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ClinicalTrials.gov public records Last synced Sep 10, 2026, 9:53 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Fusion--Instrumented Clear all
Active, not recruiting No phase listed Observational

Collecting Bone Graft During Spinal Decompression and Posterolateral Lumbar Fusion to Better Define Bone Making Cells

NCT01409954
View directory record Official record
Conditions
Pseudarthrosis After Fusion or Arthrodesis
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 10, 2026, 9:53 PM EDT
Completed Not applicable Interventional Results available

OsteoStrux™ Collagen Ceramic Scaffold in Instrumented Lumbar Spine Fusion

NCT01873586
View directory record Official record
Conditions
Degenerative Changes, Stenosis, Spondylosis
Interventions
Posterolateral Fusion
Procedure
Lead sponsor
SeaSpine, Inc.
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Kenmore, New York
Source: ClinicalTrials.gov public record
Updated Jun 16, 2019 · Synced Sep 10, 2026, 9:53 PM EDT
Recruiting Not applicable Interventional

FIBERGRAFT Aeridyan Posterolateral Fusion Study

NCT07059065
View directory record Official record
Conditions
Degenerative Spine Disease
Interventions
FIBERGRAFT™ Aeridyan Matrix Bone Graft Substitute, Demineralized Bone Matrix
Device
Lead sponsor
DePuy Synthes Products, Inc.
Industry
Eligibility
18 Years and older
Enrollment
316 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
5
States / cities
Sacramento, California • Chicago, Illinois • Lexington, Kentucky + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 10, 2026, 9:53 PM EDT
Completed Not applicable Interventional

Comparison of nanOss Bioactive With Autograft and Bone Marrow Aspirate to Autograft in the Posterolateral Spine

NCT01968993
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
Interventions
nanOss Bioactive - posterolateral gutter
Device
Lead sponsor
Pioneer Surgical Technology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
3
States / cities
La Jolla, California • San Francisco, California • Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 7, 2016 · Synced Sep 10, 2026, 9:53 PM EDT
Completed Not applicable Interventional

Post Marketing Study of MagnetOs Putty Compared to Local Autograft in Patients Undergoing Posterolateral Lumbar Fusion

NCT04679896
View directory record Official record
Conditions
Degenerative Disc Disease, Spine Fusion
Interventions
MagnetOs Putty
Device
Lead sponsor
Kuros Biosurgery AG
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Paducah, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 12, 2024 · Synced Sep 10, 2026, 9:53 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Study to Assess the Performance of MagnEtOs Flex Matrix Compared to Cellular Allograft

NCT06415123
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
MagnetOs Flex Matrix
Device
Lead sponsor
Research Source
Network
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Southfield, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 10, 2026, 9:53 PM EDT
Completed Not applicable Interventional Results available

Efficacy and Safety of Accell Evo3 Demineralized Bone Matrix (DBM) in Instrumented Posterolateral Lumbar Spine Fusion

NCT01430299
View directory record Official record
Conditions
Stenosis, Spondylosis, Degenerative Changes
Interventions
Demineralized Bone Matrix, rh-BMP2
Device
Lead sponsor
SeaSpine, Inc.
Industry
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2018 · Synced Sep 10, 2026, 9:53 PM EDT
Active, not recruiting No phase listed Observational

Evaluation of Symphony™ Posterior Cervical System for Surgical Treatment of Adult Cervical Deformity

NCT04912674
View directory record Official record
Conditions
Cervical Deformity
Interventions
Symphony OCT System
Device
Lead sponsor
International Spine Study Group Foundation
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
6
States / cities
Sacramento, California • Denver, Colorado • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 10, 2026, 9:53 PM EDT
Terminated Not applicable Interventional Results available

Bone Marrow Aspirate Concentration in Posterior Cervical Fusion

NCT02068547
View directory record Official record
Conditions
Cervical Myelopathy, Radiculopathy
Interventions
locally harvested autograft, demineralized bone matrix, and cadaveric allograft, Bone Marrow Aspirate
Biological
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Sep 10, 2026, 9:53 PM EDT
Recruiting No phase listed Observational

