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ClinicalTrials.gov public records Last synced Oct 19, 2026, 8:24 PM EDT

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Showing 97–120 of 706 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: General anesthesia Clear all
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Efficacy and Safety of HSK3486 Compared to Propofol in Induction of General Anesthesia in Adults Having Elective Surgery

NCT04711837
View directory record Official record
Conditions
Anesthesia
Interventions
HSK3486, Propofol
Drug
Lead sponsor
Haisco-USA Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
255 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
13
States / cities
Phoenix, Arizona • Pasadena, California • Tamarac, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2025 · Synced Oct 19, 2026, 8:24 PM EDT
Completed Phase 4 Interventional Results available

Effect of Neuromuscular Blockade on Pulmonary Complications in Elective Cardiac Surgery

NCT02635542
View directory record Official record
Conditions
Neuromuscular Blockade, Postoperative Complications
Interventions
Succinylcholine, Cisatracurium
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Oct 19, 2026, 8:24 PM EDT
Completed Phase 1 Interventional Results available

General Anesthesia Emergence Induced by Methylphenidate

NCT02327195
View directory record Official record
Conditions
Delayed Emergence From Anesthesia
Interventions
Methylphenidate HCl, Placebo
Drug
Lead sponsor
Nicoleta Stoicea
Other
Eligibility
18 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 12, 2022 · Synced Oct 19, 2026, 8:24 PM EDT
Terminated Not applicable Interventional Results available

SedLine Engineering Data Collection Study in Pediatric Patients Undergoing General Anesthesia or Sedation

NCT03128931
View directory record Official record
Conditions
Anesthesia
Interventions
Pediatric SedLine forehead EEG sensor
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
12 Months to 17 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2022 · Synced Oct 19, 2026, 8:24 PM EDT
Completed Not applicable Interventional Results available

Regional Versus General Anesthesia for Promoting Independence After Hip Fracture

NCT02507505
View directory record Official record
Conditions
Hip Fractures
Interventions
Regional Anesthesia, General Anesthesia
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years and older
Enrollment
1,848 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
38
States / cities
Birmingham, Alabama • Sacramento, California • Hartford, Connecticut + 31 more
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Oct 19, 2026, 8:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Reducing ESKAPE Transmission in the Operating Room

NCT06274918
View directory record Official record
Conditions
Surgical Procedure, Unspecified
Interventions
Personalized Body-Worn Alcohol Dispenser
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Oct 19, 2026, 8:24 PM EDT
Recruiting Not applicable Interventional

Early General Anesthesia to Limit Experiences of Trauma During Cesarean Section-Pilot Study

NCT07334418
View directory record Official record
Conditions
Cesarean Section, Delivery; Trauma
Interventions
General anesthetic, Intravenous anesthetic
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 19, 2026, 8:24 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Functional Outcomes of Awake vs. Asleep Deep Brain Stimulation (DBS) for Essential Tremor

NCT02418858
View directory record Official record
Conditions
Essential Tremor
Interventions
Deep Brain Stimulation surgery
Procedure
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 12, 2015 · Synced Oct 19, 2026, 8:24 PM EDT
Withdrawn Not applicable Interventional

The BALANCED Anaesthesia Study

NCT02073357
View directory record Official record
Conditions
Effect of General Anesthetic Dose on Recovery From Surgery
Interventions
Light general anaesthesia (BIS = 50), deep general anaesthesia (BIS = 35)
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
60 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 31, 2014 · Synced Oct 19, 2026, 8:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy of the Tao Facemask for Positive Pressure Ventilation in the Patients With Significantly Elevated BMIs

NCT03473366
View directory record Official record
Conditions
Anesthesia Induction Ventilation
Interventions
Tao Mask, Standard Mask
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 23, 2023 · Synced Oct 19, 2026, 8:24 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers

Rectal Acetaminophen Use During Oocyte Retrievals to Reduce Post-Operative Opioid Utilization

NCT03732469
View directory record Official record
Conditions
Opioid Use
Interventions
Acetaminophen, Fentanyl, Propofol
Drug
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 56 Years · Female only
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 18, 2021 · Synced Oct 19, 2026, 8:24 PM EDT
Withdrawn Not applicable Interventional

Desflurane Versus Isoflurane for Speeding Postanesthetic Recovery and Hospital Discharge

NCT06252207
View directory record Official record
Conditions
Surgery
Interventions
Desflurane, Isoflurane
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 19, 2026, 8:24 PM EDT
Terminated Phase 2 Interventional Results available

