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ClinicalTrials.gov public records Last synced Oct 24, 2026, 10:37 AM EDT

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Showing 169–192 of 917 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Fracture Clear all
Completed No phase listed Observational

Stryker Universal Midface and Upper-Face Fixation System: A Retrospective Post Market Follow Up

NCT07245719
View directory record Official record
Conditions
Zygomatic Fractures, Orbital Fractures, Maxilla Fractures, Facial Fractures
Interventions
Upper-Face and/or Mid-Face modules (1.2 / 1.7 modules) of the Stryker Universal CMF System
Device
Lead sponsor
Stryker Craniomaxillofacial
Industry
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 24, 2026, 10:37 AM EDT
Completed Phase 3 Interventional Results available

Second Study of the Effect of Teriparatide on Hip Fracture Healing

NCT01473602
View directory record Official record
Conditions
Femur Neck Fracture
Interventions
Teriparatide, Placebo, Calcium supplementation, Vitamin D supplementation
Drug · Dietary Supplement
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
50 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
19
States / cities
San Diego, California • Golden, Colorado • Washington D.C., District of Columbia + 16 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2015 · Synced Oct 24, 2026, 10:37 AM EDT
Completed No phase listed Observational Results available

Zimmer® MotionLoc® in Distal Tibia Fractures

NCT02717546
View directory record Official record
Conditions
Distal Tibia Fractures
Interventions
Zimmer MotionLoc Screw
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
3
States / cities
Springfield, Illinois • Indianapolis, Indiana • Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 24, 2026, 10:37 AM EDT
Completed Not applicable Interventional

Early Motion After Volar Fixation for Distal Radius Fractures

NCT00955734
View directory record Official record
Conditions
Radius Fracture
Interventions
Early motion, Immobilization
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 29, 2015 · Synced Oct 24, 2026, 10:37 AM EDT
Completed Not applicable Interventional Results available

A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Proximal Tibial Fractures

NCT00429585
View directory record Official record
Conditions
Tibial Fractures
Interventions
reamed, interlocking intramedullary nail, locking periarticular plate
Device
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2020
U.S. locations
27
States / cities
Birmingham, Alabama • Davis, California • San Francisco, California + 22 more
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Oct 24, 2026, 10:37 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Early Mobilization Following Volar Locking Plate Fixation of Distal Radius Fractures

NCT05033938
View directory record Official record
Conditions
Distal Radius Fracture
Interventions
Early Mobilization Protocol, Late Mobilization Protocol
Procedure
Lead sponsor
Robert Wood Johnson Barnabas Health
Other
Eligibility
18 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Somerset, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 5, 2021 · Synced Oct 24, 2026, 10:37 AM EDT
Completed Early Phase 1 Interventional

Continuous Femoral Nerve Block With a Tibial Plateau Fracture

NCT02168959
View directory record Official record
Conditions
Tibial Plateau Fracture
Interventions
bupivacaine
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 14, 2016 · Synced Oct 24, 2026, 10:37 AM EDT
Completed Not applicable Interventional Results available

Early Percutaneous Cryoablation for Pain Control After Rib Fractures Among Elderly Patients

NCT04482582
View directory record Official record
Conditions
Rib Fractures
Interventions
Cryoneurolysis, Standard of Care
Radiation · Other
Lead sponsor
Stanford University
Other
Eligibility
65 Years and older
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 24, 2026, 10:37 AM EDT
Completed Not applicable Interventional Results available

An Imaging Framework for Clinically Testing New Treatments to Prevent Post-traumatic OA

NCT03809520
View directory record Official record
Conditions
Orthopedic Disorder, Trauma, Ankle Fractures, Post-traumatic Osteoarthritis
Interventions
pedCAT
Radiation
Lead sponsor
J L Marsh
Other
Eligibility
18 Years to 70 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 24, 2026 · Synced Oct 24, 2026, 10:37 AM EDT
Recruiting Not applicable Interventional

Immediate Vs. Delayed Weight Bearing Postoperative Protocol in Diabetic Ankle Fractures

NCT03966027
View directory record Official record
Conditions
Ankle Fractures
Interventions
Postoperative protocol (Immediate weight bearing), Postoperative Protocol (Delayed Weight Bearing)
Other
Lead sponsor
Kyle Schweser MD
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 24, 2026, 10:37 AM EDT
Recruiting Phase 2 Interventional

A Study of Romosozumab in People With Breast Cancer and Osteoporosis

NCT07776613
View directory record Official record
Conditions
Breast Cancer, Metastatic Breast Cancer (MBC)
Interventions
Romosozumab
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 24, 2026, 10:37 AM EDT
Recruiting Phase 4 Interventional

Randomized Controlled Trial for Ankle Fracture Pain Control

NCT03696199
View directory record Official record
Conditions
Ankle Fractures
Interventions
Long-Acting Local Anesthesia, Regional Anesthesia
Drug
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 24, 2026, 10:37 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Electromagnetic Treatment For Bone Loss After Forearm Fracture

NCT00067834
View directory record Official record
Conditions
Bone Disease, Metabolic, Osteopenia, Osteoporosis, Post-Traumatic
Interventions
Pulsing electromagnetic field (PEMF)
Device
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Dec 23, 2015 · Synced Oct 24, 2026, 10:37 AM EDT
Completed No phase listed Observational

Intraoperative Angioembolization in the Management of Pelvic Fracture-Related Hemodynamic Instability

NCT00755365
View directory record Official record
Conditions
Pelvic Fractures and Associated Hemodynamic Instability
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2019
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 22, 2019 · Synced Oct 24, 2026, 10:37 AM EDT
Completed Not applicable Interventional

A Study of Immediate and Delayed Closure of Type II and IIIa Open Tibia Fractures

NCT01315392
View directory record Official record
Conditions
Type II and IIa Open Tibia Fractures
Interventions
delayed closure, immediate wound closure
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
15 Years and older
Enrollment
451 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Oct 24, 2026, 10:37 AM EDT
Recruiting No phase listed Observational

Observational Study of Bone Complications in People With Post-menopausal Breast Cancer Who Have Stopped Treatment With Denosumab and Aromatase Inhibitors

NCT05590949
View directory record Official record
Conditions
Breast Cancer
Interventions
Physical Evaluation, Dual-energy X-ray absorptiometry scans, Trabecular Bone Score
Other · Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 24, 2026, 10:37 AM EDT
Recruiting Not applicable Interventional

RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

NCT06455085
View directory record Official record
Conditions
Osteoporosis, Osteoporotic Fractures, Fragility Fracture
Interventions
Augmented-Fracture Liaison Service Arm, Enhanced Usual Care Arm
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years and older
Enrollment
2,634 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
23
States / cities
Birmingham, Alabama • Scottsdale, Arizona • North Little Rock, Arkansas + 19 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 24, 2026, 10:37 AM EDT
Completed No phase listed Observational

Operatively Treated Open Pilon Fractures

NCT00689429
View directory record Official record
Conditions
Open Pilon Fractures
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 20, 2017 · Synced Oct 24, 2026, 10:37 AM EDT
Not listed Not applicable Interventional

Surgical Versus Nonsurgical Treatment of Fibular Fractures: A Prospective Randomized Study

NCT02032966
View directory record Official record
Conditions
Ankle Fracture, Malleolus Fracture, Medial Malleolus Fracture, Bimalleolar Fracture, Trimalleolar Fracture
Interventions
Nonsurgical, Surgical
Procedure
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
Chattanooga, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 28, 2018 · Synced Oct 24, 2026, 10:37 AM EDT
Completed Not applicable Interventional

Use of Continuous Passive Motion in the Post-Operative Treatment of Intra-articular Knee Fractures

NCT00591929
View directory record Official record
Conditions
Intra-articular Knee Fractures
Interventions
Continuous Passive Motion
Other
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2013 · Synced Oct 24, 2026, 10:37 AM EDT
Completed Not applicable Interventional

Rehabilitation Strategies to Improve Outcomes For Patients With a Lower Extremity Fracture

NCT05274022
View directory record Official record
Conditions
Femoral Fracture, Tibial Fractures
Interventions
Standard of Care Physical Therapy Program, Speed Walking Intervention
Other
Lead sponsor
Brian W. Noehren
Other
Eligibility
18 Years to 50 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Lexington, Kentucky • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 24, 2026, 10:37 AM EDT
Completed Phase 4 Interventional Results available

Pre-operative Alcohol Skin Solutions in Fractured Extremities

NCT03523962
View directory record Official record
Conditions
Surgical Site Infection, Unplanned Fracture-Related Reoperation, Open Appendicular Fracture, Closed Lower Extremity Fracture, Pelvic Fracture
Interventions
DuraPrep, ChloraPrep
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
8,485 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
24
States / cities
Irvine, California • Los Angeles, California • San Jose, California + 20 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 24, 2026, 10:37 AM EDT
Completed Not applicable Interventional

PENG vs. FIC Block for Hip Fracture ED Patients

NCT05102760
View directory record Official record
Conditions
Pain, Hip Fracture
Interventions
Nerve Block using FIC Proceedure, Nerve Block using PENG Proceedure
Procedure
Lead sponsor
Antonios Likourezos
Other
Eligibility
18 Years to 110 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 24, 2026, 10:37 AM EDT
Not yet recruiting Not applicable Interventional

Weight Bearing After Pelvis and Acetabulum Fracture Fixation

NCT07189156
View directory record Official record
Conditions
Pelvis Fractures, Acetabulum Fractures
Interventions
Immediate Weight Bearing Pelvis, Delayed Weight Bearing Pelvis, Immediate Weight Bearing Acetabulum, Delayed Weight Bearing Acetabulum
Other
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
6
States / cities
Birmingham, Alabama • Colton, California • Indianapolis, Indiana + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Oct 24, 2026, 10:37 AM EDT