Durability of Suppl. Rod Constructs-SuppleMentAry Rod Technique for Long-segment Posterior Instrumented Spinal Fusions

NCT06368245
View directory record Official record
Conditions
Spinal Fusion
Interventions
long-segment posterior TL instrumented fusion
Procedure
Lead sponsor
AO Foundation, AO Spine
Other
Eligibility
45 Years and older
Enrollment
1,244 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
9
States / cities
Redwood City, California • Sacramento, California • San Francisco, California + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Sep 10, 2026, 9:53 PM EDT
Active, not recruiting Not applicable Interventional

P-15L Bone Graft in Transforaminal Lumbar Interbody Fusion With Instrumentation

NCT03438747
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
P-15L Bone Graft, Local autologous bone in a TLIF with Instrumentation
Device · Other
Lead sponsor
CeraPedics, Inc
Industry
Eligibility
22 Years to 80 Years
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
34
States / cities
Birmingham, Alabama • Glendale, California • Los Angeles, California + 27 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Sep 10, 2026, 9:53 PM EDT
Not listed Not applicable Interventional

Randomized, Controlled Trial of Posterior C1-2 Fusion Versus Bracing Alone for Treatment of Type II Odontoid Process Fractures in the Elderly

NCT03788200
View directory record Official record
Conditions
Odontoid Fracture
Interventions
Bracing, posterior C1-C2 instrumented fusion
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
65 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 27, 2018 · Synced Sep 10, 2026, 9:53 PM EDT
Completed Phase 3 Interventional

Greenwich Lumbar Stenosis SLIP Study

NCT00109213
View directory record Official record
Conditions
Spinal Stenosis, Spondylolisthesis
Interventions
Lumbar Laminectomy with Instrumented Pedicle Screw Fusion, Lumbar Laminectomy
Procedure
Lead sponsor
Greenwich Hospital
Other
Eligibility
50 Years to 80 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2014
U.S. locations
5
States / cities
Greenwich, Connecticut • Boston, Massachusetts • Burlington, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Sep 10, 2026, 9:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating The Safety and Effectiveness of The NeoDisc™ Versus ACDF in Subjects With Single-Level Cervical Disc Disease

NCT00478088
View directory record Official record
Conditions
Cervical Disc Degenerative Disorder
Interventions
NeoDisc, Instrumented Anterior Cervical Discectomy and Fusion (ACDF)
Device
Lead sponsor
NuVasive
Industry
Eligibility
18 Years to 60 Years
Enrollment
488 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
22
States / cities
La Jolla, California • Marina del Rey, California • Santa Monica, California + 19 more
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 10, 2026, 9:53 PM EDT
Not yet recruiting Early Phase 1 Interventional

Evaluation of an Online Peri-operative Health Education Platform for Patients Undergoing Spine Surgery: Ready Set Recover

NCT07766824
View directory record Official record
Conditions
Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons, Chronic Low Back Pain, Scoliosis Patients, Lumbar Spondylosis, Lumbar Spondylolisthesis, Cervical Spondylosis and Spondylolisthesis, Post Laminectomy Cervical Syndrome, Cervical Myelopathy
Interventions
Ready Set Recover
Behavioral
Lead sponsor
National University of Natural Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 10, 2026, 9:53 PM EDT
Recruiting Not applicable Interventional

MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion

NCT05037968
View directory record Official record
Conditions
Degenerative Disc Disease, Spine Fusion, Leg Pain and/or Back Pain
Interventions
MagnetOs Flex Matrix, Trinity Elite
Device
Lead sponsor
Kuros Biosurgery AG
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
8
States / cities
Hartford, Connecticut • Chicago, Illinois • Columbia, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 10, 2026, 9:53 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Pivotal Study of a Facet Replacement System to Treat Spinal Stenosis

