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ClinicalTrials.gov public records Last synced Sep 30, 2026, 5:51 AM EDT

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Showing 25–48 of 3,715 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Focal treatment Clear all
Completed Not applicable Interventional Results available

Mindfulness Intervention to Study the Neurobiology of Depression

NCT01905267
View directory record Official record
Conditions
Depression
Interventions
Rumination-Focused Cognitive Behavior Therapy
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
12 Years to 18 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 30, 2018 · Synced Sep 30, 2026, 5:51 AM EDT
Recruiting Phase 1Phase 2 Interventional

Accelerated rTMS vs. Sham for Stroke Apathy

NCT07113067
View directory record Official record
Conditions
Apathy, Stroke, Stroke Sequelae, Stroke/Brain Attack, Stroke/ Cerebrovascular Accident (Ischemic or Hemorrhagic), Motivation, Abulia
Interventions
MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System (Active), MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System (Sham), Brainsight Neuronavigation System
Device · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
40 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 30, 2026, 5:51 AM EDT
Terminated Phase 4 Interventional Results available

A Study of Tamiflu (Oseltamivir) for Treatment of Influenza With a Focus on (H1N1) 2009 Flu Strain

NCT01032837
View directory record Official record
Conditions
Influenza
Interventions
Oseltamivir, Placebo
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
1 Year and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
100
States / cities
Tuscaloosa, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 91 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2012 · Synced Sep 30, 2026, 5:51 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Smoking Cessation Treatment for Adult Women

NCT01422239
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Tailored treatment, Standard Treatment
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 20, 2020 · Synced Sep 30, 2026, 5:51 AM EDT
Active, not recruiting Not applicable Interventional

HD-tDCS for Phonological Impairment in Aphasia

NCT06010030
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Targeted Transcranial Direct Current Stimulation, Speech Therapy
Device · Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2033
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Sep 30, 2026, 5:51 AM EDT
Active, not recruiting Not applicable Interventional Results available

The HistoSonics System for Treatment of Primary and Metastatic Liver Tumors Using Histotripsy

NCT04572633
View directory record Official record
Conditions
Liver Neoplasms, Hepatocellular Carcinoma, Liver Metastases
Interventions
HistoSonics System
Device
Lead sponsor
HistoSonics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
7
States / cities
Miami, Florida • Tampa, Florida • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Sep 30, 2026, 5:51 AM EDT
Active, not recruiting Phase 1 Interventional

Hypofractionated Accelerated Pelvic Nodal Radiotherapy (GCC 2048)

NCT04486755
View directory record Official record
Conditions
Prostate Cancer, Prostate Adenocarcinoma
Interventions
Hypofractionated Radiation Therapy
Radiation
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older · Male only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 30, 2026, 5:51 AM EDT
Completed Not applicable Interventional

Pilot Sleep Intervention to Improve Diabetes Management in School-Aged Children

NCT03397147
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Sleep Coach Jr.
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
5 Years to 9 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Sep 30, 2026, 5:51 AM EDT
Recruiting Not applicable Interventional

Low-Intensity Focused Ultrasound and the Complex Patient

NCT06297200
View directory record Official record
Conditions
Opioid Use Disorder, Chronic Pain, Anxiety Disorder
Interventions
Low-Intensity Focused Ultrasound, Low-Intensity Focused Ultrasound - sham
Device
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 30, 2026, 5:51 AM EDT
Active, not recruiting Not applicable Interventional

Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care

NCT04601064
View directory record Official record
Conditions
HIV Infections, Substance Use Disorders, Mental Health Disorder, Addiction, Opioid Use, Drug Use
Interventions
Collaborative Care Model
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
405 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Sep 30, 2026, 5:51 AM EDT
Completed Not applicable Interventional

Effects of Palliative Care on Quality of Life and Symptom Control in Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery

NCT00823732
View directory record Official record
Conditions
Lung Cancer
Interventions
educational intervention, medical chart review, questionnaire administration, end-of-life treatment/management, psychosocial assessment and care, quality-of-life assessment, management of therapy complications, assessment of therapy complications
Other · Procedure
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Duarte, California
Source: ClinicalTrials.gov public record
Updated Nov 6, 2015 · Synced Sep 30, 2026, 5:51 AM EDT
Completed Not applicable Interventional

Juvenile Justice Girls Randomized Control Trial: Young Adult Follow-up

NCT01341626
View directory record Official record
Conditions
Delinquency, Drug Use
Interventions
Treatment Foster Care (TFCO), Group Care
Behavioral
Lead sponsor
Oregon Social Learning Center
Other
Eligibility
13 Years to 18 Years · Female only
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2016
U.S. locations
2
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 11, 2022 · Synced Sep 30, 2026, 5:51 AM EDT
Completed Phase 1 Interventional

