- Conditions
- Dentin Sensitivity
- Interventions
- Experimental Mouth Rinse 12027-033, Placebo Mouth Rinse
- Device · Other
- Lead sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 375 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014
- U.S. locations
- 2
- States / cities
- Fort Wayne, Indiana • Las Vegas, Nevada
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Showing 25–48
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- Conditions
- Dental Caries
- Interventions
- Test Dentifrice, Reference Dentifrice, Negative Control Dentifrice
- Drug
- Lead sponsor
- HALEON
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Gingivitis, Supragingival Plaque
- Interventions
- Brushing and Flossing of teeth, Brushing Only
- Device · Other
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Gingivitis
- Interventions
- Stannous fluoride, Sodium monofluorophosphate
- Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 98 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013
- U.S. locations
- 1
- States / cities
- Fort Wayne, Indiana
- Conditions
- Dental Plaque
- Interventions
- Experimental: U-shaped Power Toothbrush, Placebo Comparator: Soft Manual Toothbrush
- Device
- Lead sponsor
- Lander Enterprises, LLC
- Industry
- Eligibility
- 5 Years to 8 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Fort Wayne, Indiana
- Conditions
- Dental Plaque
- Interventions
- Fluoride, Triclosan
- Drug
- Lead sponsor
- Colgate Palmolive
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 44 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008
- U.S. locations
- 1
- States / cities
- Louisville, Kentucky
- Conditions
- Gingivitis
- Interventions
- 0.76% Sodium Monofluorophosphate Dentifrice, 0.454% Stannous Fluoride Dentifrice
- Drug
- Lead sponsor
- Procter and Gamble
- Industry
- Eligibility
- 25 Years to 65 Years
- Enrollment
- 135 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Fort Wayne, Indiana
- Conditions
- Plaque, Dental, Gingivitis
- Interventions
- Tapered bristles A, Tapered bristles B, End rounded bristles
- Device
- Lead sponsor
- Sunstar Americas
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Tooth Erosion
- Interventions
- Sodium fluoride, Sodium monoflurophosphate, Sterile water
- Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Oral Disease, Dental Caries
- Interventions
- Partnered intervention
- Behavioral
- Lead sponsor
- NYU College of Dentistry
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Dentin Sensitivity
- Interventions
- Stannous fluoride toothpaste, Regular fluoride toothpaste (Crest Cavity Protection)
- Drug
- Lead sponsor
- HALEON
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 115 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Melbourne, Florida
- Conditions
- Gingivitis
- Interventions
- Oscillating rotating power toothbrush
- Device
- Lead sponsor
- Marquette University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 55 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin
- Conditions
- Gingival Diseases
- Interventions
- Fluoride, Triclosan, fluoride
- Drug
- Lead sponsor
- Colgate Palmolive
- Industry
- Eligibility
- 18 Years to 76 Years
- Enrollment
- 105 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2008
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Dentinal Hypersensitivity
- Interventions
- Sensi-IP toothpaste, Sodium Fluoride Toothpaste
- Device
- Lead sponsor
- IR Scientific Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 46 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Cambridge, Massachusetts
- Conditions
- Gingivitis
- Interventions
- Marketed Toothpaste, Marketed Cavity Protection Toothpaste
- Drug
- Lead sponsor
- Procter and Gamble
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 90 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Las Vegas, Nevada
- Conditions
- Gingival Inflammation
- Interventions
- Stannous Fluoride Toothpaste (SnF)
- Drug
- Lead sponsor
- Colgate Palmolive
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Microbiome, Cytokines, Plaque, Gingivitis, Gingival Bleeding
- Interventions
- Distilled Water, Marketed Comparator 1, Marketed Comparator 2, Prototype Rinse 1, Prototype Rinse 2
- Other
- Lead sponsor
- Kenvue Brands LLC
- Industry
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 250 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Somerville, Massachusetts
- Conditions
- Dentin Hypersensitivity
- Interventions
- Triclosan, Silicon dioxide, fluoride, Triclosan, fluoride
- Drug
- Lead sponsor
- Colgate Palmolive
- Industry
- Eligibility
- 12 Years to 80 Years
- Enrollment
- 626 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008
- U.S. locations
- 1
- States / cities
- Cedar Knolls, New Jersey
- Conditions
- Gingivitis
- Interventions
- Stannous fluoride
- Drug
- Lead sponsor
- Procter and Gamble
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022
- U.S. locations
- 1
- States / cities
- Fort Wayne, Indiana
- Conditions
- Stain Removal Efficacy
- Interventions
- Whitening Test Dentifrice (Code 826), Control dentifrice (Code 378)
- Other
- Lead sponsor
- Church & Dwight Company, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 118 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Fort Wayne, Indiana
- Conditions
- Dentin Sensitivity, Oral Hygiene
- Interventions
- Test Dentifrice, Reference Dentifrice (Aquafresh Cavity Protection)
- Drug
- Lead sponsor
- HALEON
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 160 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Las Vegas, Nevada
- Conditions
- Dentin Sensitivity
- Interventions
- Control toothpaste containing Novamin® technology, Control toothpaste containing 1500 ppm fluoride as MFP, Test toothpaste with nano-HAP (high concentration), Test toothpaste with nano-HAP (low concentration), Test toothpaste with nano-HAP and (Potassium Nitrate) KNO3, Control toothpaste without nano-HAP, Test toothpaste with nano-HAP (medium concentration), Test cream with nano-HAP (higher concentration), Control cream without nano-HAP
- Drug
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 203 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Gingivits in Diabetics
- Interventions
- Listerine Cool Mint, 5% Hydroalcohol Mouth Rinse, Colgate Cavity Protection Toothpaste, Alcohol-Free Essential Oil Containing (AFEO) Mouth Rinse Lead Formula, Concept Curve Winter Series Toothbrush, Listerine Cool Mint Floss
- Other · Device
- Lead sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 154 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Fort Wayne, Indiana
- Conditions
- Caries
- Interventions
- 0 ppm F (placebo, negative control), 250 ppm F as NaF (dose-response control), 500 ppm F as NaF (dose-response control), 1100 ppm F as NaF (positive control)
- Drug
- Lead sponsor
- Domenick Zero
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 28 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana