
Conditions
PreDiabetes
Interventions
Flaxseed High Dose, Flaxseed Low Dose
Dietary Supplement
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
50 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
2
States / cities
Colorado Springs, Colorado • Missoula, Montana
Source: ClinicalTrials.gov public record
Updated Oct 1, 2012 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Omega-3 Fatty Acids on Markers of Inflammation

NCT01129050
View directory record Official record
Conditions
Obesity, Hypertriglyceridemia, Insulin Resistance, Hypertension
Interventions
Fish Oil, Flaxseed Oil, Placebo
Dietary Supplement
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study of SIAN Nasal Spray in Healthy Adults

NCT05194358
View directory record Official record
Conditions
Cyanide Poisoning
Interventions
Stabilized Isoamyl Nitrite (SIAN)
Drug
Lead sponsor
Emergent BioSolutions
Industry
Eligibility
18 Years to 45 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Knoxville, Tennessee • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2025 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Phase 2 Interventional

Low-Fat Diet and/or Flaxseed in Preventing Prostate Cancer

NCT00049309
View directory record Official record
Conditions
Prostate Cancer
Interventions
dietary intervention, flaxseed
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
18 Years to 120 Years · Male only
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
3
States / cities
Ann Arbor, Michigan • Chapel Hill, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Nutrition for Chronic Daily Headache

NCT01157208
View directory record Official record
Conditions
Chronic Daily Headache
Interventions
Diet A, Diet B
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Role of the Gut Microbiota in Estrogen Metabolism and Dietary Flax as a Potential Modulator.

NCT03183102
View directory record Official record
Conditions
Menopause
Interventions
Flaxseed
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hallelujah Acres Omega 3 Fat Study

NCT01517685
View directory record Official record
Conditions
Omega 3 Fat Status
Interventions
Organic flax seed oil, fish oil
Dietary Supplement
Lead sponsor
Hallelujah Acres
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Zillah, Washington
Source: ClinicalTrials.gov public record
Updated Feb 18, 2016 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Phase 2 Interventional

Study of LYM-X-SORB™ to Improve Fatty Acid and Choline Status in Children With CF and PI

NCT00406536
View directory record Official record
Conditions
Cystic Fibrosis, Pancreatic Insufficiency
Interventions
Lym-X-Sorb powder, Placebo powder
Dietary Supplement
Lead sponsor
Avanti Polar Lipids, Inc.
Industry
Eligibility
6 Years to 17 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2013 · Synced Sep 2, 2026, 4:50 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

Polycystic Ovarian Syndrome: Impact of Flaxseed Supplementation

NCT00693082
View directory record Official record
Conditions
Polycystic Ovarian Syndrome
Interventions
flaxseed
Dietary Supplement
Lead sponsor
Duke University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 19, 2012 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Fats on Satiety and Energy Needs

NCT02496936
View directory record Official record
Conditions
Obesity
Interventions
SFA, MUFA, PUFA-LA, ALA, LCn3
Other
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
18 Years to 50 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Aug 3, 2022 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CCRC: Understanding the Effects of Omega-3 Fatty Acids Versus Lignans in Flaxseed on Metabolic and Inflammatory Markers Leading to Diabetes and Cardiovascular Disease

NCT00935922
View directory record Official record
Conditions
Body Weight, Lipids, Blood Glucose, Insulin
Interventions
Flaxseed
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
40 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2012 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Exploratory Investigation of a CBD Supplement's Impact on Sleep, Stress, and Focus

NCT05518019
View directory record Official record
Conditions
Anxiety, Fear, Stress, Low Mood, Sleep
Interventions
The Daily Supplement
Dietary Supplement
Lead sponsor
Prima CBD
Industry
Eligibility
18 Years to 60 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Aug 30, 2022 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Macrobiotic Diet and Flax Seed: Effects on Estrogens, Phytoestrogens, & Fibrinolytic Factors