Effectiveness of Cognitive Therapy for Suicide Attempters With Drug Dependence Disorder

NCT00218725
View directory record Official record
Conditions
Suicide, Attempted, Substance-Related Disorders
Interventions
Cognitive Therapy, Enriched Care
Behavioral · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 29, 2015 · Synced Sep 30, 2026, 5:51 AM EDT
Completed Phase 2 Interventional

Radiofrequency Interstitial Tissue Ablation in Treating Patients With Localized Renal Cell Carcinoma (Kidney Cancer)

NCT00019955
View directory record Official record
Conditions
Kidney Cancer
Interventions
laparoscopic surgery, radiofrequency ablation, thermal ablation therapy
Procedure
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 29, 2015 · Synced Sep 30, 2026, 5:51 AM EDT
Terminated Phase 3 Interventional Results available

Evaluation of the CR Plug (Allograft) for the Treatment of a Cartilage Injury in the Knee.

NCT00793104
View directory record Official record
Conditions
Knee Injury
Interventions
Placement of allograft CR Plug in primary injury site
Procedure
Lead sponsor
RTI Surgical
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
3
States / cities
Los Angeles, California • Denver, Colorado • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 25, 2013 · Synced Sep 30, 2026, 5:51 AM EDT
Completed Not applicable Interventional Results available

A Randomized Controlled Trial of In-Home Tele-Behavioral Health Care Utilizing Behavioral Activation for Depression

NCT01599585
View directory record Official record
Conditions
Depression
Interventions
Behavioral Activation
Behavioral
Lead sponsor
National Center for Telehealth and Technology
Federal
Eligibility
18 Years to 65 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Portland, Oregon • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jun 16, 2017 · Synced Sep 30, 2026, 5:51 AM EDT
Completed Phase 2 Interventional

Gemcitabine Plus Docetaxel in Treating Patients With Unresectable or Metastatic Liver Cancer

NCT00006010
View directory record Official record
Conditions
Liver Cancer
Interventions
docetaxel, gemcitabine hydrochloride
Drug
Lead sponsor
Alliance for Clinical Trials in Oncology
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2008
U.S. locations
16
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Atlanta, Georgia + 13 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Sep 30, 2026, 5:51 AM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Targeting Minority Stressors to Improve Eating Disorder Symptoms in Sexual Minority Individuals With Eating Disorders

NCT06565637
View directory record Official record
Conditions
Eating Disorders, Sexual Minorities
Interventions
Promoting Resilience to Improve Disordered Eating
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Auburn, Alabama • San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Sep 30, 2026, 5:51 AM EDT
Completed Phase 1 Interventional

Effect of Family-Based Prevention on Children of Depressed Parents

NCT00183365
View directory record Official record
Conditions
Depression
Interventions
Parent Skills Training, Protecting Families Program (PFP)
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
9 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 9, 2026 · Synced Sep 30, 2026, 5:51 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Step-up to Quit: Using Low-to-moderate Intensity Exercise for Reducing Smoking Cue Reactivity Among Low-income Smokers

NCT02220465
View directory record Official record
Conditions
Sedentary Lifestyle, Cigarette Smoking
Interventions
PA+ Smoking Cessation (LMPA), Standard Care Smoking Counseling (SCC)
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 59 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2014 · Synced Sep 30, 2026, 5:51 AM EDT
Completed Not applicable Interventional

Peer-Administered Asthma Self-Management Intervention in Urban Middle Schools

NCT03446365
View directory record Official record
Conditions
Asthma
Interventions
ASMAS, Asthma education plus child health
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
11 Years to 14 Years
Enrollment
243 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 27, 2024 · Synced Sep 30, 2026, 5:51 AM EDT
Not listed Not applicable Interventional

An ACT-enhanced Weight Management and Fitness Program for Navy Personnel

NCT03029507
View directory record Official record
Conditions
Obesity, Overweight
Interventions
ACT Enhanced ShipShape, Standard ShipShape (SS)
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years to 69 Years
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 19, 2022 · Synced Sep 30, 2026, 5:51 AM EDT
Active, not recruiting Not applicable Interventional

Brain, Emotions, and Mind-Wandering

NCT05345392
View directory record Official record
Conditions
Mood Disorders
Interventions
Mindfulness-Based Intervention (MBI), Health and Wellness Intervention (HWI)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
11 Years to 14 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 30, 2026, 5:51 AM EDT
Recruiting Phase 2 Interventional

Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer

NCT05312671
View directory record Official record
Conditions
Small Cell Neuroendocrine Carcinoma of Bladder, Bladder Cancer, Urothelial Carcinoma Bladder
Interventions
Atezolizumab, Carboplatin, Cisplatin, Etoposide, Cystectomy
Drug · Procedure
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 30, 2026, 5:51 AM EDT