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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Gain Framed Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Decision-Framing in Psoriasis

NCT04136314
View directory record Official record
Conditions
Psoriasis Vulgaris, Psoriatic Arthritis, Psoriasis
Interventions
Decision-Framed Survey
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 14, 2022 · Synced Sep 2, 2026, 6:42 AM EDT
Recruiting Not applicable Interventional

Telehealth Collaborative Care Model (CoCM) in Lung Cancer

NCT07102147
View directory record Official record
Conditions
Lung Cancer (Diagnosis), Anxiety, Depression in Adults
Interventions
High Touch Outreach
Behavioral
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional

Effect of Cigarette Pack Warnings and Packaging Among Young Adult Smokers

NCT03446170
View directory record Official record
Conditions
Tobacco Use
Interventions
Graphic cigarette warning labels, plain packaging
Behavioral
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 30 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Smartphone-paired Breathalyzers and Loss- and Gain-framed Texts for Reducing Drinking and Driving

NCT03335735
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication, Alcohol Impairment, Drive, Driving Impaired, Driving Under the Influence, Behavior, Drinking
Interventions
Loss-framed text message, Gain-Framed text message
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 39 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Sep 2, 2026, 6:42 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Implementing Tobacco Treatment in Low Dose CT Lung Cancer Screening Sites

NCT03315910
View directory record Official record
Conditions
Smoking Cessation
Interventions
Motivational Interviewing (MI), Nicotine Replacement Therapy (NRT), Nicotine Lozenge, Message Framing, saliva sample
Behavioral · Drug · Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
50 Years to 80 Years
Enrollment
807 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
18
States / cities
Los Angeles, California • Walnut Creek, California • La Grange, Georgia + 14 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Message Framing Intervention for Increasing Parental Acceptance of Human Papillomavirus Vaccination

NCT03856437
View directory record Official record
Conditions
Cervical Cancer, Anal Cancer, Penile Cancer
Interventions
HPV vaccination messages
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 99 Years
Enrollment
1,170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 14, 2024 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Understanding and Discouraging Overuse of Potentially Harmful Screening Tests

NCT01694784
View directory record Official record
Conditions
Preventive Screening, Prostate Cancer, Osteoporosis, Colorectal Cancer
Interventions
Quantitative Information Sheet, Qualitative Information Sheet, Narrative Information Sheet, Framed Information Sheet
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
50 Years to 85 Years
Enrollment
775 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2016 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional

Refinement and Testing of Recruitment Methodology for Behavioral Medication Adherence Interventions Using Behavioral Science-based Approaches

NCT06569290
View directory record Official record
Conditions
Diabetes, Pharmacist-Patient Relations, Medication Adherence
Interventions
Primer postcard, Control recruitment letter, Behavioral theory-informed recruitment letter (prospect theory), 2 phone calls, 4 phone calls
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
590 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Message Framing for Telephone Quitline Callers

NCT00589277
View directory record Official record
Conditions
Smoking, Nicotine Dependence
Interventions
Gain-Framed counseling & Gain-framed materials, Standard care counseling + standard materials
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
2,032 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Gain-framed Messages and NRT for Lung Cancer Screening Patients

NCT03069924
View directory record Official record
Conditions
Lung Cancer Screening, Smoking Cessation
Interventions
Gain-framed messaging, Unframed messaging materials
Behavioral · Combination Product
Lead sponsor
Medical University of South Carolina
Other
Eligibility
50 Years and older
Enrollment
367 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
2
States / cities
New Haven, Connecticut • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional Results available

Mobile Cognitive Behavior Therapy Targeting Anxiety Disorders

NCT05130281
View directory record Official record
Conditions
Anxiety Disorders and Symptoms
Interventions
Maya mobile app, Social Support, Gain Framed, Loss Framed
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 25 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Interventions to Increase HBV Vaccinations in Sexually Transmitted Disease (STD) Clinics

NCT00739752
View directory record Official record
Conditions
Hepatitis B Virus
Interventions
Non-Framed-Offered, Non-Framed-Recommended, Gain-Framed-Offered, Gain-Framed-Recommended, Loss-Framed-Offered, Loss-Framed-Recommended
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
1,747 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
2
States / cities
Chicago, Illinois • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 8, 2018 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Adolescent Investment In Diabetes Care

NCT04516694
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Financial incentive (gain), Financial incentive (loss)
Behavioral
Lead sponsor
Harvard Pilgrim Health Care
Other
Eligibility
12 Years to 18 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 4, 2024 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tobacco Treatment in the Context of Lung Cancer Screening

NCT03927989
View directory record Official record
Conditions
Smoking Cessation
Interventions
Text messaging plus nicotine replacement therapy, Standard Care at Lung Cancer Screening
Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
55 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 21, 2024 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional Results available

CBT Texts for PTSD & Hazardous Drinking (Project Better)

NCT05372042
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Alcohol Use
Interventions
CBT Text Messages
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
505 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Sep 2, 2026, 6:42 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Increasing CRC Screening in Community Health Centers Through Mobile Messaging Optimization

NCT07569250
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Personalized Text Message, Screening Concerns Text Message, Message Framing Text Message, Autonomy Support Outreach, Impediments Support Outreach, Live Support Outreach, Data Reporting and Visualization System Tools
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
45 Years to 75 Years
Enrollment
7,220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
4
States / cities
Boston, Massachusetts • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Framing Messages for Smoking Cessation With Bupropion - 6

NCT00104598
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Bupropion, Smoking Abstinence Program
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
252 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2006
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 8, 2013 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional

New Technology and Child Health

NCT02622035
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Provision of information, Emotion induction, visual perceptual load
Behavioral
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
18 Years to 120 Years
Enrollment
415 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Sep 2, 2026, 6:42 AM EDT
Enrolling by invitation Not applicable Interventional

Testing Alcohol Cancer Risk Messages

NCT07365813
View directory record Official record
Conditions
Alcohol, Cancer
Interventions
Text-only messages, AI-developed Neutral pictorial messages, AI-developed graphic pictorial messages
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
21 Years and older
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional Results available

Patient Portal Reminder/Recall for Influenza Vaccination in a Health System- RCT 2

NCT04110314
View directory record Official record
Conditions
Influenza, Respiratory Tract Infections
Interventions
Portal Reminders for Influenza Vaccination: Gain-framed, Portal Reminders for Influenza Vaccination: Loss-framed, Pre-commitment prompt
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
4 Months and older
Enrollment
430,636 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Cell Phone Use While Driving Among High Risk UBI Auto Policy Holders

NCT04587609
View directory record Official record
Conditions
Distracted Driving, Driving Impaired
Interventions
Free Phone Mounts, Commitment Contract, Personalized Habit Tips, Social Gamification Feedback, "Contest" Financial Incentives
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
1,668 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intern Health Study 2022 and 2023

NCT05436145
View directory record Official record
Conditions
Depression, Mood, Sleep, Physical Activity
Interventions
Intern Health Study behavioral change mobile notification
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
2,562 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing Multiple Behavioral Science Strategies to Increase Flu-Shot Rates at a Large Retail Pharmacy

NCT04590066
View directory record Official record
Conditions
Influenza, Human
Interventions
Flu shot text messages
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
734,383 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 31, 2021 · Synced Sep 2, 2026, 6:42 AM EDT
Completed Not applicable Interventional

Scaling Up: A Multi-Site Trial of e-SBI for Alcohol Use in Pregnancy

NCT04332172
View directory record Official record
Conditions
Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome, Fetal Alcohol Effect
Interventions
General information, Baseline brief intervention, Remote online booster sessions, SMS
Other · Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Sep 2, 2026, 6:42 AM EDT