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ClinicalTrials.gov public records Last synced Oct 18, 2026, 6:20 AM EDT

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Showing 1–24 of 52 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Graded Exercise Test Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Ergogenic Effects of Sportlegs

NCT06371521
View directory record Official record
Conditions
Performance Enhancing Product Use
Interventions
Sportlegs, Placebo
Dietary Supplement
Lead sponsor
Christopher Bell
Other
Eligibility
18 Years to 30 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 12, 2024 · Synced Oct 18, 2026, 6:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Graded Exercise Hypoxia Testing

NCT06901284
View directory record Official record
Conditions
Hypoxia
Interventions
Graded Exercise Test, Graded Hypoxia Exercise Test
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
2
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 18, 2026, 6:20 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Effect Of Single-Dose PF-05175157 On Metabolic And Cardiopulmonary Parameters

NCT01819922
View directory record Official record
Conditions
Healthy
Interventions
PF-05175157, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2016 · Synced Oct 18, 2026, 6:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Relationship Between Irisin and Bone Health in Individuals With Spinal Cord Injury

NCT05319522
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Acute Exercise
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 18, 2026, 6:20 AM EDT
Completed Not applicable Interventional

Improving Age-Related Cognitive Decline With Exercise in Hypertensive Older Adults

NCT05043454
View directory record Official record
Conditions
Hypertension
Interventions
High Intensity Interval Training (HIIT) Exercise
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 18, 2026, 6:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Corticospinal Activation for Improved Walking Function

NCT03237234
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Motor Skill Training, Transcranial direct current stimulation (tDCS)
Other · Device
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 12, 2022 · Synced Oct 18, 2026, 6:20 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

High-Intensity Interval Training and Regulatory T Cells

NCT04774484
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
High Intensity Interval Training
Other
Lead sponsor
Francesc Marti
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Oct 18, 2026, 6:20 AM EDT
Completed Not applicable Interventional

Effect of Hypoglycemia on Sleep

NCT02687893
View directory record Official record
Conditions
Hypoglycemia
Interventions
Aerobic Exercise, Resistance Exercise
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years to 45 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 10, 2019 · Synced Oct 18, 2026, 6:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Work-Related Effects of Heat, Activity, and Fat in Middle Aged Men

NCT02532725
View directory record Official record
Conditions
Obesity, Gender, Problem of Aging
Interventions
Cardiopulmonary Exercise Stress Test, Climatic-Controlled Cardiopulmonary Exercise Stress Test, Body Composition Evaluation, Pre-Exercise Risk Assessment
Procedure
Lead sponsor
Freeman-Sheldon Research Group, Inc.
Other
Eligibility
35 Years to 55 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1972
U.S. locations
1
States / cities
Buckhannon, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 26, 2015 · Synced Oct 18, 2026, 6:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Chronotropic Incompetence in Patients With HFpEF

NCT02524145
View directory record Official record
Conditions
Heart Failure
Interventions
Static Handgrip, Dexmedetomidine, Glycopyrrolate, Isoproterenol
Other · Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 6, 2020 · Synced Oct 18, 2026, 6:20 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

: Vascular Function in Health and Disease

NCT02966665
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Pulmonary Artery Hypertension, Heart Failure, Hypertension
Interventions
Maximum Exercise Tests, BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate, BQ-123, Fexofenadine, Ranitidine, Angiotensin-II, Valsartan, Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine, BQ-123, MitoQ, BH4
Other · Drug
Lead sponsor
D. Walter Wray
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2030
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 18, 2026, 6:20 AM EDT
Completed Not applicable Interventional

Feasibility of Aerobic Exercise for Recovery From Work-related Concussion

NCT06263179
View directory record Official record
Conditions
Concussion, Brain
Interventions
Target Heartrate Aerobic Exercise
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 40 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Williamsville, New York
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 18, 2026, 6:20 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Impact of Aerobic Exercise on Pain Modulation in Healthy Adults

NCT07083219
View directory record Official record
Conditions
Healthy Adult
Interventions
Aerobic High Intensity Interval Training
Behavioral
Lead sponsor
University of Texas, El Paso
Other
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 18, 2026, 6:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The First 20 Fire Academy Recruits Exercise Training Program

