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ClinicalTrials.gov public records Last synced Oct 19, 2026, 4:09 AM EDT

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Showing 1–24 of 158 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: General Anesthetics Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

Comparison of Anesthetic Techniques on Total Hip Arthroplasty

NCT01359865
View directory record Official record
Conditions
Osteoarthritis
Interventions
Lumbar Plexus Block
Procedure
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
Not listed
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 2, 2015 · Synced Oct 19, 2026, 4:09 AM EDT
Completed Phase 4 Interventional Results available

A Multi-site Randomized Controlled Trial Comparing Regional and General Anesthesia for Effects on Neurodevelopmental Outcome and Apnea in Infants

NCT00756600
View directory record Official record
Conditions
Inguinal Hernia
Interventions
Regional Anesthesia, General Anesthesia
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 60 Weeks
Enrollment
643 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
10
States / cities
Aurora, Colorado • Chicago, Illinois • Iowa City, Iowa + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2020 · Synced Oct 19, 2026, 4:09 AM EDT
Not listed Early Phase 1 Interventional

Inhalational Anesthesia vs TIVA in Endoscopic Tympanoplasty

NCT05993039
View directory record Official record
Conditions
Perforated Eardrum
Interventions
Isoflurane Inhalant Product, Sevoflurane inhalant product, Propofol injection, Remifentanil Injection
Drug
Lead sponsor
Our Lady of the Lake Hospital
Other
Eligibility
0 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Oct 19, 2026, 4:09 AM EDT
Terminated Phase 2 Interventional Results available

Impact of Total Intravenous Anesthesia Following Cancer Surgery, TIVACS Study

NCT04992507
View directory record Official record
Conditions
Pancreatic Adenocarcinoma
Interventions
Anesthesia Procedure, General Anesthesia Procedure, Resection
Procedure · Drug
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Oct 19, 2026, 4:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Task-based Credentialing for Medical Officers in Spinal Anesthesia

NCT04438811
View directory record Official record
Conditions
Spinal Anesthesia, Task Sharing in Anesthetic Delivery in Areas With Limited Access to Care
Interventions
delivery of the spinal anesthetic by a trained medical officer, delivery of spinal anesthetic by a consultant anesthetist
Other
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years to 65 Years
Enrollment
486 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Oct 19, 2026, 4:09 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Anesthetic Techniques in Outpatient Total Joint Replacement Surgery in an Integrated Health Care Delivery System

NCT04203732
View directory record Official record
Conditions
Anesthesia Morbidity, Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions
Anesthesia Type
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
12,466 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
South San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2021 · Synced Oct 19, 2026, 4:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reconstructing Consciousness and Cognition

NCT01911195
View directory record Official record
Conditions
Postoperative Cognitive Dysfunction
Interventions
ISOFLURANE- Experimental Arm, Control Group: Cognitive Testing
Drug · Other
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
3
States / cities
Ann Arbor, Michigan • St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Oct 19, 2026, 4:09 AM EDT
Completed Not applicable Interventional

Prostate Conformal Cryotherapy

NCT00877682
View directory record Official record
Conditions
Prostate Cancer
Interventions
Cryoablation
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Male only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 31, 2018 · Synced Oct 19, 2026, 4:09 AM EDT
Completed Phase 2 Interventional

Postoperative Pain Control in Children Undergoing Laparoscopic Appendectomy: Peripheral Nerve Block Versus Local Anesthetic

NCT01662401
View directory record Official record
Conditions
Postoperative Pain
Interventions
Bupivacaine
Drug
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
6 Years to 18 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 2, 2013 · Synced Oct 19, 2026, 4:09 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Anxiety Level Assessment of Anesthesia Providers During COVID-19 Pandemic

NCT05212909
View directory record Official record
Conditions
Anxiety
Interventions
General Anxiety Disorder-7 scale
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
Not listed
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 23, 2022 · Synced Oct 19, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional

Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

NCT05991453
View directory record Official record
Conditions
Surgery-Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia, Surgery, Quality of Life, Pain, Postoperative, Anesthesia Morbidity
Interventions
Anesthetic technique Propofol TIVA, Anesthetic technique inhaled agent
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
13,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
24
States / cities
Little Rock, Arkansas • San Francisco, California • Stanford, California + 18 more
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 19, 2026, 4:09 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Total Intravenous Anesthesia With Propofol vs. General Anesthesia in Outpatient Shoulder Arthroscopic Surgeries

