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ClinicalTrials.gov public records Last synced Oct 20, 2026, 6:15 AM EDT

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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Free gingival graft Clear all
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Oral Mucosa Wound Healing After Gingival Recession Treatment in Diabetic Patients. A Clinical Study.

NCT07470281
View directory record Official record
Conditions
Diabetes Mellitus, Gingival Recession, Generalized, Gingival Recession, Localized
Interventions
Coronally Advance Flap associated with connective tissue graft (CAF+CTG)
Procedure
Lead sponsor
Mauro Santamaria
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 20, 2026, 6:15 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Dimensional Changes: Randomized Clinical Trial

NCT05684068
View directory record Official record
Conditions
Gingival Recession
Interventions
Gum Graft Placed on Denuded Bone, Gum Graft Placed on Split Thickness Periosteal Bed Preparation
Procedure
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 95 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2028 – 2031
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 20, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Clinical and Histological Outcomes of Allogenic Amnion Chorion Membrane in the Healing of Free Gingival Graft Donor Site

NCT03713073
View directory record Official record
Conditions
Palatal Wound
Interventions
Allogenic amnion chorion membrane, Collagen dressing
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 19, 2022 · Synced Oct 20, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

To Measure Pain Perception Following De-Epithelized Free Gingival Graft Harvesting

NCT03895476
View directory record Official record
Conditions
Gingival Recession, Palate; Wound
Interventions
palatal wound will be cover with collagen and sutures, palatal wound covered with platelet rich fibrin, palatal wound covered with a collagen sponge and cyanoacrylate, palatal wound covered with a stent
Diagnostic Test
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 70 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 23, 2024 · Synced Oct 20, 2026, 6:15 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Guided Bone Regeneration Around Immediate Implants

NCT01628367
View directory record Official record
Conditions
Missing Tooth
Interventions
Minimally Traumatic Tooth Extraction, Immediate Implant Placement, Bone Graft Placement, Membrane placement, Collagen plug placement, Medications
Procedure · Device · Biological + 1 more
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 100 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 20, 2017 · Synced Oct 20, 2026, 6:15 AM EDT
Not yet recruiting Not applicable Interventional

Free Soft Tissue Grafts FSTG) Using Autograft Palatal Donor Tissue vs. Xenograft Collagen Matrix (Zderm™)

NCT07713199
View directory record Official record
Conditions
Gingival Recession Localized Moderate, Dental Implant
Interventions
Zderm
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 89 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 20, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical and Histological Assessment of Free Gingival Graft or Collagen Matrix for Socket Sealing After Bone Grafting

NCT05448040
View directory record Official record
Conditions
Socket Sealing, Free Gingival Graft, Collagen Membrane
Interventions
Socket preservation
Procedure
Lead sponsor
Universidade Salgado de Oliveira
Other
Eligibility
18 Years to 55 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 7, 2022 · Synced Oct 20, 2026, 6:15 AM EDT
Not yet recruiting Not applicable Interventional

Keratinized Tissue Augmentation Using Augmented Gingival Matrix Compared to Free Gingival Graft Around Implants

NCT07863882
View directory record Official record
Conditions
Keratinized Tissue Augmentation Around Dental Implants
Interventions
Augmented Gingival Matrix graft, Free Gingival Graft
Device · Procedure
Lead sponsor
The Forsyth Institute
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 20, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Procedures for Improving the Mucosa Around Implants

NCT01944267
View directory record Official record
Conditions
Keratinized Mucosa, Dental Implants
Interventions
Apically positioned flap, Free Gingival Graft, apically positioned flap with Mucograft
Procedure
Lead sponsor
Tufts University
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Oct 20, 2026, 6:15 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Palatal Wound Healing After Free Gingival Graft Harvest in Diabetic Patients: A Clinical Trial

NCT07500935
View directory record Official record
Conditions
Diabetes Mellitus, Gingival Recession, Generalized, Gingival Recession, Localized
Interventions
Free gingival graft
Procedure
Lead sponsor
Mauro Santamaria
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 20, 2026, 6:15 AM EDT
Completed Not applicable Interventional

Pinhole Surgical Technique Compared to Connective Tissue Graft in Treatment of Gingival Recession

NCT04356391
View directory record Official record
Conditions
Periodontal Diseases
Interventions
Connective Tissue Graft Technique, Pinhole Surgical Technique
Procedure
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
19 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated May 25, 2023 · Synced Oct 20, 2026, 6:15 AM EDT
Not listed Not applicable Interventional

Free Gingival Grafts (FGGs) in Mandibular Posterior Sites

NCT04099680
View directory record Official record
Conditions
Lack of Keratinized Tissue
Interventions
Partial thickness recipient bed, Full thickness recipient bed, Bone screw (FDA approved bone screw), Periosteal sutures, Sling sutures, Sling sutures around screws
Procedure · Device
Lead sponsor
Ohio State University
Other
Eligibility
35 Years to 70 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 10, 2024 · Synced Oct 20, 2026, 6:15 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Collagen Matrix + rhPDGF-BB vs Connective Tissue Graft for the Treatment of Peri-implant Soft Tissue Dehiscences

NCT05576922
View directory record Official record
Conditions
Implant Complication
Interventions
Prosthetic-surgical approach + autogenous graft, Prosthetic-surgical approach + graft substitute
Other
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Oct 20, 2026, 6:15 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Buccal Graft + Collagen Matrix Versus Free Gingival Graft for Keratinized Mucosa Augmentation at Implant Sites

NCT05844475
View directory record Official record
Conditions
Surgery
Interventions
Conventional Free Gingival Graft Approach (FGG), Buccal Strip Graft with a collagen matrix (bSG + CM)
Procedure
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced Oct 20, 2026, 6:15 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

The Impact of a Known Bioactive Agent on the Resolution of Alveolar Socket Preservation

NCT02802436
View directory record Official record
Conditions
Healing of Extraction Socket
Interventions
Extraction with socket graft
Procedure
Lead sponsor
Boston University
Other
Eligibility
20 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Oct 20, 2026, 6:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vertical Soft Tissue Augmentation With CTG vs ADM

NCT05729607
View directory record Official record
Conditions
Implant Complication
Interventions
Vertical soft tissue augmentation
Procedure
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years to 99 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Oct 20, 2026, 6:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix

NCT04920136
View directory record Official record
Conditions
Gingival Recession, Lack of Keratinized Attached Peri-implant Mucosa, Thin Gingiva
Interventions
Strip Free gingival graft (SGG) + Acellular Dermal Matrix graft (ADM), Free Gingival graft
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 20, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gingival Augmentation Around Implants During Maintenance

NCT02904551
View directory record Official record
Conditions
Failure of Dental Implant Due to Lack of Attached Gingiva
Interventions
Free gingival graft, Oral prophylaxis
Procedure
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 11, 2024 · Synced Oct 20, 2026, 6:15 AM EDT
Completed Not applicable Interventional

A Pilot Clinical Trial of Gintuit (TM)in Establishing a Functional Zone of Attached Gingiva

NCT01547962
View directory record Official record
Conditions
Gingival Recession
Interventions
Gintuit, autologous Free Gingival Graft (FGG)
Device · Other
Lead sponsor
Organogenesis
Industry
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 9, 2012 · Synced Oct 20, 2026, 6:15 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of StellaLife Oral Care Recovery Kit on Palatal Wound Healing After Free Gingival Graft

NCT05921513
View directory record Official record
Conditions
Wound Heal
Interventions
Free Gingival Graft Procedure
Procedure
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 27, 2023 · Synced Oct 20, 2026, 6:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

To Compare Free Gingival Grafts and Connective Tissue Grafts Around Implants With Lack of Keratinized Mucosa

NCT03338686
View directory record Official record
Conditions
Dental Implants, Alveolar Mucosa
Interventions
Free Gingival Graft (FGG), Connective Tissue Graft followed by Laser Gingivoplasty
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Oct 20, 2026, 6:15 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Star Matrix vs Autogenous Graft for Gingival Augmentation: Split-Mouth RCT

NCT07440303
View directory record Official record
Conditions
Lack of Keratinized Gingiva, Mucogingival Deformity - Insufficient Keratinized Tissue
Interventions
Starmatrix collagen membrane, Autogenous gingival graft
Device · Other
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
20 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 20, 2026, 6:15 AM EDT
Enrolling by invitation Not applicable Interventional

Modified Coronally Advanced Tunnel for Mandibular Lingual Root Coverage

NCT07590960
View directory record Official record
Conditions
Gingival Recession, Mucogingival Deformity - Insufficient Keratinized Tissue
Interventions
Modified Coronally Advanced Tunnel with Connective Tissue Graft
Procedure
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 20, 2026, 6:15 AM EDT
Completed Not applicable Interventional Results available

Patient Outcomes and Gingival Blood Flow Using Laser Doppler Flowmetry Following the Use of Episil on Free Gingival Graft Donor Sites

NCT03350724
View directory record Official record
Conditions
Pain From Free Gingival Graft
Interventions
episil wound dressing, PeriAcryl90 wound dressing
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 17, 2018 · Synced Oct 20, 2026, 6:15 AM EDT