- Conditions
- Endodontic Disease, Periapical Diseases, Periapical Periodontitis, Root Canal Infection
- Interventions
- Irrisafe ip, GentleWave System, Waterlase iPlus
- Device
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 14 Years to 99 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2025
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–10
of 10
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Root Canal Treatment
- Interventions
- GentleWave
- Device
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Root Canal
- Interventions
- Sonendo GentleWave™ System
- Device
- Lead sponsor
- Sonendo, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 1
- States / cities
- Laguna Hills, California
- Conditions
- Apical Periodontitis
- Interventions
- GentleWave System, Conventional rotary instrumentation with passive ultrasonic irrigation
- Procedure
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027 – 2030
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Dental Pulp Necroses
- Interventions
- GentleWave System Root Canal Therapy, EdgePro Laser Root Canal Therapy, The ProUltra Piezo Ultrasonic with EndoUltra Tips Root Canal Therapy
- Device
- Lead sponsor
- Abhishek Parolia
- Other
- Eligibility
- 18 Years to 95 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Pain, Postoperative, Root Canal Infection, Endodontically Treated Teeth
- Interventions
- GentleWave, Conventional Protocol
- Other
- Lead sponsor
- University of Salamanca
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 70 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Manhattan, New York
- Conditions
- Apical Periodontitis
- Interventions
- GentleWave System
- Device
- Lead sponsor
- University of Iowa
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Root Canal Therapy
- Interventions
- Sonendo GentleWave™ System
- Device
- Lead sponsor
- Sonendo, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 3
- States / cities
- Aliso Viejo, California • Santa Ana, California • Whittier, California
- Conditions
- Root Canal Infection, Endodontic Disease, Endodontic Inflammation, Post-Operative Pain
- Interventions
- Gentlewave, Standard Endodontic Protocol
- Device · Procedure
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 87 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Root Canal
- Interventions
- GentleWave System Treatment
- Device
- Lead sponsor
- Sonendo, Inc.
- Industry
- Eligibility
- Not listed
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2018
- U.S. locations
- 3
- States / cities
- Encinitas, California • Santa Ana, California • Whittier, California