NCT04793022
View directory record Official record
Conditions
Rotator Cuff Tears, Rotator Cuff Injuries, Orthopedic Disorder, Sports Injury, Anesthesia
Interventions
TIVA with Propofol, Inhaled Anesthesia
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 19, 2026, 4:09 AM EDT
Active, not recruiting Not applicable Interventional

Hypnosedation in Relaxing Patients Undergoing Breast Cancer Surgery

NCT03012399
View directory record Official record
Conditions
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Prognostic Stage 0 Breast Cancer AJCC v8, Prognostic Stage I Breast Cancer AJCC v8, Prognostic Stage IA Breast Cancer AJCC v8, Prognostic Stage IB Breast Cancer AJCC v8
Interventions
Hypnosedation, Questionnaire Administration, Verbal Support
Behavioral · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 19, 2026, 4:09 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects

NCT01557920
View directory record Official record
Conditions
Airway Complication of Anaesthesia, Healthy
Interventions
Propofol, Sevoflurane
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 13, 2016 · Synced Oct 19, 2026, 4:09 AM EDT
Completed Not applicable Interventional

Anesthetics in Rhytidoplasty - A Comparison Study

NCT02410460
View directory record Official record
Conditions
Rhytidoplasty
Interventions
clonidine, glycopyrrolate, propofol, ketamine, marcaine, scopolamine, midazolam, ondansetron, metoclopramide, lidocaine, famotidine, desflurane, sevoflurane
Drug · Device
Lead sponsor
Mercy Facial Plastic Surgery Center
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 19, 2026, 4:09 AM EDT
Terminated Phase 4 Interventional

Efficacy and Safety of Perampanel in the Treatment of Refractory Status Epilepticus

NCT05684978
View directory record Official record
Conditions
Refractory Status Epilepticus
Interventions
Perampanel
Drug
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 100 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 19, 2026, 4:09 AM EDT
Completed Phase 4 Interventional Results available

Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care

NCT01993836
View directory record Official record
Conditions
Alzheimers Disease, Postoperative Delirium, Post Operative Cognitive Dysfunction
Interventions
Total intravenous anesthesia with propofol, General anesthesia with isoflurane
Drug
Lead sponsor
Duke University
Other
Eligibility
60 Years and older
Enrollment
191 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 19, 2026, 4:09 AM EDT
Completed Not applicable Interventional

The Use of Serratus Block for Cardiac Surgery

NCT03237546
View directory record Official record
Conditions
Cardiac Surgery
Interventions
Anesthetic regimen including SB, Anesthetic regimen including SB or no block
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Oct 19, 2026, 4:09 AM EDT
Completed Not applicable Interventional Results available

Addition of Nitrous Oxide and Its Effects on Depth of Anesthesia

NCT00717574
View directory record Official record
Conditions
Deep Sedation, Anesthesia, General
Interventions
Sevoflurane group, Propofol group
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 31, 2017 · Synced Oct 19, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional

Effects of Erector Spinae Plane Block on Postoperative Pain Following Lumbar Fusion Surgery

NCT06528288
View directory record Official record
Conditions
Fusion of Spine, Lumbar Region, Anesthesia, Local, Pain, Postoperative, Opioid Use
Interventions
Erector Spinae Plane Block, Subcutaneous Anesthesia
Procedure
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 19, 2026, 4:09 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Peripheral Nerve Blocks in Pediatric Orthopedic Patients

NCT02236130
View directory record Official record
Conditions
Pediatric Extremity Fracture, Pediatric Extremity Soft Tissue Injury
Interventions
Regional block, General Anesthesia, Local Anesthetic Ropivacaine, Opioids Morphine, Oral pain medication Acetaminophen with Hydrocodone
Procedure · Drug
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
6 Years to 17 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Feb 13, 2017 · Synced Oct 19, 2026, 4:09 AM EDT
Recruiting No phase listed Observational

A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia

NCT05954832
View directory record Official record
Conditions
Anesthesia
Interventions
Echocardiography
Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 19, 2026, 4:09 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Two Anesthetic Techniques in Magnetic Resonance Imaging (MRI)

NCT00894751
View directory record Official record
Conditions
Magnetic Resonance Imaging, Anesthesia
Interventions
dexmedetomidine, propofol
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Months to 7 Years
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Oct 19, 2026, 4:09 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Relationship Between Anesthetic Regimen and Bone Cement Implantation Syndrome (BCIS)

NCT06952257
View directory record Official record
Conditions
Bone Cement Implantation Syndrome
Interventions
Administration of general anaesthesia, Neuraxial Analgesia
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 19, 2026, 4:09 AM EDT