NCT00401518
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Non-randomized ACADIA® Facet Replacement System, Randomized ACADIA® Facet Replacement System, Randomized Instrumented posterolateral fusion (PLF)
Device
Lead sponsor
Globus Medical Inc
Industry
Eligibility
21 Years to 85 Years
Enrollment
390 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2017
U.S. locations
28
States / cities
Beverly Hills, California • Los Angeles, California • Rancho Mirage, California + 23 more
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced Sep 10, 2026, 9:53 PM EDT
Recruiting Not applicable Interventional

Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion

NCT04679844
View directory record Official record
Conditions
Degenerative Disc Disease, Spine Fusion, Back Pain
Interventions
MagnetOs Easypack Putty, Demineralized Bone Matrix or Fibers mixed with local autograft bone
Device
Lead sponsor
Kuros Biosurgery AG
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
6
States / cities
Irvine, California • Grand Rapids, Michigan • St Louis, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Sep 10, 2026, 9:53 PM EDT
Terminated Not applicable Interventional

Evaluation of Radiographic and Patient Outcomes Following Lumbar Spine Fusion Using Demineralized Bone Matrix (DBM) Mixed With Autograft

NCT00254852
View directory record Official record
Conditions
Stenosis, Spondylolisthesis, Degenerative Disc Disease
Interventions
Posterior Lateral Fusion (PLF), Anterior Lumbar Interbody Fusion (ALIF), Transforaminal lumbar interbody fusion (TLIF), Posterior lumbar interbody fusion (PLIF), Extreme lateral interbody fusion (XLIF)
Procedure
Lead sponsor
Exactech
Industry
Eligibility
21 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
6
States / cities
Long Beach, California • San Diego, California • New Hartford, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2013 · Synced Sep 10, 2026, 9:53 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Clinical Evaluation of GENEX® DS in Instrumented Posterolateral Fusion

NCT02317185
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Stenosis
Interventions
genex bone graft with bone graft, autogenous bone graft
Device · Other
Lead sponsor
Spine Wave
Industry
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
New York, New York • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2018 · Synced Sep 10, 2026, 9:53 PM EDT
Active, not recruiting Not applicable Interventional

SLIP II Registry: Spinal Laminectomy Versus Instrumented Pedicle Screw Fusion

NCT03570801
View directory record Official record
Conditions
Lumbar Spondylolisthesis, Grade 1 Spondylolisthesis, Lumbar Spinal Stenosis, Degenerative Spondylolisthesis
Interventions
Expert Panel Review
Other
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Enrollment
662 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
16
States / cities
Scottsdale, Arizona • San Francisco, California • Miami, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 10, 2026, 9:53 PM EDT
Terminated Not applicable Interventional

Dynamic Stabilization for Lumbar Spinal Stenosis With Stabilimax NZ® Dynamic Spine Stabilization System

NCT00529997
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Stabilimax NZ® Dynamic Spine Stabilization System
Device
Lead sponsor
Applied Spine Technologies
Industry
Eligibility
21 Years and older
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
19
States / cities
Phoenix, Arizona • Los Angeles, California • Oceanside, California + 16 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2010 · Synced Sep 10, 2026, 9:53 PM EDT
Terminated Not applicable Interventional

Effectiveness of Lumbar Fusion When NanOss Bioactive Is Used With Posterolateral Gutter Fusions

NCT01452516
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
Interventions
nanOss Bioactive Bone void filler, Interbody FCage
Device
Lead sponsor
Pioneer Surgical Technology, Inc.
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
7
States / cities
Beverly Hills, California • La Jolla, California • Chicago, Illinois + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2016 · Synced Sep 10, 2026, 9:53 PM EDT
Completed Not applicable Interventional Results available

Assessment of nanOss Bioactive 3D in the Posterolateral Spine

NCT01829997
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
Interventions
nanOss Bioactive 3D BVF
Device
Lead sponsor
Pioneer Surgical Technology, Inc.
Industry
Eligibility
21 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
4
States / cities
New York, New York • Charleston, South Carolina • Glendale, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Sep 10, 2026, 9:53 PM EDT