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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Fractional Laser Clear all
Completed No phase listed Observational Results available

Laser Therapy for Treatment of Urogenital Symptoms in Women

NCT03681678
View directory record Official record
Conditions
Genitourinary System; Disorder, Female, Burning Vagina, Dyspareunia, Irritation; Vagina, Menopause Related Conditions, Urinary Incontinence, Urinary Bladder, Overactive, Urinary Tract Infections, Stress Urinary Incontinence
Interventions
fCO2 Laser Therapy Group
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 25, 2026, 5:57 AM EDT
Completed Not applicable Interventional

Randomized, Controlled Trial With Hybrid Fractional Laser

NCT03647189
View directory record Official record
Conditions
Vaginal Atrophy, Sexual Dysfunction, Vaginal Dryness, Dyspareunia
Interventions
Hybrid Fractional Laser
Device
Lead sponsor
Sciton
Industry
Eligibility
40 Years to 70 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 17, 2021 · Synced Sep 25, 2026, 5:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Tattoo Removal: a Side-by-side Comparison in the Search for One Treatment Tattoo Removal

NCT01624688
View directory record Official record
Conditions
Tattoo, Tattoo Removal
Interventions
Tattoo Removal
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Sep 25, 2026, 5:57 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Compression and CO2 Laser for Leg Wounds

NCT04198454
View directory record Official record
Conditions
Wound Healing
Interventions
Compression bandages, Standard wound dressings, Fractional ablative carbon dioxide laser
Other · Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 25, 2026, 5:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation

NCT06366503
View directory record Official record
Conditions
Photoaging, Wrinkle, Skin Laxity
Interventions
Fractional Ablative CO2 Laser, Facial Cleanser, Facial Moisturizer, Sunscreen, Basic Ointment
Procedure · Other
Lead sponsor
Revision Skincare
Industry
Eligibility
35 Years to 65 Years · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Blue Ash, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 2, 2025 · Synced Sep 25, 2026, 5:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

LASER Pilot Project

NCT05966636
View directory record Official record
Conditions
Acquired Absence of Lower Limb, Scar Condition and Fibrosis of the Skin
Interventions
Fractional CO2 Laser Ablative Resurfacing
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Miami, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Sep 25, 2026, 5:57 AM EDT
Terminated Not applicable Interventional Results available

Ablative Fractional Laser for Sclerotic GVHD-Associated Joint Contractures

NCT02881047
View directory record Official record
Conditions
Subjects With Severe, Refractory Sclerotic Skin Changes
Interventions
CO2 Laser, Ultrasound, Skin Biopsy
Device · Radiation · Diagnostic Test
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 15, 2020 · Synced Sep 25, 2026, 5:57 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

1550nm Non-ablative Fractional Vs 1927nm Thulium Fractional Laser for the Treatment of Female Pattern Hair Loss

NCT06926023
View directory record Official record
Conditions
Female Pattern Baldness
Interventions
1550nm non-ablative fractional laser, 1927 thulium fractional laser
Device
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
35 Years to 65 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Sep 25, 2026, 5:57 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Fractional CO2 Laser for the Treatment of Lichen Planus Pigmentosus

NCT05170308
View directory record Official record
Conditions
Lichen Planus Pigmentosus
Interventions
CO2 fractional laser
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 1, 2022 · Synced Sep 25, 2026, 5:57 AM EDT
Not listed Not applicable Interventional

Histological Study of the Effects of a 2910 nm Fiber Laser Technology

NCT06317766
View directory record Official record
Conditions
Skin Laxity
Interventions
2910 nm Fiber Laser Treatment; Pre-Clinical Histology Evaluation, 2910 nm Fiber Laser Treatment; Part 2 Histology Evaluation
Device
Lead sponsor
FA Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Sep 25, 2026, 5:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fractional Ablative Radiofrequency for the Treatment of Acne Scars and Wrinkles

NCT01645345
View directory record Official record
Conditions
Wrinkles, Acne Scars
Interventions
Alma Lasers Accent RF Pixel handpiece
Device
Lead sponsor
Alma Lasers Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
3
States / cities
Glenview, Illinois • Las Vegas, Nevada • Bryn Mawr, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 23, 2020 · Synced Sep 25, 2026, 5:57 AM EDT
Recruiting Phase 4 Interventional

