Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 9, 2026, 6:11 PM EDT

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Showing 1–24 of 30 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Diabetic Retinopathy
Interventions
Digital Retinography System
Device
Lead sponsor
University of Florida
Other
Eligibility
9 Years to 26 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
3
States / cities
De Leon Springs, Florida • Gainesville, Florida • Orlando, Florida
Conditions
Microvascular Disease, Retinal Disease
Interventions
XyCAM CRE Imaging
Device
Lead sponsor
Stuart Terry Eye Associates
Other
Eligibility
21 Years to 100 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
San Antonio, Texas
Recruiting No phase listed Observational Accepts healthy volunteers

Assessment of AI Program 'DRISTi' as a Screening Tool

NCT07222293
Conditions
Diabetic Retinopathy (DR)
Interventions
Fundus Image Grading
Diagnostic Test
Lead sponsor
Artelus AI
Industry
Eligibility
21 Years and older
Enrollment
900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Oxford, North Carolina • Raleigh, North Carolina
Active, not recruiting No phase listed Observational

Camera Qualification Study

NCT05808699
Conditions
Diabetic Retinopathy
Interventions
handheld fundus camera
Device
Lead sponsor
Digital Diagnostics, Inc.
Industry
Eligibility
22 Years and older
Enrollment
626 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
9
States / cities
Norco, California • Pomona, California • Jacksonville, Florida + 6 more
Withdrawn No phase listed Observational Accepts healthy volunteers

Non-Invasive Imaging of the Human Eye

NCT02432898
Conditions
Willing and Able Subjects for Ocular Imaging
Interventions
3D OCT-1, 3D OCT-2000, DRI OCT-1, NW-300, CT-1P, TRK-2P, SP-1P, SL-D701, MC-4S
Device
Lead sponsor
Topcon Medical Systems, Inc.
Industry
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Oakland, New Jersey
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Ocular Screening in Children and Young Adults at Risk for Increased Intracranial Pressure

NCT03286426
Conditions
Intracranial Pressure Increase
Interventions
Pictor
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
Up to 21 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Philadelphia Telemedicine Glaucoma Detection and Follow-Up Study

NCT02390245
Conditions
Glaucoma, Glaucoma Suspect, Diabetic Retinopathy, Ocular Hypertension, Cataract, Branch Retinal Vein Occlusion, Branch Retinal Arterial Occlusion, Central Retinal Vein Occlusion, Central Retinal Artery Occlusion, Epi-retinal Membrane, Macular Degeneration, Drusen, Loss of Vision
Interventions
Free Eye Screenings, Enhanced Intervention, Usual Care
Other
Lead sponsor
Wills Eye
Other
Eligibility
40 Years and older
Enrollment
906 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed No phase listed Observational Accepts healthy volunteers

OCT Angiography Software Evaluation Study

NCT04701931
Conditions
Retina Condition Followed by Fluorescein Angiography Imaging
Interventions
Maestro2 OCTA, Cirrus HD-OCT 5000, TRC-50DX
Device
Lead sponsor
Topcon Corporation
Industry
Eligibility
22 Years and older
Enrollment
135 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Santa Ana, California • Augusta, Georgia
Completed Not applicable Interventional Accepts healthy volunteers

Optic Disc Photograph Collection Study

NCT05532410
Conditions
Retina Disease, Glaucoma, Normal
Interventions
Fundus Camera
Device
Lead sponsor
Optos, PLC
Industry
Eligibility
22 Years and older
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Retinopathy, Retinal Vein Occlusion, Diabetic Retinopathy, Macular Degeneration
Interventions
Fluorescein sodium and Zeiss FF450 fundus camera, MB-102 and Zeiss FF450 fundus camera, Fluorescein sodium and commercially available optical angiography imaging system, MB-102 and commercially available optical angiography imaging system
Combination Product
Lead sponsor
MediBeacon
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Geographic Atrophy, Age-Related Macular Degeneration
Interventions
OcuMet Beacon
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
50 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Not listed Not applicable Interventional

RetinaVue Diabetic Screening

NCT03343730
Conditions
Diabetic Retinopathy
Interventions
Non-mydriatic color fundus photography with the RetinaVue camera, Referral for dilated eye exam with an eye care professional
Diagnostic Test
Lead sponsor
Bassett Healthcare
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Cooperstown, New York
Completed No phase listed Observational Accepts healthy volunteers

NW500 Non-Mydriatic Retinal Camera Clinical Performance Study

NCT05286502
Conditions
Fundus Photography
Interventions
fundus photography
Device
Lead sponsor
Topcon Corporation
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Oakland, New Jersey
Completed No phase listed Observational Accepts healthy volunteers

Topcon DRI OCT Triton With SS-OCT Angio Software Evaluation Study

NCT04201340
Conditions
Fluorescein Angiography Imaging
Interventions
DRI OCT Triton with SS-OCT Angio software, Cirrus HD-OCT 5000, TRC-50DX
Device
Lead sponsor
Topcon Corporation
Industry
Eligibility
22 Years and older
Enrollment
211 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Age Related Macular Degeneration
Interventions
adaptive optics AO-OCT/AF instrument
Diagnostic Test
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
60 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Headache, Acute, Focal Neurologic Disease, Severely Elevated Blood Pressure, Acute Visual Loss
Interventions
Use of Non-dilated retinal photography
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
705 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Atlanta, Georgia
Completed No phase listed Observational Accepts healthy volunteers

Triton Fundus Autofluorescence and Fluorescein Angiography

NCT03107104
Conditions
Medical Need for Fluorescein Angiography Imaging
Interventions
Topcon DRI OCT Triton (plus), TRC-50DX retinal camera
Device
Lead sponsor
Topcon Medical Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New York, New York
Completed No phase listed Observational Accepts healthy volunteers

Multimodal Ocular Imaging in Neurodegeneration

NCT03699644
Conditions
Alzheimer Disease, Alzheimer Dementia, Frontotemporal Dementia
Interventions
Spectral-Domain Optical Coherence Tomography (SD-OCT), Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), Comprehensive Ophthalmic Examination, Fundus Photography
Device · Diagnostic Test
Lead sponsor
University of Michigan
Other
Eligibility
45 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Eye Diseases
Interventions
WiSLO, Volk Pictor Plus™
Device
Lead sponsor
Duke University
Other
Eligibility
30 Days and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Diabetes Mellitus, Diabetic Retinopathy
Interventions
AEYE Software Device
Device
Lead sponsor
AEYE Health Inc
Industry
Eligibility
22 Years and older
Enrollment
531 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Louisville, Kentucky
Completed Not applicable Interventional Accepts healthy volunteers

Precision Study of CLAiR AI Software

NCT07747233
Conditions
Cardiovascular Risk
Interventions
CLAiR Artificial Intelligence Software
Device
Lead sponsor
Toku Eyes Ltd
Industry
Eligibility
40 Years to 75 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
Homer Glen, Illinois • Canton, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2)

NCT04995341
Conditions
Retinopathy of Prematurity
Interventions
Investigational ultracompact OCT and OCTA system, retinal photographs
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
236 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Durham, North Carolina • Philadelphia, Pennsylvania
Completed No phase listed Observational Accepts healthy volunteers

Assessment of Prototype Hand-Held Fundus Camera

NCT01899222
Conditions
Normal Subject Population
Interventions
Handheld fundus photography
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Rochester, New York
Conditions
Diabetic Retinopathy, Diabetic Macular Edema
Interventions
Camera Imaging
Device
Lead sponsor
Digital Diagnostics, Inc.
Industry
Eligibility
22 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio