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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:13 AM EST

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Showing 1–24 of 26 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Glucose + Fructose beverage Clear all

Conditions: Body Weight Changes
Interventions: 40% Fat Diet, 20% Fructose Beverage, 20% Glucose Beverage; Other
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 28 Years to 55 Years
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Fasting, Non-alcoholic Fatty Liver Disease (NAFLD)
Interventions: Fasting, Diet, oral carbohydrate challenge; Behavioral · Dietary Supplement
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Low-grade Chronic Inflammation, Intestinal Permeability, Type 2 Diabetes Mellitus, Cardiovascular Disease, Obesity
Interventions: Fructose-sweetened beverages, Glucose-sweetened beverages, High-fructose corn syrup-sweetened beverages; Other
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Intestinal Health
Interventions: "Humanized" galacto-oligosaccharides (hGOS), Galacto-oligosaccharides (GOS), Matching Placebo; Dietary Supplement · Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 55 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Non-alcoholic Fatty-liver Disease
Interventions: Fructose Drink, Glucose Drink; Dietary Supplement
Lead sponsor: Emory University; Other
Eligibility: 11 Years to 18 Years
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Pre-diabetes
Interventions: Honey, High Fructose Corn Syrup 55 (HFCS 55), CHO (sugar); Dietary Supplement
Lead sponsor: USDA Grand Forks Human Nutrition Research Center; Federal
Eligibility: 20 Years to 80 Years
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Grand Forks, North Dakota

Conditions: Weight Loss, Other Effects of High Altitude
Interventions: Standard pro, High pro, carbo bev, placebo bev; Other
Lead sponsor: United States Army Research Institute of Environmental Medicine; Federal
Eligibility: 18 Years to 42 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Natick, Massachusetts

Conditions: Food Preferences, Appetitive Behavior
Interventions: Sucrose drink, Glucose drink, Fructose drink; Other
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: NAFLD
Interventions: Sugar drink; Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 12 Years to 40 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Kannapolis, North Carolina

Conditions: Metabolic Syndrome, Insulin Resistance, Dyslipidemia
Interventions: Glucose, Fructose; Other
Lead sponsor: University of California, Davis; Other
Eligibility: 40 Years to 72 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2012
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Insulin Sensitivity, Insulin Tolerance
Interventions: high fructose sweetened beverage, High Glucose sweetened beverage; Dietary Supplement
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 15 Years to 20 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Conditions: None. Focus: Understanding the Obesogenic Potential of Fructose Containing Sugars
Interventions: Beverage Consumption; Other
Lead sponsor: Rippe Lifestyle Institute; Industry
Eligibility: 20 Years to 60 Years
Enrollment: 225 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2013
U.S. locations: 1
States / cities: Celebration, Florida

Conditions: Menstrual Irregularity
Interventions: Artificially Sweetened Carbohydrate Beverage, Artificially Sweetened Beverage; Dietary Supplement
Lead sponsor: University of Colorado, Colorado Springs; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 64 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Colorado Springs, Colorado

Conditions: Overweight, Obesity
Interventions: Fructose, glucose, non-caloric sweetener; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 25 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Metabolic Syndrome, Insulin Resistance, Dyslipidemia
Interventions: Glucose, Fructose, High-Fructose Corn Syrup, No sugar (Aspartame); Other
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years to 40 Years
Enrollment: 214 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Healthy
Interventions: Fructose Ingestion, Glucose Ingestion; Dietary Supplement
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 64 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Inflammation
Interventions: Water, Mini banana, Cavendish banana, 6% sugar beverage; Other
Lead sponsor: Appalachian State University; Other
Eligibility: 18 Years to 55 Years · Male only
Enrollment: 23 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Kannapolis, North Carolina

Conditions: Diabetes Mellitus, Type 2, Cystic Fibrosis
Interventions: Oral Glucose Tolerance Test, High Glycemic Index Meal, Low Glycemic Index Meal, Test Soda, Fruit juice; Other
Lead sponsor: Emory University; Other
Eligibility: 1 Year and older
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Elevated Triglycerides, Diabetes, Cardiovascular Disease, Dyslipidemia
Interventions: Fructose + Glucose Beverage; Other
Lead sponsor: The Rogosin Institute; Other
Eligibility: 18 Years to 35 Years
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 2
States / cities: New York, New York

Conditions: Type 1 Diabetes, De Novo Lipogenesis
Interventions: Oral Glucose Tolerance Test; Diagnostic Test
Lead sponsor: Yale University; Other
Eligibility: 13 Years to 22 Years
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Healthy
Interventions: Dr Pepper sweetened with sucrose or high fructose corn syrup; Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Adolescent Obesity
Interventions: Fructose + Glucose Beverage; Other
Lead sponsor: The Rogosin Institute; Other
Eligibility: 12 Years to 21 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Olipop, Poppi, Coca Cola - Classic, Diet Coke
Interventions: Prebiotic Soda 1, Prebiotic Soda 2, Diet Soda, Regular Coke; Other
Lead sponsor: Texas Christian University; Other
Eligibility: 18 Years to 40 Years · Male only
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Postprandial Glucose, GLP-1 Concentration, Satiety
Interventions: Sucrose Beverage, Glucose + Fructose beverage, Sucrose with EGCG Beverage, Glucose-Fructose with EGCG Beverage; Dietary Supplement
Lead sponsor: Purdue University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: West Lafayette, Indiana

Search by objective public record fields.

Effect of Dietary Fat When Eaten With Fructose Versus Glucose

Regulation of FGF21 by Nutritional Challenges

Diet and Systemic Inflammation

Safety, Tolerability, and Biosignature of Humanized Prebiotics in Healthy Adults

Effects of Dietary Fructose Reduction in Children With Hepatic Steatosis

Glycemic Effects of Honey

Substrate Utilization, Exercise Performance, and Skeletal Muscle Response to Energy Deficit and Altitude Acclimatization

The Impact of the Physiological Response to Sugar on Brain Activity and Behavior

Genetic-specific Effects of Fructose on Liver Lipogenesis

Effects of Consuming Sugar-Sweetened Beverages With Meals for 10 Weeks

Effects of Sugar Sweetened Beverage on Metabolic Health in Male and Female Adolescents

A Comparison of the Neurocognitive and Metabolic Effects of Fructose, Glucose, High Fructose Corn Syrup and Sucrose at Normal Population Consumed Levels in Adults Ages 20-60 Years Old

Timing of Energy Availability on Menstrual Cycle Function

Sweetened Beverages and Food Intake

The Metabolic Effects of Consuming Sugar-Sweetened Beverages for Two Weeks

Metabolic Effects of Fructose Intake

Banana Cultivars and Exercise Performance and Recovery

Redox Imbalance and the Development of Cystic Fibrosis Diabetes

Change of Fructose to Fat in South Asians

Pathogenesis of the Cardiometabolic Risk in Youth With Type 1 Diabetes

Pharmacokinetics and Pharmacodynamics of Fructose

Fructose-induced Hepatic De Novo Lipogenesis in Adolescents With Obesity

Impact of Prebiotic Sodas on Satiety and Metabolic Responses in Healthy Men

Postprandial Glycemic and GLP-1 Responses to Modified Full-sugar Drinks