- Conditions
- Cognitive Impairment, Estrogen Deficiency, Menopause, Endothelial Dysfunction, Vascular Stiffness
- Interventions
- GnRHant + E2, GnRHant + Placebo
- Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 50 Years · Female only
- Enrollment
- 19 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 2
- States / cities
- Aurora, Colorado • Boulder, Colorado
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- Conditions
- Heart Diseases, Left Ventricular Dysfunction
- Interventions
- Estradiol patch, Cetrotide, Fasting, Lower Body Negative Pressure
- Drug · Other
- Lead sponsor
- The University of Texas at Arlington
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2024
- U.S. locations
- 1
- States / cities
- Arlington, Texas
- Conditions
- Arterial Stiffening, Aging, Menopause
- Interventions
- GnRHant - Ganirelix acetate, Transdermal estradiol patch, Transdermal placebo patch
- Drug
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 18 Years to 70 Years · Female only
- Enrollment
- 155 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2007 – 2012
- U.S. locations
- 1
- States / cities
- Aurora, Colorado