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Showing 25–48 of 78 matching trials from the live ClinicalTrials.gov search.
Not listed Not applicable Interventional Accepts healthy volunteers

Investigating Auto Adjusting Dynamic AFO

NCT04623853
Conditions
Lower Limb; Fusion, Congenital, Lower Limb Fracture, Ankle Foot Injury
Interventions
Variable Stiffness AFO
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Active, not recruiting Not applicable Interventional

C-Brace II Spinal Cord Injury

NCT03930056
Conditions
Spinal Cord Injury
Interventions
C-Brace II, Traditional Care KAFO intervention
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Assistive ExoSkeletons to Enable Wearable Rehabilitation Robotics

NCT03717233
Conditions
Diabetic Foot Ulcer, Diabetic Foot Ulcer Associated With Type II Diabetes Mellitus
Interventions
Exoskeleton
Device
Lead sponsor
Results Group LLC
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Los Angeles, California • New Haven, Connecticut
Conditions
Ankle Injuries, Foot Injury
Interventions
Monster Screw System
Device
Lead sponsor
Paragon 28
Industry
Eligibility
Not listed
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Jackson, Michigan
Conditions
Plantar Fasciitis, Chronic
Interventions
minimal shoes and foot strengthening and flexibility exercises, Supportive Footwear, foot orthotic device and foot flexibility exercises
Device
Lead sponsor
University of South Florida
Other
Eligibility
50 Years to 70 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Peripheral Artery Disease
Interventions
intermittent pneumatic compression, exercise, Sham device, Health Education
Device · Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
55 Years and older
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
4
States / cities
Chicago, Illinois • Detroit, Michigan • Minneapolis, Minnesota
Terminated No phase listed Observational Accepts healthy volunteers Results available

Improving the Detection, Classification and Treatment of Misaligned Arthritic Ankles

NCT03440008
Conditions
Ankle Osteoarthritis
Interventions
Dynamic 3D bone motion capture, wedged insole
Other · Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 70 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Results available

Ankle Foot Orthosis Comparative Effect

NCT03901053
Conditions
Foot Injuries and Disorders
Interventions
Reaktiv AFO, PhatBrace AFO
Device
Lead sponsor
Jason Wilken
Other
Eligibility
18 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
3
States / cities
Iowa City, Iowa • Bethesda, Maryland • Minneapolis, Minnesota
Conditions
Amputation
Interventions
Kinnex, Pacifica LP
Device
Lead sponsor
Ability Prosthetics and Orthotics, Inc.
Industry
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
3
States / cities
Hagerstown, Maryland • Charlotte, North Carolina • York, Pennsylvania
Recruiting Not applicable Interventional Accepts healthy volunteers

Foot Strengthening to Improve Balance and Gait in Older Adults

NCT07384754
Conditions
Minimalist Footwear, Traditional Foot Exercise Program, Foot Strengthening Device (ToePro), Control Condition
Interventions
Minimalist footwear, Foot strengthening exercises, ToePro foot strengthening device
Device · Behavioral
Lead sponsor
Indiana University
Other
Eligibility
45 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress

NCT04562896
Conditions
Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
Interventions
Custom Carbon Fiber Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Diabetic Foot Ulcer
Interventions
PEP (Purified Exosome Product) / TISSEEL
Biological
Lead sponsor
Rion Inc.
Industry
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Blue Ash, Ohio
Conditions
Cerebral Palsy
Interventions
Biomotum Spark: Robotic ankle assistance, Biomotum Spark: Robotic ankle resistance, Standard gait training, Ankle foot orthosis, Standard physical therapy, Standard walking
Device · Other
Lead sponsor
Northern Arizona University
Other
Eligibility
8 Years to 21 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Plantar Fasciosis, Achilles Tendinosis
Interventions
TOPAZ MicroDebrider
Device
Lead sponsor
ArthroCare Corporation
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2007
U.S. locations
3
States / cities
Mesa, Arizona • Santa Monica, California • Oakwood, Georgia
Not yet recruiting Not applicable Interventional

Motus Nova Foot Device for Patients With Hemiplegia

NCT07754773
Conditions
Hemiplegia, Cerebral Palsy, Hemiplegic Cerebral Palsy
Interventions
Motus Nova Foot
Device
Lead sponsor
MultiCare Health System Research Institute
Other
Eligibility
12 Years to 20 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Puyallup, Washington
Conditions
Sarcoma, Bone, Sarcoma, Soft Tissue, Gait Disorder
Interventions
Lab based 3D Gait Assessment, Wearable Inertial Sensors (In Lab and Remote), Functional Testing & Patient Reported Outcomes, Remote Wearable Sensor Assessment
Diagnostic Test · Device · Other
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
5 Years to 20 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
Memphis, Tennessee
Recruiting Not applicable Interventional

Nomad P-KAFO Study

NCT05644522
Conditions
Cerebrovascular Accident, Post-polio Syndrome, Spinal Cord Injuries, Multiple Sclerosis, Muscular Dystrophy, Paralysis
Interventions
Indego Nomad® Powered Knee-Ankle-Foot Orthosis (P-KAFO) (Parker Hannifin Corp., Cleveland, OH)
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 89 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Terminated No phase listed Observational Accepts healthy volunteers Results available

SCANREP: Reliability of 3D Lower Limb Scanning

NCT04032041
Conditions
Foot Injuries and Disorders
Interventions
Structure Sensor, Caliper
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Ankle Foot Orthosis (AFO), Stroke Patients, Post-Stroke Hemiparesis
Interventions
Pre-fabricated (PF) ankle-foot orthosis (AFO), Carbon-strut (CS) ankle-foot orthosis (AFO), Multifunctional articulating (MA) ankle-foot orthosis (AFO)
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
Downey, California • Jacksonville, Florida • Charleston, South Carolina + 1 more
Conditions
Multiple Sclerosis
Interventions
Ankle-bot, Conventional focused ankle therapy
Device · Other
Lead sponsor
Mount Sinai Rehabilitation Hospital
Other
Eligibility
25 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Hartford, Connecticut
Terminated No phase listed Observational Accepts healthy volunteers Results available

Wright Foot & Ankle Post-Market Observational Study

NCT04118894
Conditions
Arthritis, Rheumatoid Arthritis, Fracture, Trauma Injury, Fusion of Joint
Interventions
Foot and Ankle Devices
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Hamilton, New Jersey • Charlotte, North Carolina
Conditions
Diabetic Foot Ulcer, Surgical Wound
Interventions
Natrox® Oxygen Wound Therapy
Device
Lead sponsor
Inotec AMD Limited
Industry
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
19
States / cities
Los Angeles, California • Miami, Florida • Miami Lakes, Florida + 15 more
Conditions
Peripheral Neuropathies, Peripheral Neuropathy Due to Chemotherapy, Peripheral Neuropathy With Type 2 Diabetes, Balance Control in Elderly, Gait Disorders
Interventions
Walkasins, Fall Prevention Training
Device · Other
Lead sponsor
RxFunction Inc.
Industry
Eligibility
55 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Mesa, Arizona • Boston, Massachusetts • Saint Paul, Minnesota + 3 more
Conditions
Peripheral Arterial Disease
Interventions
Intermittent pneumatic leg compressions, Sham
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana