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Showing 289–312 of 513 matching trials from the live ClinicalTrials.gov search.
Completed Early Phase 1 Interventional Accepts healthy volunteers

Sevoflurane's Effect on Neurocognition Study

NCT06044740
Conditions
Anesthesia, Pain, Amnesia
Interventions
Sevoflurane, Peripheral Nerve Stimulation
Drug · Device
Lead sponsor
Keith M Vogt
Other
Eligibility
18 Years to 59 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Spinal Cord Injuries, Tetraplegia, Cervical Spinal Cord Injury
Interventions
transcranial Random Noise Stimulation (tRNS), transcranial Direct Current Stimulation (tDCS), sham-stimulation
Other
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Insomnia
Interventions
PeakSleep, Sham
Device
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 70 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Inflammatory Myelopathies
Interventions
FES Cycling, Cycling without FES, Lumbar puncture, Mood assessment
Device · Procedure · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
Lutherville, Maryland
Conditions
Anxiety
Interventions
CES treatment using Alpha-Stim technology, Shame CES Treatment
Device
Lead sponsor
Wyndhurst Counseling Center
Other
Eligibility
18 Years to 65 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
2
States / cities
Lynchburg, Virginia
Conditions
Chronic Low Back Pain
Interventions
Epidural electrical spinal cord stimulator
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Foot Drop
Interventions
Cionic Neural Sleeve
Device
Lead sponsor
Cionic, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
San Francisco, California • Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

Vitamin D and Calcium Study

NCT00857831
Conditions
Spinal Cord Injury
Interventions
Vitamin D and Calcium
Dietary Supplement
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Stroke, Rehabilitation, Hand
Interventions
transcranial direct current stimulation and electrical stimulator
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Cerebral Palsy
Interventions
Combined functional electrical stimulation and robotic gait training
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 12 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Healthy Volunteers, no Condition, Basic Science
Interventions
Transcranial Focused Ultrasound Stimulation, Electroencephalography, Magnetic Resonance Imaging
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
21 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Cambridge, Massachusetts
Active, not recruiting Not applicable Interventional

Pilot/Pivotal Study of DBS+Rehab After Stroke

NCT05701280
Conditions
Stroke, Upper Extremity Paresis
Interventions
Deep Brain Stimulation, Rehabilitation
Device · Other
Lead sponsor
Enspire DBS Therapy, Inc.
Industry
Eligibility
21 Years and older
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
9
States / cities
Phoenix, Arizona • Baltimore, Maryland • Boston, Massachusetts + 6 more
Conditions
Spinal Cord Injury
Interventions
Arm and hand training
Other
Lead sponsor
University of Miami
Other
Eligibility
16 Years to 70 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Miami, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise Rehabilitation in Veterans With PAD

NCT02607046
Conditions
Peripheral Arterial Disease, Intermittent Claudication
Interventions
Exercise training, NMES
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 80 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Withdrawn Not applicable Interventional Accepts healthy volunteers

New Mothers Alpha-Stim

NCT04770181
Conditions
Anxiety, Depression, Insomnia, Sleep Quality
Interventions
Alpha-Stim AID CES (Active Comparator), Alpha-Stim AID CES (Sham Comparator)
Device
Lead sponsor
Christina Murphey, RN, PhD
Individual
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Austin, Texas • Corpus Christi, Texas
Conditions
Somatosensory Function, Balance Control, Mobility
Interventions
transcranial direct current stimulation, active sham stimulation
Device
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Roslindale, Massachusetts
Conditions
Episodic Memory
Interventions
Brain stimulation
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Results available

Functional Electrical Stimulation Use in Trans-tibial Amputations

NCT02931396
Conditions
Traumatic Amputation of Lower Extremity
Interventions
FES
Device
Lead sponsor
Alicia Koontz
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Stroke, Acute, Stroke, Hemiparesis
Interventions
NMES device with EMG-triggered and Cyclic capabilities
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 89 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
3
States / cities
Akron, Ohio • Cincinnati, Ohio • Cleveland, Ohio
Withdrawn Not applicable Interventional Accepts healthy volunteers

Cognitive & Motor Training After Stroke For Everyday Walking Restoration

NCT01160653
Conditions
Stroke
Interventions
FES-IM, Cognitive training
Device · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

TENS Effectiveness and Knee Osteoarthritis in Humans

NCT01354054
Conditions
Knee Osteoarthritis
Interventions
High Frequency TENS, Low frequency TENS, Placebo TENS
Procedure
Lead sponsor
University of Iowa
Other
Eligibility
30 Years to 95 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Iowa City, Iowa
Not yet recruiting Early Phase 1 Interventional

Individualized fMRI-guided TMS for Depression

NCT07804459
Conditions
Depression, Major Depressive Disorder (MDD), Depression - Major Depressive Disorder, Persistent Depressive Disorder, PDD, MDD
Interventions
Active Repetitive Transcranial Magnetic Stimulation (rTMS), Sham Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Nephrotic Syndrome in Children, Minimal Change Disease, Focal Segmental Glomerulosclerosis
Interventions
trascutaneous auricular vagus nerve stimulation, Sham device
Device
Lead sponsor
Northwell Health
Other
Eligibility
3 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
New Hyde Park, New York • Philadelphia, Pennsylvania
Conditions
Total Knee Arthroplasty, Osteoarthritis
Interventions
Neuromuscular electrical stimulation, Voluntary exercise
Procedure
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
45 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
1
States / cities
Newark, Delaware