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ClinicalTrials.gov public records Last synced Oct 6, 2026, 9:41 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 3,720 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Focal treatment Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Telehealth Intervention for Autism Spectrum Disorder

NCT04832152
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
OT4ASD
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
4 Years to 12 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced Oct 6, 2026, 9:41 PM EDT
Completed Not applicable Interventional

Cognitive Behavioral Therapy for Adolescents With Bulimia Nervosa and Higher Weight (Online Treatment Study)

NCT05770947
View directory record Official record
Conditions
Bulimia Nervosa, Overweight or Obesity
Interventions
Cognitive Behavioral Therapy, Mindfulness
Behavioral
Lead sponsor
Yale University
Other
Eligibility
12 Years to 19 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 6, 2026, 9:41 PM EDT
Terminated Not applicable Interventional

Radiofrequency-Based Debridement vs. Mechanical Debridement for the Treatment of Articular Cartilage Lesions

NCT03678948
View directory record Official record
Conditions
Articular Cartilage Disorder of Knee
Interventions
Radiofrequency-Based Debridement, Mechanical Debridement
Device
Lead sponsor
Christopher Kaeding
Other
Eligibility
18 Years to 50 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 30, 2021 · Synced Oct 6, 2026, 9:41 PM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

CyberKnife Radiosurgery for Localized Prostatic Carcinoma

NCT01045148
View directory record Official record
Conditions
Prostate Cancer
Interventions
CyberKnife Radiosurgery
Radiation
Lead sponsor
CyberKnife Centers of San Diego
Other
Eligibility
18 Years and older · Male only
Enrollment
258 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2006
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Oct 6, 2026, 9:41 PM EDT
Completed Phase 2 Interventional

Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors

NCT00005955
View directory record Official record
Conditions
Brain and Central Nervous System Tumors, Neuroblastoma
Interventions
temozolomide
Drug
Lead sponsor
Duke University
Other
Eligibility
4 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 20, 2013 · Synced Oct 6, 2026, 9:41 PM EDT
Recruiting Not applicable Interventional

PILOT for The Precision Exercise Regimen for Cancer Care (PERCC) Study

NCT06945484
View directory record Official record
Conditions
NSCLC Stage II, NSCLC, Stage III
Interventions
Precision Exercise Regimen for Cancer Care (PERCC)
Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
Galveston, Texas • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 6, 2026, 9:41 PM EDT
Completed Not applicable Interventional

Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption

NCT03551249
View directory record Official record
Conditions
Glioma, Glioblastoma
Interventions
Focused ultrasound (FUS)
Device
Lead sponsor
InSightec
Industry
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
4
States / cities
Baltimore, Maryland • Boston, Massachusetts • Charlottesville, Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 6, 2026, 9:41 PM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Therapeutic Strategies to Reduce Endothelial Ischemia-reperfusion Injury

NCT06825143
View directory record Official record
Conditions
Metabolic Syndrome, Vascular Injury, Ischemic Preconditioning, Endothelial Function (reactive Hyperemia), Endothelial Dysfunction
Interventions
Ischemic preconditioning, Intravenous lactate infusion, No ischemic preconditioning (control), Normal Saline Infusion (Placebo), Ischemic preconditioning and intravenous lactate
Procedure · Drug · Combination Product
Lead sponsor
Gary Van Guilder
Other
Eligibility
18 Years to 65 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Gunnison, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 13, 2025 · Synced Oct 6, 2026, 9:41 PM EDT
Completed Not applicable Interventional

Facial Affect Sensitivity Training for Young Children With Callous-unemotional Traits

NCT04159168
View directory record Official record
Conditions
Affective Symptoms, Empathy
Interventions
Facial Affect Sensitivity Training (FAST), Implicit Gaze Training task (Active control condition)
Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
6 Years to 11 Years
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 6, 2026, 9:41 PM EDT
Completed Phase 2 Interventional Results available

Chemoembolization Versus Radioembolization in Treating Patients With Liver Cancer That Cannot Be Treated With Radiofrequency Ablation Or Surgery

NCT00956930
View directory record Official record
Conditions
Liver Cancer
Interventions
yttrium Y 90 glass microspheres, Doxorubicin
Radiation · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 120 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced Oct 6, 2026, 9:41 PM EDT
Suspended Phase 3 Interventional

High Intensity Focused Ultrasound (HIFU) Ablation System Study

NCT00392106
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
propafenone, flecainide, dofetilide, sotolol, Pulmonary vein ablation, Amiodarone
Drug · Device
Lead sponsor
ProRhythm, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
20
States / cities
Fullerton, California • Los Angeles, California • Atlanta, Georgia + 16 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2008 · Synced Oct 6, 2026, 9:41 PM EDT
Recruiting Not applicable Interventional

Trial of Differential Margins in Single Isocenter Radiosurgery of Brain Metastases

NCT06857006
View directory record Official record
Conditions
Brain Metastases
Interventions
brain metastases radiosurgery
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 6, 2026, 9:41 PM EDT
Completed Not applicable Interventional

