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ClinicalTrials.gov public records Last synced Sep 9, 2026, 11:33 PM EDT

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Showing 1–7 of 7 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Metastatic Colorectal Cancer
Interventions
Sym004 (12 mg/kg), Sym004 (9/6 mg/kg), Best Supportive Care (BSC), Fluorouracil (5-FU), Capecitabine
Drug · Other
Lead sponsor
Symphogen A/S
Industry
Eligibility
18 Years and older
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
9
States / cities
Los Angeles, California • San Diego, California • Fort Myers, Florida + 6 more
Completed Phase 1Phase 2 Interventional Results available

Sym004 in Patients With Advanced Solid Tumors

NCT01117428
Conditions
Metastatic Colorectal Cancer
Interventions
Sym004
Drug
Lead sponsor
Symphogen A/S
Industry
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Metastatic Colorectal Cancer
Interventions
Sym004, FOLFIRI
Drug
Lead sponsor
Symphogen A/S
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
5
States / cities
Los Angeles, California • San Diego, California • Washington D.C., District of Columbia + 2 more
Conditions
Metastatic Colorectal Cancer
Interventions
Futuximab/modotuximab, Trifluridine/Tipiracil
Biological · Drug
Lead sponsor
Institut de Recherches Internationales Servier
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Ann Arbor, Michigan • Cleveland, Ohio
Conditions
Metastatic Colorectal Cancer, Colorectal Cancer Metastatic, Carcinoma
Interventions
Sym004, Futuximab, Modotuximab
Drug
Lead sponsor
Symphogen A/S
Industry
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
5
States / cities
Duarte, California • Atlanta, Georgia • Boston, Massachusetts + 2 more
Conditions
Solid Tumor
Interventions
S095029, S95029 and Sym021
Drug
Lead sponsor
Institut de Recherches Internationales Servier
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
4
States / cities
Grand Rapids, Michigan • Dallas, Texas • Houston, Texas + 1 more
Conditions
Malignant Glioma
Interventions
Sym004 - 18 mg/kg, Sym004 - 24 mg/kg
Drug
Lead sponsor
Annick Desjardins
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Durham, North Carolina