Remimazolam vs Propofol in Laser Burn Cases

NCT07213544
View directory record Official record
Conditions
Burn Scar, Hypertrophic Scarring, Procedural Sedation
Interventions
Remimazolam besylate, Propofol
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Sep 25, 2026, 5:57 AM EDT
Terminated No phase listed Observational

Potential Benefits of Laser Treatment on Skin Blood Flow and Sweating in Burn Survivors

NCT04947449
View directory record Official record
Conditions
Burn Injury
Interventions
fractional CO2 laser
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Timeline
2021 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Sep 25, 2026, 5:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Lasers in the Treatment of Scars

NCT02988622
View directory record Official record
Conditions
Scar
Interventions
Fraxel Laser, CO2 Laser
Device
Lead sponsor
Marta Hemmingson-Van Beek
Other
Eligibility
18 Years to 120 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Sep 25, 2026, 5:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Fractional Carbon Dioxide (CO2) Laser Treatment Prior to Wound Closure

NCT00969475
View directory record Official record
Conditions
Scars
Interventions
Lumenis fractional carbon dioxide laser
Device
Lead sponsor
Moy-Fincher Medical Group
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 14, 2009 · Synced Sep 25, 2026, 5:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Histologic Evaluation of Tissue Following Lutronic System Exposure

NCT04207047
View directory record Official record
Conditions
Abdominoplasty
Interventions
Genius, eC02, PicoPlus, LaseMD, LaseMD Flex
Device
Lead sponsor
CynosureLutronic
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Billerica, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 19, 2019 · Synced Sep 25, 2026, 5:57 AM EDT
Completed Not applicable Interventional Results available

PicoWay™ 730 Resolve Fusion for Benign Pigmented Lesions and Wrinkles

NCT03774849
View directory record Official record
Conditions
Benign Pigmented Lesions, Facial Wrinkles
Interventions
PicoWay™ 532nm fractional handpiece, PicoWay™ 730nm wavelength, PicoWay™ 1064nm fractional handpiece
Device
Lead sponsor
Candela Corporation
Industry
Eligibility
21 Years to 80 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Wayland, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Sep 25, 2026, 5:57 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Gene Expression During Surgical Scar Remodeling by Fractional Photothermolysis

NCT01858038
View directory record Official record
Conditions
Hypertrophic Scars
Interventions
Fraxel Repair - Fractional Laser treatment
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2019 · Synced Sep 25, 2026, 5:57 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Fractional Photothermolysis for Hair Follicle Induction

NCT03382184
View directory record Official record
Conditions
Alopecia
Interventions
Fraxel Dual laser, Halo laser
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 90 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Sep 25, 2026, 5:57 AM EDT
Terminated Not applicable Interventional Results available

Laser Treatment for Vulvar Lichen Sclerosus

NCT04134494
View directory record Official record
Conditions
Vulvar Lichen Sclerosus
Interventions
Ablative Fractional 2940 nm Laser
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Sep 25, 2026, 5:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vaginal Changes After CO2 Laser

NCT06691178
View directory record Official record
Conditions
Genitourinary Syndrome of Menopause
Interventions
Optical coherence tomography (OCT)
Diagnostic Test
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 25, 2026, 5:57 AM EDT
Withdrawn Not applicable Interventional

A Single-Blind, Randomized Study to Compare fCO2 Laser Therapy Versus Sham for Treatment of SUI in Women

NCT04253067
View directory record Official record
Conditions
Stress Urinary Incontinence, Urinary Incontinence
Interventions
Active fCO2 laser treatment, Sham fCO2 laser treatment
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years to 75 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Sep 25, 2026, 5:57 AM EDT
Terminated Not applicable Interventional

Scar Prevention Using Fractional Carbon Dioxide Laser Treatment

NCT01826942
View directory record Official record
Conditions
Scar Prevention
Interventions
Lumenis UltraPulse single fractional CO2 laser treatment thin skin, Single fractional CO2 treatment at surgical area closure procedure on thick skin
Device
Lead sponsor
Lumenis Be Ltd.
Industry
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2014 · Synced Sep 25, 2026, 5:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Pilot Study of the Effect of Laser on Reversing Chronic Radiation Injury

NCT01910818
View directory record Official record
Conditions
Chronic Radiation Dermatitis
Interventions
Fractional CO2 laser treatment, No treatment
Device · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Sep 25, 2026, 5:57 AM EDT