Multi-domain Online Therapeutic Investigation Of Neurocognition (MOTION)

NCT05217849
View directory record Official record
Conditions
Mild Cognitive Impairment, Subjective Memory Decline
Interventions
Tai Chi, Preventing Loss of Independence through Exercise (PLIE), Health and Wellness Education
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
55 Years and older
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 6, 2026, 9:41 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Hearing Healthcare Assessment in Rural Communities

NCT05786794
View directory record Official record
Conditions
Hearing Loss, Adult-Onset, Hearing Loss, Age-Related
Interventions
Patient Navigation Program for Hearing Health Care
Behavioral
Lead sponsor
Matthew Bush, MD
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
9
States / cities
Campbellsville, Kentucky • Campton, Kentucky • Elkton, Kentucky + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 6, 2026, 9:41 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Radiation and Androgen Ablation for Prostate Cancer

NCT01517451
View directory record Official record
Conditions
Adenocarcinoma of the Prostate
Interventions
Radiation Therapy, Androgen Deprivation Therapy (ADT)
Radiation · Drug
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years to 100 Years · Male only
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2025
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 6, 2026, 9:41 PM EDT
Terminated Phase 1Phase 2 Interventional Results available

Localized Radiation Therapy or Recombinant Interferon Beta and Avelumab With or Without Cellular Adoptive Immunotherapy in Treating Patients With Metastatic Merkel Cell Carcinoma

NCT02584829
View directory record Official record
Conditions
Merkel Cell Polyomavirus Infection, Stage IV Merkel Cell Carcinoma AJCC v7
Interventions
Avelumab, Laboratory Biomarker Analysis, MCPyV TAg-specific Polyclonal Autologous CD8-positive T Cells, Radiation Therapy, Recombinant Interferon Beta
Drug · Other · Biological + 1 more
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Oct 6, 2026, 9:41 PM EDT
Completed Not applicable Interventional Results available

Theranostics of Radiolabeled Somatostatin Antagonists 68Ga-DOTA-JR11 and 177Lu-DOTA-JR11 in Patients With Neuroendocrine Tumors

NCT02609737
View directory record Official record
Conditions
Neuroendocrine Tumors
Interventions
PET/CT Imaging, 68Ga-DOTA-JR11, 177Lu-DOTA-JR11
Device · Radiation
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 1, 2022 · Synced Oct 6, 2026, 9:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Sedentary Time in Chronic Low Back Pain: Sedentary Intervention Using Motivational Interviewing and Technology

NCT04257539
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
Intervention to Reduce Sedentary Time
Behavioral
Lead sponsor
Iowa State University
Other
Eligibility
25 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Ames, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 10, 2020 · Synced Oct 6, 2026, 9:41 PM EDT
Completed Not applicable Interventional Results available

Randomized Evaluation of Atrial Fibrillation Treatment With Focal Impulse and Rotor Modulation Guided Procedures

NCT02274857
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
Standard PVI Ablation, FIRM-Guided Procedure and PVI
Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 80 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
10
States / cities
Phoenix, Arizona • Newport Beach, California • Maywood, Illinois + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2020 · Synced Oct 6, 2026, 9:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ulthera® System for Treating Axillary Hyperhidrosis

NCT02286765
View directory record Official record
Conditions
Primary Axillary Hyperhidrosis
Interventions
Ulthera System treatment
Device
Lead sponsor
Ulthera, Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 14, 2017 · Synced Oct 6, 2026, 9:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Novel Treatment of Emotional Dysfunction in Post Traumatic Stress Disorder (PTSD)

NCT01391832
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Processing Therapy, Repetitive Transcranial Magnet Stimulation (rTMS)
Device · Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 60 Years
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2024 · Synced Oct 6, 2026, 9:41 PM EDT
Recruiting Not applicable Interventional

Post Approval Study for Treatment of Drug-resistant Adult and Pediatric Primary FSGS Using the LIPOSORBER® LA-15 System

NCT04065438
View directory record Official record
Conditions
Focal Segmental Glomerulosclerosis
Interventions
LIPOSORBER® LA-15
Device
Lead sponsor
Kaneka Medical America LLC
Industry
Eligibility
Up to 75 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
10
States / cities
Loma Linda, California • Wilmington, Delaware • Grand Rapids, Michigan + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 6, 2026, 9:41 PM EDT
Completed Phase 2 Interventional

DX-8951f in Treating Patients With Biliary Cancer

NCT00005938
View directory record Official record
Conditions
Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer
Interventions
exatecan mesylate
Drug
Lead sponsor
Daiichi Sankyo
Industry
Eligibility
16 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
5
States / cities
Denver, Colorado • New York, New York • Dallas, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated May 16, 2012 · Synced Oct 6, 2026, 9:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Psychosocial Treatment for Women With Depression and Pain

NCT00895999
View directory record Official record
Conditions
Pelvic Pain, Depression
Interventions
Interpersonal Therapy for Pain (IPT-P), Enhanced Support and Connection to Counseling
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 14, 2014 · Synced Oct 6, 2026, 9:41 PM EDT