Perioperative Ketamine in Opioid-Tolerant Patients Undergoing Lumbar Spine Surgery

NCT04220489
View directory record Official record
Conditions
Opioid Dependence, Chronic Pain
Interventions
Ketamine, Placebo Comparator
Drug
Lead sponsor
Jacques E. Chelly
Other
Eligibility
18 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 30, 2024 · Synced Oct 19, 2026, 8:24 PM EDT
Not yet recruiting Phase 2 Interventional

Study of Psilocybin Under Anesthesia Controlled by EEG

NCT07479550
View directory record Official record
Conditions
Major Depression
Interventions
Psilocybin (Usona Institute), Propofol, Placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
25 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 19, 2026, 8:24 PM EDT
Not listed Not applicable Interventional

Laparoscopic Gastric Bypass for Type 2 Diabetes Mellitus With Body Mass Index (BMI) < 35

NCT00999050
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Gastric bypass for diabetic patients <35 BMI
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 4, 2011 · Synced Oct 19, 2026, 8:24 PM EDT
Not listed No phase listed Observational

Impact of Atelectasis on RVEDP Following Orthotropic Heart Transplantation

NCT06140810
View directory record Official record
Conditions
Heart Transplant Failure, Anesthesia
Interventions
Lung Recruitment
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Oct 19, 2026, 8:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ventilatory Strategy for the Prevention of Atelectasis During Bronchoscopy Under General Anesthesia, VESPA Trial

NCT04311723
View directory record Official record
Conditions
Lung Disorder
Interventions
Anesthesia Procedure, Bronchoscopy
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Oct 19, 2026, 8:24 PM EDT
Not listed Phase 4 Interventional

Use of Regional Anesthesia in Hip Arthroscopy

NCT02851888
View directory record Official record
Conditions
Hip Injuries
Interventions
Ropivacaine, Normal Saline Sham Injection, General Anesthesia
Drug · Other · Procedure
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 50 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 19, 2018 · Synced Oct 19, 2026, 8:24 PM EDT
Completed Phase 4 Interventional Results available

Effect of Intraoperative Anesthetic Management on Postoperative Nausea and Vomiting in Bariatric Surgery

NCT01449708
View directory record Official record
Conditions
Postoperative Nausea and Vomiting
Interventions
TIVA NoNarc
Drug
Lead sponsor
Coastal Anesthesiology Consultants
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Saint Augustine, Florida
Source: ClinicalTrials.gov public record
Updated Mar 21, 2016 · Synced Oct 19, 2026, 8:24 PM EDT
Completed Phase 3 Interventional

Study of MR-107A-02 for the Treatment of Acute Postoperative Pain Following Herniorrhaphy

NCT06215859
View directory record Official record
Conditions
Acute Pain, Post Operative Pain, Pain
Interventions
MR-107A-02, Tramadol, Placebo, Herniorrhaphy
Drug · Procedure
Lead sponsor
Viatris Specialty LLC
Industry
Eligibility
18 Years and older
Enrollment
579 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
18
States / cities
Sheffield, Alabama • Phoenix, Arizona • Anaheim, California + 13 more
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 19, 2026, 8:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pre-op Use of Incentive Spirometry in Obese Patients

NCT01004146
View directory record Official record
Conditions
Lung Function, Bariatric Surgery
Interventions
Incentive Spirometry
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 3, 2014 · Synced Oct 19, 2026, 8:24 PM EDT
Completed No phase listed Observational

The PAWS-COVID-19 (Pediatric AirWay complicationS COVID-19) Registry

NCT04449042
View directory record Official record
Conditions
Airway Management, COVID19
Interventions
airway management during sedation or general anesthesia
Procedure
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 18 Years
Enrollment
14,835 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2021 · Synced Oct 19, 2026, 8:24 PM EDT
Terminated Early Phase 1 Interventional

Liposomal Bupivacaine (Exparel) in Sarcomas

NCT03867188
View directory record Official record
Conditions
Soft Tissue Sarcoma, Soft Tissue Tumor, Soft Tissue Tumor and/or Sarcoma
Interventions
Liposomal Bupivacaine
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Oct 19, 2026, 8:24 PM EDT
Completed Not applicable Interventional Results available

Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy

NCT02205801
View directory record Official record
Conditions
Thyroid Neoplasms, Goiter, Nodular, Thyroid Nodule, Graves' Disease, Hyperparathyroidism
Interventions
Superficial Cervical Plexus Block, Local Wound Infiltration, 0.9% saline, Marcaine
Procedure · Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 9, 2018 · Synced Oct 19, 2026, 8:24 PM EDT