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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Goal-directed Therapy group Clear all
Completed Not applicable Interventional

Safety and Feasibility of Paired Vagus Nerve Stimulation With Rehabilitation for Improving Upper Extremity Function in People With Cervical Spinal Cord Injury

NCT05601661
View directory record Official record
Conditions
Cervical Spinal Cord Injury
Interventions
Active VNS, Sham VNS, Arm rehabilitation
Device · Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Sep 26, 2026, 11:02 AM EDT
Completed Not applicable Interventional

Physical Activity Intervention for Older Patients During Chemotherapy for Colorectal Cancer

NCT02191969
View directory record Official record
Conditions
Colorectal Cancer, Fatigue
Interventions
Walk With Ease
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
60 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 30, 2020 · Synced Sep 26, 2026, 11:02 AM EDT
Completed Not applicable Interventional Results available

Multi-Component Prehabilitation for Major Elective Surgery

NCT05752474
View directory record Official record
Conditions
Frailty, Functional Recovery, Prehabilitation
Interventions
Exercise, Nutrition, Meditation, Cognitive Behavioral Intervention
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Sep 26, 2026, 11:02 AM EDT
Completed Not applicable Interventional

Impact of Non-traditional Guitar Group Instruction on Functional Movement and Well-being in Parkinson's Disease Patients

NCT02925065
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Non-traditional group guitar instruction
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 89 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 1, 2018 · Synced Sep 26, 2026, 11:02 AM EDT
Completed Not applicable Interventional

Goal Directed Fluid Management Based on Non-invasive Monitoring

NCT01883752
View directory record Official record
Conditions
Postoperative Complication
Interventions
Goal-directed Therapy group
Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
334 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2016 · Synced Sep 26, 2026, 11:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wraparound for High-risk Families with Substance Use Disorders: Examining Family, Child, and Parent Outcomes

NCT04637581
View directory record Official record
Conditions
Substance-Related Disorders, Depression, Stress Disorders, Post-Traumatic, Child Abuse, Child Neglect
Interventions
Wraparound
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
4
States / cities
Claremont, New Hampshire • Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 26, 2026, 11:02 AM EDT
Withdrawn Not applicable Interventional

Impact of GDT in Robot-assisted Laparoscopic Urological Surgery for Low to Moderate Risk Patients

NCT03213574
View directory record Official record
Conditions
Vascular Hypotension, Hypovolemia, Hypervolemia
Interventions
Control Group, Treatment Group
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Sep 26, 2026, 11:02 AM EDT
Recruiting Not applicable Interventional

Effectiveness of Motivation Skills Training (MST)

NCT05805397
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder
Interventions
Motivation Skills Training, Healthy Behaviors Control Group
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 26, 2026, 11:02 AM EDT
Active, not recruiting Not applicable Interventional

Pursuing Exploration Into the Supportive Care Needs and Intervention Preferences of Survivors of Testicular Cancer

NCT07228637
View directory record Official record
Conditions
Testicular Cancer
Interventions
Acceptance and Commitment Therapy (ACT) Coaching, Education and Support Coaching
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Sep 26, 2026, 11:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Agitation in People With Dementia: the Customized Activity Trial

NCT01892579
View directory record Official record
Conditions
Dementia
Interventions
Tailored Activity Program, Home Safety and Education Program
Behavioral · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 22, 2019 · Synced Sep 26, 2026, 11:02 AM EDT
Completed Not applicable Interventional Results available

A Prospective Study Evaluating the Use of Intraoperative Stroke Volume Variation Via the FloTrac Device to Guide Fluid and Vasopressor Management in Head and Neck Free Flaps

NCT02186938
View directory record Official record
Conditions
Head and Neck Cancer, Patients Requiring a Free Flap Surgery
Interventions
FloTrac
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 19, 2018 · Synced Sep 26, 2026, 11:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Healthy Living Partnership to Prevent Diabetes

NCT00631345
View directory record Official record
Conditions
Prediabetes, Obesity
Interventions
Group-Based Lifestyle Intervention (Phases 1 and 2), Individual Education Program (All Phases), Self-Directed Maintenance (Phase 3), Extended Group Maintenance (Phase 3)
Behavioral · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older
Enrollment
301 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Sep 26, 2026, 11:02 AM EDT
Recruiting Not applicable Interventional

Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma

NCT07704918
View directory record Official record
Conditions
Melanoma
Interventions
Statins (atorvastatin, rosuvastatin, simvastatin, or pravastatin), +/- ezetimibe, +/- PCSK9 inhibitor (alirocumab, evolocumab, inclisiran)
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
55 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 26, 2026, 11:02 AM EDT
Completed Phase 4 Interventional Results available

The Back Pain Consortium Research Program Study

NCT04870957
View directory record Official record
Conditions
Chronic Low-back Pain
Interventions
PainGuide, MBSR, PT and exercise, Self -administered acupressure, Duloxetine, Pro-Diary monitor
Behavioral · Device · Drug
Lead sponsor
University of Michigan
Other
Eligibility
25 Years to 70 Years
Enrollment
494 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 26, 2026, 11:02 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Thirty Million Words Home Visiting

NCT02216032
View directory record Official record
Conditions
Language Environments of Children of Low-socioeconomic Status
Interventions
TMW Curriculum, Nutrition Curriculum
Other
Lead sponsor
University of Chicago
Other
Eligibility
13 Months to 16 Months
Enrollment
206 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Sep 26, 2026, 11:02 AM EDT
Recruiting No phase listed Observational

Active Surveillance in Older Women With ER+ Breast Cancer

NCT07262138
View directory record Official record
Conditions
Early Stage Estrogen Receptor (ER) Positive Breast Cancer
Interventions
Active Surveillance
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
70 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 26, 2026, 11:02 AM EDT
Recruiting Not applicable Interventional

Wheelchair User Physical Activity Training Intervention to Enhance Cardiometabolic Health

NCT06013046
View directory record Official record
Conditions
Physical Disability
Interventions
Intensity-controlled physical activity training (IPAT), Education and Access (EA)
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 26, 2026, 11:02 AM EDT
Recruiting Not applicable Interventional

Telephone Support in Advanced Gastrointestinal Cancer

NCT06532877
View directory record Official record
Conditions
Gastrointestinal Neoplasm Malignant, Caregiver Burden
Interventions
Acceptance and Commitment Therapy, Education/Support
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
488 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
4
States / cities
Chicago, Illinois • Indianapolis, Indiana • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 26, 2026, 11:02 AM EDT
Terminated Not applicable Interventional Results available

Does Perioperative Goal Directed Therapy Using Flotrac Improve Outcomes in Esophagectomy Patients

NCT02864355
View directory record Official record
Conditions
Esophageal Cancer
Interventions
Goal Directed Therapy
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Sep 26, 2026, 11:02 AM EDT
Recruiting Not applicable Interventional

Training Response Artificial Intelligence Network (TRAIN)

NCT05903573
View directory record Official record
Conditions
Amnestic Mild Cognitive Impairment
Interventions
Cognitive Training, Computerized Cognitive Stimulation
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 100 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Sep 26, 2026, 11:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Technology to Support Physical Therapy Exercise

NCT03428893
View directory record Official record
Conditions
Osteoarthritis of Knee, Osteoarthritis Of Hip
Interventions
Mobile Application
Device
Lead sponsor
University of Vermont
Other
Eligibility
50 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
South Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 27, 2021 · Synced Sep 26, 2026, 11:02 AM EDT
Completed Phase 2 Interventional Results available

Hemodynamics and Extravascular Lung Water in Acute Lung Injury

NCT00624650
View directory record Official record
Conditions
Acute Lung Injury
Interventions
Diuresis (furosemide) part I, Fluid Bolus (crystalloid or albumin), Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine), Dobutamine, Concentrate all drips and nutrition, Diuresis (furosemide) part II, Dialysis
Drug · Other · Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
3
States / cities
Clackamas, Oregon • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Sep 26, 2026, 11:02 AM EDT
Enrolling by invitation Not applicable Interventional

Sampling Therapeutic Effects and Progress in Cerebral Palsy (STEP-CP)

NCT07752030
View directory record Official record
Conditions
Cerebral Palsy (CP)
Interventions
Physical Therapy Gait Training
Behavioral
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
16 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 26, 2026, 11:02 AM EDT
Completed Not applicable Interventional

Impact of Self-directed Goals for Long-term Patients in a Forensic Hospital: A Mixed-Methods Pilot Study

NCT07035210
View directory record Official record
Conditions
Occupational Deprivation, Forensic Mental Health
Interventions
Group and 1:1 occupational therapy sessions
Behavioral
Lead sponsor
Chapin Graham
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Cranston, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Sep 26, 2026, 11:02 AM EDT