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ClinicalTrials.gov public records Last synced Sep 9, 2026, 12:47 AM EDT

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Showing 1–24 of 46 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Fractional ablative laser Clear all
Completed Early Phase 1 Interventional Accepts healthy volunteers

Fractional Laser vs. Ultrasound for Periorbital Wrinkles

NCT01529983
View directory record Official record
Conditions
Wrinkles
Interventions
Laser treatment, High-intensity focused ultrasound
Procedure · Device
Lead sponsor
Northwestern University
Other
Eligibility
35 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 9, 2026, 12:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing Tattoo Removal: a Side-by-side Comparison in the Search for One Treatment Tattoo Removal

NCT01624688
View directory record Official record
Conditions
Tattoo, Tattoo Removal
Interventions
Tattoo Removal
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Sep 9, 2026, 12:47 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy of a 2,910 nm Fractional Ablative Fiber Laser (UltraClear®) for Improvements of Skin Laxity and Lifting of the Lower Face, Submental, and Neck Treatment Areas

NCT07759817
View directory record Official record
Conditions
Skin Laxity (Submental and Neck), Skin Lifting and Tightening
Interventions
2910 nm fiber laser (UltraClear®)
Device
Lead sponsor
FA Corporation
Industry
Eligibility
35 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Prospect, Kentucky • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 9, 2026, 12:47 AM EDT
Active, not recruiting Not applicable Interventional

Safety and Efficacy of 2910 nm Fiber Laser Resurfacing and Laser-Coring

NCT07254884
View directory record Official record
Conditions
Rhytids, Skin Laxity
Interventions
2,910 nm mid-infrared erbium-doped fluoride fiber glass laser (UltraClear, Acclaro Medical)
Device
Lead sponsor
FA Corporation
Industry
Eligibility
45 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Edina, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 9, 2026, 12:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Non-Ablative Laser for Treatment of Direct Brow Lift Scars

NCT02032641
View directory record Official record
Conditions
Scar
Interventions
Laser treatment
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
2
States / cities
Miami, Florida • Plantation, Florida
Source: ClinicalTrials.gov public record
Updated Jan 26, 2017 · Synced Sep 9, 2026, 12:47 AM EDT
Withdrawn Not applicable Interventional

Acne Scarring in Skin of Color: Laser vs Microneedling

NCT03395678
View directory record Official record
Conditions
Acne Vulgaris, Scar
Interventions
Microneedling, Fractional non-ablative 1,540nm laser
Device
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 12, 2019 · Synced Sep 9, 2026, 12:47 AM EDT
Terminated Not applicable Interventional Results available

Laser Treatment for Vulvar Lichen Sclerosus

NCT04134494
View directory record Official record
Conditions
Vulvar Lichen Sclerosus
Interventions
Ablative Fractional 2940 nm Laser
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 4, 2024 · Synced Sep 9, 2026, 12:47 AM EDT
Recruiting Phase 1Phase 2 Interventional

Treating Basal and Squamous Cell Carcinomas With Fractional Laser and Tirbanibulin Ointment

NCT07010692
View directory record Official record
Conditions
Keratinocyte Carcinoma, Basal Cell Carcinomas, Squamous Cell Carcinoma, Skin Cancer
Interventions
Tirbanibulin ointment 1%, non-ablative fractional laser
Drug · Device
Lead sponsor
Bruce Robinson, MD
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 9, 2026, 12:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Fractionated 1927-nm Non Ablative Thulium Laser in Treating Post Inflammatory Hyperpigmentation

NCT06149780
View directory record Official record
Conditions
Healthy
Interventions
Patients treated with laser
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Sep 9, 2026, 12:47 AM EDT
Not yet recruiting Phase 2Phase 3 Interventional

Skin Care Regimen for Improving Photoaging Signs on the Face

NCT06603857
View directory record Official record
Conditions
Improve Photoaging Signs
Interventions
CE Ferulic, Sham Comparator, 1927nm (Clear and Brilliant Perméa®)
Drug · Device
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
30 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 9, 2026, 12:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Fractional Ablative Laser Treatment for Skin Conditions

NCT05750901
View directory record Official record
Conditions
Skin Laxity
Interventions
Fractional ablative laser
Device
Lead sponsor
Sciton
Industry
Eligibility
18 Years to 85 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 9, 2026, 12:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Surgical Scar Treatment With the Pulsed Dye Laser in Combination With a CO2 Laser

NCT02898350
View directory record Official record
Conditions
Scars
Interventions
Pulsed dye laser treatment, CO2 laser treatment, Combined PDL and CO2 laser treatment, Split PDL and CO2 Laser treatment
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
2
States / cities
Englewood, Colorado • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 13, 2016 · Synced Sep 9, 2026, 12:47 AM EDT
Recruiting Phase 4 Interventional

Remimazolam vs Propofol in Laser Burn Cases

NCT07213544
View directory record Official record
Conditions
Burn Scar, Hypertrophic Scarring, Procedural Sedation
Interventions
Remimazolam besylate, Propofol
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Sep 9, 2026, 12:47 AM EDT
Active, not recruiting Not applicable Interventional

CO2 Laser Revision for Burn Related Donor Site Scars

NCT04456127
View directory record Official record
Conditions
Burn Scar, Scar, Skin Graft Scar
Interventions
Fractional CO2 Laser
Procedure
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Sep 9, 2026, 12:47 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Laser Treatment for the Improvement of Scars and Scleroderma

NCT04567537
View directory record Official record
Conditions
Scars, Scleroderma
Interventions
Laser Treatment
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Sep 9, 2026, 12:47 AM EDT
Completed Not applicable Interventional

Randomized Control Trial of CO2 Laser to Treat Hypertrophic Burn Scar

NCT03692273
View directory record Official record
Conditions
Burns, Hypertrophic Scar
Interventions
Luminis ultrapulse fractional ablative carbon dioxide laser, 0.5mm punch biopsy
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 9, 2026, 12:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Lasers in the Treatment of Scars

NCT02988622
View directory record Official record
Conditions
Scar
Interventions
Fraxel Laser, CO2 Laser
Device
Lead sponsor
Marta Hemmingson-Van Beek
Other
Eligibility
18 Years to 120 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Sep 9, 2026, 12:47 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Compression and CO2 Laser for Leg Wounds

NCT04198454
View directory record Official record
Conditions
Wound Healing
Interventions
Compression bandages, Standard wound dressings, Fractional ablative carbon dioxide laser
Other · Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 9, 2026, 12:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of 1,550-nm Laser and Fractional Radiofrequency Microneedle for the Treatment of Acne Scars in Ethnic Skin

NCT03380845
View directory record Official record
Conditions
Acne Scars
Interventions
Fraxel Restore, Fractora
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced Sep 9, 2026, 12:47 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Fractional Handpiece With CO2 Laser: Fractional Ablative Laser Treatment of Vulvovaginal Atrophy

NCT03271944
View directory record Official record
Conditions
Vulvovaginal Atrophy
Interventions
CO2 Laser Treatment
Device
Lead sponsor
SHERRY Thomas
Other
Eligibility
40 Years to 80 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Agoura Hills, California
Source: ClinicalTrials.gov public record
Updated Mar 22, 2018 · Synced Sep 9, 2026, 12:47 AM EDT
Completed Not applicable Interventional Results available

Fractional Laser Assisted Steroid Therapy vs Intralesional Steroids in the Treatment of Keloids

NCT02996097
View directory record Official record
Conditions
Keloid
Interventions
The Lutronic electronic carbon dioxide (eCO2) Plus laser system, Intralesional Triamcinolone Acetonide
Device · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2020 · Synced Sep 9, 2026, 12:47 AM EDT
Completed Phase 4 Interventional Results available

Treatment of Keloids With Fractional Erbium Laser-Assisted 5-Fluorouracil Versus Laser-Assisted Corticosteroid

NCT04786210
View directory record Official record
Conditions
Keloid Scar
Interventions
Fractional erbium:YAG-assisted drug delivery of 5-fluorouracil, Fractional erbium:YAG-assisted drug delivery of triamcinolone acetonide
Combination Product
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 89 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 25, 2024 · Synced Sep 9, 2026, 12:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Fractional CO2 Laser on Poikiloderma of Civatte

NCT04581330
View directory record Official record
Conditions
Poikiloderma of Civatte
Interventions
DEKA SmartXide C02 laser
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 6, 2023 · Synced Sep 9, 2026, 12:47 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

1550nm Non-ablative Fractional Vs 1927nm Thulium Fractional Laser for the Treatment of Female Pattern Hair Loss

NCT06926023
View directory record Official record
Conditions
Female Pattern Baldness
Interventions
1550nm non-ablative fractional laser, 1927 thulium fractional laser
Device
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
35 Years to 65 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Sep 9, 2026, 12:47 AM EDT