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ClinicalTrials.gov public records Last synced Oct 21, 2026, 8:29 AM EDT

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Showing 1–24 of 43 matching trials from the live ClinicalTrials.gov search.
Conditions
Gastroesophageal Reflux, Nervous System Diseases, Fundoplication, Enteral Nutrition
Interventions
Fundoplication, Gastrojejunal (GJ) feeding tube
Procedure
Lead sponsor
University of Utah
Other
Eligibility
6 Months to 18 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Achalasia, Gastric Outlet Obstruction, Gastroparesis, GERD, Reflux, Fistula, Benign Neoplasm
Interventions
Endoscopic Surgery
Procedure
Lead sponsor
Advanced Endoscopy Research, Robert Wood Johnson Medical School Rutgers University
Other
Eligibility
Not listed
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New Brunswick, New Jersey
Conditions
GastroEsophageal Reflux Disease
Interventions
Not listed
Lead sponsor
American Gastroenterological Association
Other
Eligibility
18 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
10
States / cities
Huntington Beach, California • Englewood, Colorado • Chicago, Illinois + 7 more
Conditions
Esophagogastric Junction Distensibility, Hiatal Hernia
Interventions
EndoFLIP
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Charlotte, North Carolina
Conditions
Non-acid Reflux Disease
Interventions
anti-reflux surgery
Procedure
Lead sponsor
United States Naval Medical Center, Portsmouth
Federal
Eligibility
17 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Portsmouth, Virginia
Conditions
Gastroesophageal Reflux Disease (GERD), Laryngopharyngeal Reflux (LPR), Reflux Disease, Gastro-Esophageal, Motility Disorder
Interventions
Transoral Incisionless Fundoplication
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Gastroesophageal Reflux Disease, Bronchopulmonary Dysplasia
Interventions
Fundoplication
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
24 Weeks to 1 Year
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Houston, Texas
Terminated Not applicable Interventional Results available

Hernia Reduction Prior to Scheduled TIF Completion

NCT03280121
Conditions
Fundoplication
Interventions
EsophyX ZR transoral device
Device
Lead sponsor
EndoGastric Solutions
Industry
Eligibility
18 Years to 72 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
3
States / cities
Elkhart, Indiana • Iron River, Michigan • Sparks, Nevada
Conditions
Acquired Hyperinsulinemic Hypoglycemia
Interventions
Avexitide
Drug
Lead sponsor
Dr. Tracey McLaughlin, MD
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Reflux, Gastroesophageal Reflux Disease (GERD)
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
16 Years and older
Enrollment
647 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
3
States / cities
Baltimore, Maryland • Durham, North Carolina • Cleveland, Ohio
Conditions
Reflux
Interventions
esophageal stitches during fundoplication, no esophageal stitches placed during fundoplication
Procedure
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
1 Day to 7 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Kansas City, Missouri
Conditions
Gastroesophageal Reflux Disease (GERD)
Interventions
Medigus SRS endoscopic stapling system
Device
Lead sponsor
Aviel Roy-Shapira, M.D.
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
2
States / cities
San Diego, California • Indianapolis, Indiana
Conditions
Gastroesophageal Reflux Disease
Interventions
no intervention, database study
Other
Lead sponsor
Indiana University
Other
Eligibility
13 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Fundoplication in Laparoscopic PEH Repair Based on FLIP

NCT05807763
Conditions
Paraesophageal Hernia
Interventions
Laparoscopic paraesophageal hernia repair without fundoplication
Procedure
Lead sponsor
The Foundation for Surgical Innovation and Education
Other
Eligibility
18 Years and older
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
2
States / cities
Evanston, Illinois • Portland, Oregon
Conditions
Barrett Esophagus, Transoral Incisionless Fundoplication
Interventions
TIF
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Gastroesophageal Reflux Disease (GERD)
Interventions
Transoral Incisionless Fundoplication
Device
Lead sponsor
EndoGastric Solutions
Industry
Eligibility
18 Years to 85 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Ocala, Florida • Salem, Kentucky
Conditions
Gastroesophageal Reflux Disease
Interventions
Questionnaires to evaluate QOL, Questionnaires to evaluate heartburn and quality of life, Questionnaire to evaluate satisfaction with treatment, Questionnaire to evaluate presence or absence of pain
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2050
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Terminated No phase listed Observational

Growth in Children With HLHS

NCT00277992
Conditions
Congenital Disorders
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Up to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2001
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
GERD, Hiatal Hernia
Interventions
LAPAROSCOPIC PARAESOPHAGEAL HIATAL HERNIA REPAIR COMBINED WITH TRANSORAL INCISIONLESS FUNDOPLICATION
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
22 Years to 80 Years
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
7
States / cities
Irvine, California • Los Angeles, California • Englewood, Colorado + 4 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

The EndoGastric Solutions TEMPO Trial

NCT01647958
Conditions
Gastroesophageal Reflux Disease (GERD)
Interventions
EsophyX System with SerosaFuse fasteners, PPI
Device · Drug
Lead sponsor
EndoGastric Solutions
Industry
Eligibility
18 Years to 80 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Redmond, Washington
Conditions
Hiatal Hernia Large, Gastro Esophageal Reflux, Hiatal Hernia, Hiatal Hernia, Paraesophageal, Reflux, Gastroesophageal, Reflux Acid
Interventions
LINX Reflux Management System, Fundoplication
Device · Procedure
Lead sponsor
Foregut Research Foundation
Other
Eligibility
21 Years and older
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
6
States / cities
Los Angeles, California • Lone Tree, Colorado • Coral Springs, Florida + 3 more
Conditions
Swallowing Disorders, Achalasia, Outlet Obstruction, Gastric, Diffuse Esophageal Spasm
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Conditions
General Laparoscopic Surgery Candidate, Bariatric Laparoscopic Surgery Candidate
Interventions
AutoLap
Device
Lead sponsor
M.S.T. Medical Surgery Technology LTD.
Industry
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Burlington, Massachusetts
Completed No phase listed Observational

Gastroparesis Registry 2

NCT01696747
Conditions
Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis
Interventions
Not listed
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
506 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
6
States / cities
Louisville, Kentucky • Baltimore, Maryland • Boston, Massachusetts + 3 more