NCT03319394
View directory record Official record
Conditions
Physical Fitness
Interventions
The First Twenty, Comparison
Behavioral
Lead sponsor
Kansas State University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Manhattan, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 24, 2017 · Synced Oct 18, 2026, 6:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pro-rEsolving and pRo-inflammatory reSPonses to Acute exhaustIve exeRcisE in Healthy Individuals

NCT05923125
View directory record Official record
Conditions
Exercise
Interventions
Graded-Intensity Treadmill Exercise Protocol
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Oct 18, 2026, 6:20 AM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers

The Study of Skeletal Muscle Blood Flow in Becker Muscular Dystrophy

NCT02653833
View directory record Official record
Conditions
Muscular Dystrophy
Interventions
Tadalafil 20 MG, beetroot juice extract
Drug · Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 45 Years · Male only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2020 · Synced Oct 18, 2026, 6:20 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Submaximal Cardiopulmonary Exercise Testing for Detection of Myocardial Injury After Noncardiac Surgery

NCT06474754
View directory record Official record
Conditions
Myocardial Injury After Non-cardiac Surgery, Submaximal Exercise Performance, Preoperative Period
Interventions
High-sensitivity troponin, serum, Submaximal Cardiopulmonary Exercise Testing, Duke Activity Status Index
Diagnostic Test
Lead sponsor
Yale University
Other
Eligibility
45 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 18, 2026, 6:20 AM EDT
Completed Not applicable Interventional

Impact of Non-glucose Signals on Glycemic Control in Patients With Type 1 Diabetes

NCT03307850
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Observation During Exercise and Stress
Other
Lead sponsor
Sansum Diabetes Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Santa Barbara, California • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 5, 2018 · Synced Oct 18, 2026, 6:20 AM EDT
Completed Not applicable Interventional Results available

Exercise Training Effects on Cognition and Brain Function in Multiple Sclerosis: Project EXACT

NCT03677440
View directory record Official record
Conditions
Multiple Sclerosis, Cognitive Impairment
Interventions
Treadmill Walking Exercise Training, Stretching-and-Toning Exercise Training
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 18, 2026, 6:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Total Sleep Deprivation on Vascular Function

NCT04535219
View directory record Official record
Conditions
Sleep Deprivation
Interventions
Exercise, Supervised Total Sleep Deprivation
Other
Lead sponsor
University of Florida
Other
Eligibility
20 Years to 60 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 29, 2023 · Synced Oct 18, 2026, 6:20 AM EDT
Recruiting Not applicable Interventional

Breast Cancer, Reasoning, and Activity Intervention

NCT04816006
View directory record Official record
Conditions
Breast Cancer, Breast Neoplasms, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Cancer-related Cognitive Dysfunction
Interventions
Aerobic Exercise Training, Health Education (Active comparator)
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
50 Years and older · Female only
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 18, 2026, 6:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Work Rate Adjustments During a High-intensity Interval Training on a Stationary Bike in a Hot and Temperate Environment

NCT05988606
View directory record Official record
Conditions
High-Intensity Interval Training, Heat
Interventions
15 minutes of high-intensity interval training, 43 minutes of high-intensity interval training, Hot environment, Temperate environment
Behavioral · Other
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
18 Years to 39 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 18, 2026, 6:20 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Evaluating Q-Collar Effects on Brain Blood Flow Control During Exercise

NCT06826781
View directory record Official record
Conditions
Healthy
Interventions
Q30 Q-Collar, Not wearing Q-Collar
Device · Other
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 30 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 18, 2026, 6:20 AM EDT
Active, not recruiting Not applicable Interventional

Improving Cardiac Rehabilitation Exercise Using Target Heart Rate Trial

NCT05925634
View directory record Official record
Conditions
Myocardial Infarction, Coronary Artery Bypass, Percutaneous Coronary Intervention, Heart Failure, Cardiac Valve Surgery
Interventions
RPE (usual care), GXT+THHR (intervention)
Behavioral
Lead sponsor
Baystate Medical Center
Other
Eligibility
60 Years to 99 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Springfield, Massachusetts • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Oct 18, 2026, 6:20 AM EDT