NCT00010829
View directory record Official record
Conditions
Cardiovascular Diseases, Osteoporosis, Breast Cancer, Endometrial Cancer
Interventions
American Heart Association Step 1 diet, American Heart Association Step 2 diet + 10 g/day flax seed, Macrobiotic dietary intervention
Behavioral
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
50 Years to 72 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2006 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Placebo Controlled Double Masked Clinical Assessment Study of Essential Fatty Acid Supplement and Its Effect on Patients With Apparent Aqueous Deficient Dry Eye Syndrome

NCT00344721
View directory record Official record
Conditions
Dry Eye Syndrome
Interventions
Omega-3 fatty acid supplement, Placebo
Dietary Supplement
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 13, 2018 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Canola Oil Multi-Centre Intervention Trial II

NCT02029833
View directory record Official record
Conditions
Cardiovascular Disease, Diabetes, Metabolic Syndrome
Interventions
Regular Canola Oil, High Oleic Canola Oil, Western Type Diet - Common Dietary Oils
Other
Lead sponsor
University of Manitoba
Other
Eligibility
20 Years to 65 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 16, 2023 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Not applicable Interventional Results available

Flaxseed, Aromatase Inhibitors and Breast Tumor Characteristics

NCT00612560
View directory record Official record
Conditions
Breast Cancer
Interventions
Anastrozole, flaxseed, Placebo
Drug · Dietary Supplement
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 11, 2017 · Synced Sep 2, 2026, 4:50 PM EDT
Terminated Not applicable Interventional

Pilot Study of Dietary Modification of Appetite Set Point in Obesity

NCT00726271
View directory record Official record
Conditions
Obesity
Interventions
light olive oil, fish oil capsules, flax seed oil capsules
Dietary Supplement
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2021 · Synced Sep 2, 2026, 4:50 PM EDT
Terminated Phase 1 Interventional

Flaxseed Supplement in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Undergoing Chemotherapy and Radiation Therapy

NCT00955942
View directory record Official record
Conditions
Lung Cancer, Radiation Toxicity
Interventions
flaxseed, placebo
Dietary Supplement · Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years to 120 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 1, 2020 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Omega-3 Fatty Acids in Children and Adolescents With Bipolar Disorder

NCT00252486
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Flax oil
Drug
Lead sponsor
University of Rochester
Other
Eligibility
6 Years to 17 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 18, 2013 · Synced Sep 2, 2026, 4:50 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults

NCT07392723
View directory record Official record
Conditions
Cognitive Dysfunction, Alzheimer Disease, Blood-Brain Barrier, Apolipoprotein E, Deficiency or Defect of, Brain Aging, Fatty Acids, Omega-3
Interventions
Alpha-Linolenic Acid (2.6 g/day), Placebo Control Group
Drug · Dietary Supplement
Lead sponsor
Michal Schnaider Beeri, Ph.D.
Other
Eligibility
60 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Black Pepper on the Absorption of Nutrients in Vegetables

NCT03490955
View directory record Official record
Conditions
Black Pepper, Absorption, Carotenoid
Interventions
salad dressing (canola oil) and black pepper, salad dressing (canola oil), black pepper, salad, Salad dressing (olive oil) and black pepper, Salad dressing (corn oil) and black pepper, Salad dressing (sunflower oil) and black pepper, Salad dressing (flaxseed oil) and black pepper
Other
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
18 Years to 30 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Amherst, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Epithelial Healing and Visual Outcomes Using Omega-3 Therapy Before and After Photorefractive Keratectomy (PRK) Surgery

NCT01059019
View directory record Official record
Conditions
Refractive Error
Interventions
Omega-3 Fatty Acid Supplements
Dietary Supplement
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 28 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 20, 2013 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Canola Oil Multicentre Intervention Trial (COMIT)

NCT01233778
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Canola Oil, High Oleic Acid + DHA Canola Oil, High Oleic Acid Canola Oil, Flax Oil, Safflower Oil
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
20 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Sep 2, 2026, 4:50 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Flaxseed for the Treatment of Hot Flashes

NCT00275704
View directory record Official record
Conditions
Hot Flashes
Interventions
Flaxseed
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2005
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 9, 2011 · Synced Sep 2, 2026, 4:50 PM EDT