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ClinicalTrials.gov public records Last synced Oct 27, 2026, 3:27 PM EDT

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Showing 697–720 of 918 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Fracture Clear all
Completed No phase listed Observational

Operatively Treated Open Pilon Fractures

NCT00689429
View directory record Official record
Conditions
Open Pilon Fractures
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Oct 27, 2026, 3:27 PM EDT
Not listed Not applicable Interventional

BFR DISTRAD: Blood Flow Restricted Training During Rehabilitation Following Distal Radius Fracture Repair

NCT02482727
View directory record Official record
Conditions
Distal Radius Fracture, Rehabilitation
Interventions
occlusion training with tourniquet (DELFI PTS ii portable tourniquet system)
Device
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2015
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 23, 2017 · Synced Oct 27, 2026, 3:27 PM EDT
Completed Not applicable Interventional Results available

Study to Find the Dose of Rapidly Administered Ketamine for Brief Painful Procedures in Children

NCT01669642
View directory record Official record
Conditions
Abscess, Fracture
Interventions
Ketamine
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
2 Years to 17 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Oct 27, 2026, 3:27 PM EDT
Completed Early Phase 1 Interventional

Role of Pregabalin in Treatment of Post-Op Pain in Fracture Patients

NCT00583869
View directory record Official record
Conditions
Post-operative Pain
Interventions
Placebo, Pregabalin
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 70 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 7, 2014 · Synced Oct 27, 2026, 3:27 PM EDT
Recruiting Not applicable Interventional

Clinical Outcomes Study of the Nexel Total Elbow

NCT02469662
View directory record Official record
Conditions
Elbow Joint Destruction, Post-traumatic Lesions, Ankylosed Joints, Advanced Rheumatoid Arthritis, Joint Instability or Loss of Motion, Acute Comminuted Articular Fracture of Elbow Joint Surfaces, Bone Loss Contributing to Elbow Instability, Bilateral Ankylosis From Causes Other Than Active Sepsis, Post-traumatic Arthritis, Degenerative Arthritis
Interventions
Nexel Total Elbow
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2036
U.S. locations
4
States / cities
Golden, Colorado • Charlotte, North Carolina • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 27, 2026, 3:27 PM EDT
Completed Not applicable Interventional Results available

A Direct-to-patient Intervention to Increase Rates of Osteoporosis Care

NCT01907269
View directory record Official record
Conditions
Osteoporosis
Interventions
Video-based Intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years and older · Female only
Enrollment
2,684 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
7
States / cities
Birmingham, Alabama • Los Angeles, California • Worcester, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2018 · Synced Oct 27, 2026, 3:27 PM EDT
Completed No phase listed Observational

Pediatric Supracondylar Humerus Fracture NIRS Study

NCT01808183
View directory record Official record
Conditions
Supracondylar Humerus Fracture
Interventions
Near Infrared Spectroscopy Pads
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
2 Years to 17 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 27, 2026, 3:27 PM EDT
Active, not recruiting Early Phase 1 Interventional

Hematoma Block Versus Bier Block for Closed Fracture Reduction

NCT05086224
View directory record Official record
Conditions
Distal Radius Fractures
Interventions
Hematoma Local Anesthetic Block Procedure with 1% Lidocaine, Bier Anesthetic Block Procedure with 1% Lidocaine
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Oct 27, 2026, 3:27 PM EDT
Not listed No phase listed Observational

Adequacy of Pain Management for Upper Extremity Fracture After Discharge From a Pediatric Emergency Depart

NCT01514097
View directory record Official record
Conditions
Fracture
Interventions
Not listed
Lead sponsor
Children's Hospitals and Clinics of Minnesota
Other
Eligibility
Up to 17 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Twin Cities, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 30, 2015 · Synced Oct 27, 2026, 3:27 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Osteogenesis Imperfecta Blood Pressure Study

NCT04169568
View directory record Official record
Conditions
Osteogenesis Imperfecta
Interventions
Manual cuff blood pressure
Procedure
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
1 Year to 35 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Oct 27, 2026, 3:27 PM EDT
Completed Not applicable Interventional Results available

Comparison of Occupational Therapy and Home Exercises for Adults With Operatively Treated Distal Radius Fractures

NCT00438750
View directory record Official record
Conditions
Distal Radius Fractures
Interventions
Independent Excercises, Occupational Therapy
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 8, 2012 · Synced Oct 27, 2026, 3:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Weight Loss on Bone in Men

NCT00472745
View directory record Official record
Conditions
Weight Loss, BMD
Interventions
Weight Loss, Weight Maintenance
Behavioral
Lead sponsor
Rutgers University
Other
Eligibility
50 Years to 72 Years · Male only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 27, 2026, 3:27 PM EDT
Withdrawn Phase 2 Interventional

Comparison of Low-dose Ketamine to Opioids in the Management of Acute Pain in Patients Presenting to the Emergency Department With Long Bone Fractures

NCT04061330
View directory record Official record
Conditions
Pain, Acute
Interventions
Ketamine, Morphine
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 27, 2026, 3:27 PM EDT
Completed No phase listed Observational

ICG Fluorescence Imaging in Open Fracture Trauma Patients

NCT04416412
View directory record Official record
Conditions
Trauma Injury
Interventions
Immunofluorescence Imaging
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
4
States / cities
Irvine, California • Baltimore, Maryland • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 27, 2026, 3:27 PM EDT
Completed Phase 2 Interventional Results available

Pioglitazone for Lung Cancer Chemoprevention

NCT00780234
View directory record Official record
Conditions
Lung Cancer, Endobronchial Dysplasia
Interventions
fluorescence bronchoscopy, quantitative high resolution CT scan, PIOGLITAZONE VS. PLACEBO 30 mg
Procedure · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
2
States / cities
Denver, Colorado • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 11, 2019 · Synced Oct 27, 2026, 3:27 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures

NCT06533904
View directory record Official record
Conditions
Trauma, Rib Fractures, Chest Wall Disorder, Respiratory Insufficiency, Pain, Chest, Rib Trauma, Rib Fracture Multiple, Respiratory Failure, Respiratory Distress Syndrome
Interventions
Percutaneous Cryoablation of Intercostal Nerves, Multi-modal pain regimen
Procedure · Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 27, 2026, 3:27 PM EDT
Recruiting No phase listed Observational

Investigating Periprosthetic Fracture Cultures in Arthroplasty

NCT06952738
View directory record Official record
Conditions
Periprosthetic Fracture Around Prosthetic Joint Implant
Interventions
Not applicable- observational study
Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 27, 2026, 3:27 PM EDT
Terminated Not applicable Interventional Results available

Light Therapy in the Treatment of Leg Pain

NCT00253981
View directory record Official record
Conditions
Tibial Fractures, Leg Injuries
Interventions
Monochromatic Near-Infrared Light Energy (MIRE)
Device
Lead sponsor
Samueli Institute for Information Biology
Other
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Jun 13, 2016 · Synced Oct 27, 2026, 3:27 PM EDT
Completed Phase 3 Interventional Results available

Exercise and Testosterone Therapy in Elderly Men With Physical Frailty

NCT00345969
View directory record Official record
Conditions
Physical Frailty, Hip Fracture, Elective Hip Replacement, Hypogonadism
Interventions
Transdermal Testosterone gel (1%), Supervised exercise training
Drug · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
65 Years and older · Male only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Oct 27, 2026, 3:27 PM EDT
Completed Not applicable Interventional Results available

Pelvis RCT: Impact of Surgery on Pain in Lateral Compression Type Pelvic Fractures

NCT02625766
View directory record Official record
Conditions
LC Pelvic Fracture
Interventions
LC fracture surgical fixation, LC fracture non-operative management
Procedure
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 80 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Indianapolis, Indiana • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 27, 2026, 3:27 PM EDT
Completed Not applicable Interventional Results available

Cast vs. Splints for Minimally Displaced Distal Radius Fractures in the Elderly

NCT02066857
View directory record Official record
Conditions
Radius; Fracture, Lower or Distal End
Interventions
Cast made of generic plaster or fiberglass cast material, Generic "off the shelf" removable splint
Device
Lead sponsor
Emory University
Other
Eligibility
60 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 24, 2017 · Synced Oct 27, 2026, 3:27 PM EDT
Completed No phase listed Observational

CT Imaging Evaluation of Humerus Fractures

NCT02170545
View directory record Official record
Conditions
Avascular Necrosis, Humeral Fractures
Interventions
Dual Energy Computed Tomography
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 6, 2020 · Synced Oct 27, 2026, 3:27 PM EDT
Completed Not applicable Interventional

fMRI Connectivity in Fracture Hip Patients

NCT02997930
View directory record Official record
Conditions
Postoperative Delirium, Postoperative Cognitive Dysfunction
Interventions
fMRI, Montreal Cognitive Assessment (MoCA), Digital Clock Drawing Test Command and Copy, Wide Range Achievement Test reading subtest, Hopkins Verbal Learning Test (HVLT), General Depression Scale (GDS)
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 99 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Oct 27, 2026, 3:27 PM EDT
Withdrawn No phase listed Observational

Operative Versus Nonoperative Treatment for Scapula Fractures

NCT00849771
View directory record Official record
Conditions
Scapula Fracture, Clavicle Fracture
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 13, 2015 · Synced Oct 27, 2026, 3:27 PM EDT