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Showing 1–24 of 85 matching trials from the live ClinicalTrials.gov search.

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Filters: Intervention: Ghrelin Clear all

Conditions: Obesity
Interventions: Oral Glucose Tolerance Test (OGTT), Human Ghrelin, Saline; Procedure · Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 21 Years to 65 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2023
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Gastroesophageal Disease
Interventions: Not listed
Lead sponsor: Southern Arizona VA Health Care System; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Maternal Obesity Syndrome
Interventions: cross-sectional; Other
Lead sponsor: University of Wyoming; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2014
U.S. locations: 1
States / cities: Laramie, Wyoming

Conditions: Type 2 Diabetes Mellitus
Interventions: Synthetic human AG, Arginine, 0.9% saline solution; Drug
Lead sponsor: Jenny Tong, MD, MPH; Other
Eligibility: 18 Years to 70 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Constipation
Interventions: RM-131, Placebo; Drug
Lead sponsor: Motus Therapeutics, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 3
States / cities: Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota

Conditions: Appetite and General Nutritional Disorders
Interventions: HP-Beverage Breakfast, HP-Solid Breakfast, Breakfast Skipping; Behavioral
Lead sponsor: Purdue University; Other
Eligibility: 20 Years to 32 Years
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Diabetes, Gastric Bypass
Interventions: Mixed Meal Tolerance test, Hyperglycemic clamp; Procedure
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 19 Years to 65 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Healthy Volunteers, Obesity
Interventions: Ghrelin, Saline; Drug
Lead sponsor: Jenny Tong, MD, MPH; Other
Eligibility: 18 Years to 40 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Chronic Kidney Disease, End Stage Renal Disease
Interventions: MK-0677, Placebo; Drug
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 99 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Obesity, Weight Loss, Body Weight, Hepatocellular Carcinoma, HCC, Hepatitis C, Cirrhosis
Interventions: Embospheres Microspheres; Device
Lead sponsor: St. Louis University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2027
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Frailty Syndrome
Interventions: Ghrelin, Placebo; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 70 Years and older
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Cancer Cachexia
Interventions: Anamorelin HCl, Placebo; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Aging, Frail Older Adults
Interventions: CP-424,391; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 65 Years to 84 Years
Enrollment: 396 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2001
U.S. locations: 12
States / cities: Palo Alto, California • San Diego, California • Hamden, Connecticut + 9 more

Conditions: Alcoholism
Interventions: Ghrelin, Saline solution; Drug
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2011
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Aging
Interventions: Orally active growth hormone secretagogue (MK-677); Drug
Lead sponsor: University of Virginia; Other
Eligibility: 60 Years and older
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1998 – 2004
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Obesity
Interventions: human ghrelin, very low calorie diet, Hyperinsulinemic/Euglycemic Clamp; Drug · Other · Procedure
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Fibromyalgia
Interventions: Ibutamoren Mesylate (MK-0677); Drug
Lead sponsor: Bennett, Robert, M.D.; Individual
Eligibility: 30 Years to 65 Years · Female only
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Metastatic Pancreatic Cancer
Interventions: Anamorelin Hydrochloride, Placebo; Drug
Lead sponsor: Lahey Clinic; Other
Eligibility: 18 Years and older
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Burlington, Massachusetts

Conditions: Obesity, Weight Loss, Body Weight, Nonalcoholic Steatohepatitis, Nonalcoholic Fatty Liver Disease, NAFLD
Interventions: Embospheres Microspheres; Device
Lead sponsor: Keith Pereira, MD:; Other
Eligibility: 22 Years to 65 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Obesity, Diabetes
Interventions: Not listed
Lead sponsor: Loyola University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 2,506 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2024
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Peripheral Artery Disease
Interventions: Ghrelin, Placebo; Drug
Lead sponsor: Northwestern University; Other
Eligibility: 55 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Overweight, Obesity
Interventions: Breakfast Skipping, Normal Protein Breakfast Meals, Protein-rich Breakfast Meals; Behavioral
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 15 Years to 20 Years · Female only
Enrollment: 22 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Sarcopenia, Osteopenia
Interventions: Anamorelin Hydrochloride, Placebo; Drug
Lead sponsor: Tufts University; Other
Eligibility: 50 Years and older
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Growth Hormone Deficiency (GHD)
Interventions: LUM-201, Matched Placebo (Capsules); Drug · Other
Lead sponsor: Lumos Pharma; Industry
Eligibility: 3 Years to 11 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 29
States / cities: Birmingham, Alabama • Madera, California • Orange, California + 26 more